Frontiers in Colorectal Disease

Frontiers in Colorectal Disease presents a compilation of articles from the international conference titled ‘Frontiers in Colorectal Disease’. It discusses the aspects of functional disorders, neoplastic disease and inflammatory bowel disease. It addresses the practical management of a variety of disorders of the colon, rectum, and anus. Some of the topics covered in the book are the basis of functional intestinal symptoms; nervous control of the gut; physiological reactions of the gastrointestinal tract to stress; visceral pain; mechanisms of flatulence and diarrhoea; pathophysiology of constipation; Arbuthnot Lane’s disease; and megacolon in adults. The results of surgical treatment of constipation are fully covered. The anorectal incontinence of electrophysiological tests is discussed in detail. The text describes in depth the risk factors in childbirth causing damage to the pelvic floor innervation. A retrospective study of the results of post-anal repair is presented completely. A chapter is devoted to the gracilis muscle transposition for anal incontinence. Another section focuses on the magnitude of risk for cancer in patients with colorectal adenomas. The book can provide useful information to doctors, surgeons, students, and researchers.

Contents

Introduction

Functional Disorders

Symposium I—The Basis of Functional Intestinal Symptoms

Nervous Control of the Gut

Physiological Reactions of the Gastrointestinal Tract To Stress

Visceral Pain

Mechanisms of Flatulence and Diarrhea

Symposium II—Constipation

Pathophysiology of Constipation

Arbuthnot Lane's Disease: Chronic Intestinal Stasis

Megacolon in Adults

Constipation: Results of Surgical Treatment

Symposium III—Anorectal Incontinence

Anorectal Incontinence: Electrophysiological Tests

Risk Factors in Childbirth Causing Damage to the Pelvic Floor Innervation

Results of Postanal Repair: A Retrospective Study

Sphincter Injuries: Indications For, and Results of Sphincter Repair

Gracilis Muscle Transposition For Anal Incontinence: Late Results

Neoplastic Disease

Symposium IV—Adenoma Surveillance

Magnitude of Risk For Cancer in Patients with Colorectal Adenomas

Polyp Follow-Up: How, Who For and How Often?

Follow-Up After Removal of Colorectal Adenomas and Radical Surgery For Colorectal Carcinomas

Symposium V—Adenomatous Polyposis

The Rectum in Adenomatous Polyposis: The St. Mark's Policy

Familial Polyposis

HLA and Genetic Marker Studies in Adenomatous Polyposis

Symposium VI—Carcinogenesis

Experimental Intestinal Carcinogenesis

Cancer of the Large Bowel: Human Carcinogenesis

Genetic Aspects of Carcinogenesis

Symposium VII—Tumour Markers

Antibody Markers

Radioimmunoscintigraphy of Cancer

Carcinoembryonic Antigen and Recurrent Colorectal Cancer

Symposium VIII—Staging of Colorectal Cancer

Clinicopathological Staging of Colorectal Cancer: Has The Time Arrived?

Imaging

Clinical Local Staging of Rectal Cancer

Symposium IX—Local Excision For Colorectal Cancer

Histological Criteria For Local Excision

Indications For Local Excision of Rectal Cancer

Techniques of Local Surgical Excision For Rectal Carcinoma

Symposium X—Radiotherapy in Rectal Cancer

Adjuvant Radiotherapy in Rectal Cancer: The MRC Trials

Pre-Operative Radiotherapy in Operable Rectal Cancer: Interim Report of A Trial Carried Out By The Rectal Cancer Group

Radiation Therapy and Rectal Carcinoma: The Princess Margaret Hospital Experience

Symposium XI—Screening in Colorectal Cancer

Faecal Occult Blood Testing: Sensitivity and Specificity

A Control Trial of Faecal Occult Blood Screening For Colorectal Cancer: 2-Year Results

The Feasibility of Large Scale Population Screening

Dark Red Bleeding As A Marker For Large Bowel Neoplasms: A Pilot Study

Inflammatory Bowel Disease

Symposium XII—Ulcerative Colitis: Sphincter-Saving Operations

Ileorectal Anastomosis

Restorative Proctocolectomy with Ileal Reservoir

Ileal 'J' Pouch-Anal Anastomosis

Symposium XIII—Ulcerative Colitis: Dysplasia and Cancer Risk

Dysplasia and Cancer in Inflammatory Bowel Disease

The Cancer Risk in Ulcerative Colitis: Surveillance Or Surgery

Symposium XIV—Crohn's Disease: Special Problems

Crohn's Disease in Childhood

Crohn's Disease in Young People

The Short Bowel

The Management of Internal Fistulae in Crohn's Disease

Anal Lesions in Crohn's Disease

Original Papers

Epidermoid Cancer of the Anus

Continuing Experience with Single Layer Appositional Anastomosis in The Large Bowel

Effect of Adjuvant Chemo- Or Immunotherapy On The Prognosis of Colorectal Cancer Operated For Cure

Evacuation Proctography in Obstructed Defaecation and Rectal Intussuception

Intrarectal Ultrasound and Computed Tomography in Pre- and Postoperative Assessment of Patients with Rectal Cancer

Abstracts for Free Papers

Abstracts for Posters

Index