Key Features

  • A full-color, 4-page insert shows realistic images of the output for many molecular tests.
  • Learning Objectives open each chapter with an overview of what you should achieve.
  • Key Words are listed and defined at the beginning of each chapter, and are bolded in the text.
  • Review Questions at the end of every chapter let you measure your comprehension.
  • Advanced Concepts are included, but set apart from the rest of the text, for students who want a higher level of learning.
  • Ethics boxes address ethical issues, allowing you to apply your knowledge to real-life scenarios.
  • A glossary of all key words may be easily accessed in the back of the book.

Table of Contents

I. Principles

1. Principles of Molecular Biology

2. Genomes and Nucleic Acid Alterations

II. Techniques and Instrumentation

3. Specimen Collection and Processing

4. Nucleic Acid Isolation

5. Nucleic Acid Techniques

6. Miniaturization: DNA Chips and Devices

7. Design and Operation of a Molecular Diagnostics Laboratory

8. Introduction to Evidence-Based Molecular Diagnostics

III. Applications

9. Inherited Diseases

10. Identity Assessment

11. Molecular Methods in Diagnosis and Monitoring of Infectious Diseases

12. Pharmacogenetics

13. Molecular Genetics in Diagnosis of Human Cancers

IV. Appendix

14. Reference Information

Answers to Review Questions

Glossary

Details

No. of pages:
288
Language:
English
Copyright:
© 2007
Published:
Imprint:
Saunders
Print ISBN:
9781416037378
Electronic ISBN:
9781437719345

About the authors

David Bruns

Affiliations and Expertise

Professor of Pathology, University of Virginia School of Medicine, Director of Clinical Chemistry and Associate Director of Molecular Diagnostics, University of Virginia Health System, Charlottesville, VA, and Former Editor, Clinical Chemistry, Washington, DC

Edward Ashwood

Affiliations and Expertise

Professor of Pathology, University of Utah School of Medicine, and President and CEO, ARUP Laboratories, Salt Lake City, UT

Carl Burtis

Affiliations and Expertise

Health Services Division, Oak Ridge National Laboratory, Oak Ridge, TN, and Clinical Professor of Pathology, University of Utah School of Medicine, Salt Lake City, UT