Future Directions in Biocatalysis

Future Directions in Biocatalysis

2nd Edition - August 11, 2017

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  • Editor: Tomoko Matsuda
  • Hardcover ISBN: 9780444637437
  • eBook ISBN: 9780444637505

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Future Directions in Biocatalysis, Second Edition, presents the future direction and latest research on how to utilize enzymes, i.e., natural catalysts, to make medicines and other necessities for humans. It emphasizes the most important and unique research on biocatalysis instead of simply detailing the ABC’s on the topic. This book is an indispensable tool for new researchers in the field to help identify specific needs, start new projects that address current environmental concerns, and develop techniques based on green technology. It provides invaluable hints and clues for conducting new research on enzymes, with final sections outlining future directions in biocatalysis further expanding the science into new applications.

Key Features

  • Gives future directions in the area of biocatalysis research
  • Presents research topics based on their uniqueness, originality, and novelty
  • Includes many explanatory figures to demonstrate concepts to both organic chemists and biochemists
  • Shows that there is no boundary between organic chemistry and biochemistry


University and industry researchers with their specialties in synthetic organic chemistry, biocatalysis, or enzymology: chemists and chemical engineers, biochemists, researchers in chemical and pharmaceutical industries, plus as a reference book for graduate courses in bioorganic engineering and bioengineering

Table of Contents

  • Green chemistry related topics

    1. Biotransformation Using Liquid or Supercritical CO2

      Tomoko Matsuda and Hai Nam Hoang

    2. Biotransformation in Ionic Liquid

      Toshiyuki Itoh

    3. Photobiocatalysis

      Rio Yamanaka and Kaoru Nakamura

    Interesting enzymes and reactions

    4. Alcohol Dehydrogenase, Olefin Reduction, Non-Heme Iron Enzymes

      Jon Stewart

    5. Imine Reductase

      Koichi Mitsukura

    6. Developments in Flavoenzyme Discovery

      Marco Fraaije

    7. Carboxylation

      Kohtaro Kirimura

    8. Luciferase as biocatalysts

      Dai-ichiro Kato

    9. Enzymes in Aldoxime-Nitrile Pathway: Versatile Tools in Biocatalysis

      Yasuhisa Asano

    Synthetic applications

    10. Chiral Heteroatom Containing Compounds

      Piotr Kiełbasinìski

    11. Synthesis of Boron Related Compounds for Medicinal Application Using Lipase

      Shuichi Mori

    12. Synthesis of Fluorinated Compounds Using Lipase

      Yumiko Takagi

    13. Site-selective lipase-catalyzed acylation and deacylation in the synthesis of valuable carbohydrates and flavonoids from naturally abundant starting materials

      Takeshi Sugai

    14. Synthesis of Biologically Active Compounds Using Biocatalysis

      Takashi Kitayama

    15. Synthesis of Fragrance Using Lipase

      Masashi Kawasaki

    16. Dynamic Kinetic Resolution

      Shuji Akai

    17. Industrial Biocatalysis

      Yoshihiko Hirose

    Indispensable discipline for the biocatalysis development

    18. Metagenomics for Improved Biocatalysis

      Nobuya Itoh

    19. Modeling Biocatalysts

      Daron Standley

    20. X-Ray Crystallographic Structure Determination

      Toshiya Senda and Miki Senda

Product details

  • No. of pages: 460
  • Language: English
  • Copyright: © Elsevier 2017
  • Published: August 11, 2017
  • Imprint: Elsevier
  • Hardcover ISBN: 9780444637437
  • eBook ISBN: 9780444637505

About the Editor

Tomoko Matsuda

Tomoko Matsuda is an Associate Professor at the School of Life Science and Technology, Tokyo Institute of Technology. For 20 years, her research has been focused on the organic synthesis with enzymes, biocatalysis, and particularly the study of enzymatic reactions in a non-aqueous solvent. Her group has achieved the waste-minimization in large-scale production of chiral compounds with a flow system using liquid and supercritical carbon dioxide as a solvent and an immobilized lipase as a catalyst.

Affiliations and Expertise

Tokyo Institute of Technology, Department of Bioengineering, Yokohama, Japan

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