Fundamentals of Biochemical Pharmacology explains the molecular aspects of drugs and the changes in bio-chemical systems. The cellular movements that result from such changes are also evaluated. Biochemical lesion is extensively defined in the book. A discussion on electromagnetic radiation is also provided. A chapter of the book is devoted to the principles of electronic and nuclear magnetic resonance. The principles and applications of mass spectrometry and combined gas chromatography are then discussed. The scientific advances made with the use of immunological methods are the focus of a section of the book. Another section provides an introduction to the kinetic properties of reactions made by enzymes. The process called homogenization is clearly explained along with a discussion on the use of electron microscopy. Autoradiography shows the distribution of compounds at the subcellular level. The theoretical background of molecular spectroscopy is presented completely. The book is intended for chemists, biochemists, physicists, micro-biologists, zoologists, and botanists .
Preface List of Authors Section A: Outlines of Methods Physicochemical Methods 1 Introduction to Optical Methods2. Electronic and Nuclear Magnetic Resonances 3 Mass Spectrometry 4 Isotopic Methods and Activation Analysis 5 Isolation and Purification Procedures 6 Immunochemistry and Radioimmunochemistry 7. Introduction to Enzyme Kinetics 8 Centrifugation of Subcellular Components Histological Methods 9 Electron Microscopy 10 Histoautoradiography 11 Biochemical and Pharmacological Aspects of Histochemistry Physiological Methods 12 Animals and Isolated Organs 13 Electrophysiological Methods 14 Behavioral Techniques
Section B: Biochemical Pharmacology 1 The Concept of The Biochemical Lesion 2 Functions of Subcellular Structures 2.1. Bacterial Walls and Membranes 2.2. Mitochondria 2.3. Drugs and Lysosomes 3 Transfer of Ions and Molecules Across Cellular Membranes 4 Pharmacokinetics 5 Synaptic Vesicles, Specific Granules, Autopharmacology 5.1. Cholinergic Transmissions 5.2. Adrenergic Transmission 5.3. Indolealkylamines 5.4. Histamine 5.5. Prostaglandins 5.6. Polypeptides 6 Drug-Receptor Interactions 7 Chelating Agents 8 Effects of Drugs on Structure, Biosynthesis and Catabolism of Nucleic Acids, Proteins, Carbohydrates and Lipids 8.1. Nucleic Acids and Proteins 8.2. Carbohydrates 8.3. Drugs Acting on Blood Lipids 9 Biotransformation of Drugs 10 Pharmacogenetics 11 Comparative Pharmacology Index
- No. of pages:
- © Pergamon 1971
- 1st January 1971
- eBook ISBN: