Fundamentals of Toxicologic Pathology

Fundamentals of Toxicologic Pathology

2nd Edition - November 16, 2009

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  • Editors: Matthew Wallig, Wanda Haschek, Colin Rousseaux
  • Hardcover ISBN: 9780123704696
  • eBook ISBN: 9780080919324

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Toxicologic pathology integrates toxicology and the disciplines within it (such as biochemistry, pharmacodynamics and risk assessment) to pathology and its related disciplines (such as physiology, microbiology, immunology, and molecular biology). Fundamentals of Toxicologic Pathology Second Edition updates the information presented in the first edition, including five entirely new chapters addressing basic concepts in toxicologic pathology, along with color photomicrographs that show examples of specific toxicant-induced diseases in animals. The current edition also includes comparative information that will prove a valuable resource to practitioners, including diagnostic pathologists and toxicologists.

Key Features

  • 25% brand new information, fully revised throughout
  • New chapters: Veterinary Diagnostic Toxicologic Pathology; Clinical Pathology; Nomenclature: Terminology for Morphologic Alterations; Techniques in Toxicologic Pathology
  • New color photomicrographs detailing specific toxicant-induced diseases in animals
  • Mechanistic information integrated from both toxicology and pathology discussing basic mechanisms of toxic injury and morphologic expression at the subcellular, cellular, and tissue levels


Toxicologists, pathologists, medical libraries/institutions

Table of Contents

  • 1. Principles of Toxicology 
    2. Manifestations of Toxic Cell Injury -- Cell Injury/Death and Chemical Carcinogenesis
    3. Clinical Pathology
    4. Nomenclature-- Terminology for Morphologic Alterations
    5. Techniques in Toxicologic Pathology
    6. Respiratory System
    7. Skin and Oral Mucosa
    8. Gastrointestinal Tract
    9. Liver
    10. Pancreas
    11. Kidney and Lower Urinary Tract
    12. Cardiovascular and Skeletal Muscle Systems
    13. Bones
    14. Nervous System
    15. Immune System
    16. Hematopoietic System
    17. Endocrine System
    18. Male Reproduction
    19. Female Reproduction
    20. Developmental Toxicology

Product details

  • No. of pages: 714
  • Language: English
  • Copyright: © Academic Press 2009
  • Published: November 16, 2009
  • Imprint: Academic Press
  • Hardcover ISBN: 9780123704696
  • eBook ISBN: 9780080919324

About the Editors

Matthew Wallig

Professor Wallig is a Diplomate of the American College of Veterinary Pathologists. He is Professor Emeritus in the Department of Pathobiology, College of Veterinary Medicine, the Department of Food Science and Human Nutrition, as well as the Division of Nutritional Sciences at the University of Illinois. His research has focused on the chemoprotective properties and mechanisms of phytochemicals in the diet, in particular those in cruciferous vegetables and soy, and the pathophysiology of pancreatic injury.

Affiliations and Expertise

Professor Emeritus, Department of Veterinary Pathobiology, College of Veterinary Medicine University of Illinois at Urbana-Champaign, Urbana, Illinois, USA

Wanda Haschek

Professor Haschek-Hock has served as president of the Society of Toxicologic Pathology and the Society of Toxicology’s Comparative and Veterinary Specialty Section, as well as Councilor of the American College of Veterinary Pathologists, board member of the American Board of Toxicology; as Associate Editor for Toxicological Sciences and for Toxicologic Pathology; as Editorial Board member for Fundamental and Applied Toxicology, Veterinary Pathology and Toxicologic Pathology. She has served as a member on the USFDA Veterinary Medicine Advisory Committee for the Center for Veterinary Medicine, the EPA’s FIFRA Science Advisory Panel, and National Academy of Sciences Committee. She currently serves on the Board of Directors of the C.L. Davis Foundation for the Advancement of Veterinary and Comparative Pathology. She was awarded the Society of Toxicologic Pathology’s Achievement Award in 2007 and the Midwest Regional Chapter – Society of Toxicology’s Kenneth DuBois Award in 2011. -Diplomate of the American College of Veterinary Pathologists (ACVP) -Diplomate of the American Board of Toxicology (ABT) -Fellow of the International Academy of Toxicologic Pathologists (FIATP)

Affiliations and Expertise

University of Illinois at Urbana-Champaign

Colin Rousseaux

Professor Rousseaux is a Fellow of the Royal College of Pathology, Diplomate of the American Board of Toxicology, Fellow of the Academy of Toxicological Sciences, and Fellow of the International Academy of Toxicologic Pathology. He is Professor (Adjunct) in the Department of Pathology and Laboratory Medicine, Faculty of Medicine, University of Ottawa, Canada. He has 35 years of experience in comparative and toxicologic pathology with a research focus on herbal remedies, fetal development and teratology, and environmental pollutants. He has described, investigated, and evaluated numerous toxicologic pathology issues associated with pharmaceutical, pesticides, and agrochemicals. He has served on the editorial board of Toxicologic Pathology. He is a former president of the Society of Toxicologic Pathology

Affiliations and Expertise

Adjunct Professor, Department of Pathology and Laboratory Medicine, University of Ottawa Principal, Colin Rousseaux and Associates, Canada

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