Fundamentals of Biochemical Pharmacology

Fundamentals of Biochemical Pharmacology

Pergamon International Library of Science, Technology, Engineering and Social Studies

1st Edition - January 1, 1971

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  • Editor: Z. M. Bacq
  • eBook ISBN: 9781483181622

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Fundamentals of Biochemical Pharmacology explains the molecular aspects of drugs and the changes in bio-chemical systems. The cellular movements that result from such changes are also evaluated. Biochemical lesion is extensively defined in the book. A discussion on electromagnetic radiation is also provided. A chapter of the book is devoted to the principles of electronic and nuclear magnetic resonance. The principles and applications of mass spectrometry and combined gas chromatography are then discussed. The scientific advances made with the use of immunological methods are the focus of a section of the book. Another section provides an introduction to the kinetic properties of reactions made by enzymes. The process called homogenization is clearly explained along with a discussion on the use of electron microscopy. Autoradiography shows the distribution of compounds at the subcellular level. The theoretical background of molecular spectroscopy is presented completely. The book is intended for chemists, biochemists, physicists, micro-biologists, zoologists, and botanists .

Table of Contents

  • Preface

    List of Authors

    Section A: Outlines of Methods

    Physicochemical Methods

    1 Introduction to Optical Methods

    2. Electronic and Nuclear Magnetic Resonances

    3 Mass Spectrometry

    4 Isotopic Methods and Activation Analysis

    5 Isolation and Purification Procedures

    6 Immunochemistry and Radioimmunochemistry

    7. Introduction to Enzyme Kinetics

    8 Centrifugation of Subcellular Components

    Histological Methods

    9 Electron Microscopy

    10 Histoautoradiography

    11 Biochemical and Pharmacological Aspects of Histochemistry

    Physiological Methods

    12 Animals and Isolated Organs

    13 Electrophysiological Methods

    14 Behavioral Techniques

    Section B: Biochemical Pharmacology

    1 The Concept of The Biochemical Lesion

    2 Functions of Subcellular Structures

    2.1. Bacterial Walls and Membranes

    2.2. Mitochondria

    2.3. Drugs and Lysosomes

    3 Transfer of Ions and Molecules Across Cellular Membranes

    4 Pharmacokinetics

    5 Synaptic Vesicles, Specific Granules, Autopharmacology

    5.1. Cholinergic Transmissions

    5.2. Adrenergic Transmission

    5.3. Indolealkylamines

    5.4. Histamine

    5.5. Prostaglandins

    5.6. Polypeptides

    6 Drug-Receptor Interactions

    7 Chelating Agents

    8 Effects of Drugs on Structure, Biosynthesis and Catabolism of Nucleic Acids, Proteins, Carbohydrates and Lipids

    8.1. Nucleic Acids and Proteins

    8.2. Carbohydrates

    8.3. Drugs Acting on Blood Lipids

    9 Biotransformation of Drugs

    10 Pharmacogenetics

    11 Comparative Pharmacology


Product details

  • No. of pages: 674
  • Language: English
  • Copyright: © Pergamon 1971
  • Published: January 1, 1971
  • Imprint: Pergamon
  • eBook ISBN: 9781483181622

About the Editor

Z. M. Bacq

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