
Fundamentals of Nanotoxicology
Concepts and Applications
Description
Key Features
- Provides types, classifications, sources, properties, the application of nanomaterials, and impacts on humans and the environment
- Includes risk, hazard and exposure assessments, risk characterizations and testing strategies
- Discusses mechanisms of toxicity, organ and non-organ directed toxicity, and mammalian toxicology of nanomaterials
Readership
Advanced undergraduate, graduate students, PhD students, and professors in toxicology, nanotechnology, and material science. Researchers entering or learning a new or adjacent (interdisciplinary) research area in toxicology, nanotechnology, and material science
Table of Contents
- Cover image
- Title page
- Table of Contents
- Copyright
- About the author
- Preface
- Disclaimer
- Chapter 1. Introduction, historical glimpse and regulations
- Abstract
- 1.1 Introduction
- 1.2 Key points
- 1.3 Overview
- 1.4 Historical oversight
- 1.5 Terminology for nanomaterials
- 1.6 Overview of regulations
- 1.7 Ultrafine particles versus nanomaterials, an overview
- 1.8 Future of nanotoxicology
- Reference
- Further reading
- Chapter 2. Types, classification, and applications
- Abstract
- 2.1 Introduction
- 2.2 Key points
- 2.3 Overview
- 2.4 Nanomaterials and bulk materials
- 2.5 Behavior of nanoparticles versus larger particles
- 2.6 Categories of nanomaterials
- 2.7 Origin
- 2.8 Dimensionality (geometry)
- 2.9 Morphology
- 2.10 Chemical composition
- 2.11 Uniformity and agglomeration
- 2.12 Nanocomposites
- 2.13 Hybrid nanomaterials
- 2.14 Applications
- 2.15 Concluding remarks
- References
- Further reading
- Chapter 3. Sources and properties
- Abstract
- 3.1 Introduction
- 3.2 Key points
- 3.3 Overview
- 3.4 Properties
- 3.5 Sources
- Further reading
- Chapter 4. Synthesis, characterization and uses
- Abstract
- 4.1 Introduction
- 4.2 Key points
- 4.3 Overview
- 4.4 Synthesis
- 4.5 Production approaches
- 4.6 Hybrid nanomaterials
- 4.7 Magnetic nanoparticles
- 4.8 Key Issues in the fabrication
- 4.9 Detection, characterization, and isolation
- References
- Further reading
- Chapter 5. Health and safety assessment
- Abstract
- 5.1 Introduction
- 5.2 Key points
- 5.3 Overview
- 5.4 Sustainable nanotechnology
- 5.5 Registration, evaluation, authorization, and restriction of chemicals regulation
- 5.6 Testing strategies
- 5.7 Risk assessment
- 5.8 Challenges
- 5.9 Conclusion
- References
- Further reading
- Chapter 6. Mechanism of nanotoxicity
- Abstract
- 6.1 Introduction
- 6.2 Key points
- 6.3 Overview
- 6.4 Terminology
- 6.5 Entry sites and uptake
- 6.6 Elimination of nanomaterials
- 6.7 Cell membrane processes
- 6.8 Processes of nanotoxicity
- 6.9 Mechanistic pathways of cellular dysfunction
- 6.10 Concluding remarks
- References
- Further reading
- Chapter 7. Organ and nonorgan-directed toxicity
- Abstract
- 7.1 Introduction
- 7.2 Key points
- 7.3 Overview
- 7.4 Nanoparticles versus larger particles
- 7.5 Factors affecting nanotoxicity
- 7.6 Portals of entry
- 7.7 Overview of behavior
- 7.8 Potential adverse effects of nanomaterials
- 7.9 Organ nanotoxicity
- 7.10 Nontarget-directed toxicity
- 7.11 Conclusion
- References
- Further reading
- Chapter 8. Biomedical applications
- Abstract
- 8.1 Introduction
- 8.2 Key points
- 8.3 Overview
- 8.4 Nanomaterials
- 8.5 Advantages and limitations
- 8.6 Applications
- 8.7 Drug delivery
- 8.8 Bioimaging
- 8.9 Photoablation therapy (photodynamic and photothermal therapy)
- 8.10 Biosensors
- 8.11 Tissue engineering
- 8.12 Diseases and disorders
- 8.13 Trojan horse mechanism
- 8.14 Interactions/biocompatibility
- 8.15 Toxicity and potential risks
- 8.16 Conclusions
- References
- Further reading
- Chapter 9. Food and food packaging
- Abstract
- 9.1 Introduction
- 9.2 Key points
- 9.3 Overview
- 9.4 Characteristics and types of nanoparticles
- 9.5 Food sectors
- 9.6 Food matrix effects
- 9.7 Nanotoxicology mechanisms
- 9.8 Potential risks and regulations
- 9.9 Conclusion
- References
- Further reading
- Chapter 10. Sustainable agriculture
- Abstract
- 10.1 Introduction
- 10.2 Key points
- 10.3 Overview
- 10.4 Plant growth and agronomic yields
- 10.5 Nanomaterials
- 10.6 Uses and applications
- 10.7 Pesticides, fertilizers, and nanobiosensors
- 10.8 Exposure, fate, and behavior
- 10.9 Interactions
- 10.10 Phytotoxicity
- 10.11 Hazard potentials
- 10.12 Current status and challenges
- Further reading
- Chapter 11. Environmental and eco-system
- Abstract
- 11.1 Introduction
- 11.2 Key points
- 11.3 Overview
- 11.4 Types of nanoparticles
- 11.5 Pathways in the environment
- 11.6 Fate and behavior in environmental
- 11.7 Fate and behavior in ecosystems
- 11.8 Eco-toxicity
- 11.9 Interactions with other pollutants
- 11.10 Food chain effects and secondary poisoning
- 11.11 Hazard evaluation
- 11.12 Environmental risk assessment strategy
- 11.13 Comments and remarks
- References
- Further reading
- Index
Product details
- No. of pages: 246
- Language: English
- Copyright: © Academic Press 2022
- Published: April 27, 2022
- Imprint: Academic Press
- eBook ISBN: 9780323906906
- Paperback ISBN: 9780323903998
About the Author
P.K. Gupta
In addition to this Dr Gupta has also been biographer in several WHO's WHO from all over the world including Marquis WHOs WHO (USA), IBC (UK) and other leading publications of the World. .At present Dr Gupta is a Director of Toxicology Consultant Group, Patron and Founder President of the Society of Toxicology of India, and President of the Academy of Sciences for Animal Welfare.
Affiliations and Expertise
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