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Topics in Pharmacy, Volume 1: Formulation Factors in Adverse Reactions focuses on the important aspect of drug therapy—the nature of the dosage form or its ingredients that adversely influence therapeutic outcome. This book discusses the adverse reactions to formulation excipients, immunological basis of allergic reactions to drugs, and adverse reactions to parenteral medication. The influence of the shape and size of solid medicines on esophageal transit, and effects of the physical characteristics of formulations on adverse reactions are also deliberated. This volume is intended for senior undergraduate and postgraduate students in pharmacy, medicine, nursing and allied health sciences, and practitioners in the field of drug therapy.
List of Contributors
1 Adverse Reactions to Excipients in Pharmaceutical Formulations
Introduction: Excipients are Not Inactive
Spectrum and Incidence of Excipient Reactions
Sugars, Sweeteners and Flavors
Components of Ointments, Creams and Other Topical
Problems and Possible Solutions
Recommended Further Reading
2 Drug Allergy: Chemical and Pharmaceutical Aspects
Immunochemical Mechanisms of Drug Allergy
Routes Of Formation of Antigens from Drugs
3 Adverse Reactions to Parenterals
Particulates as a Cause of Adverse Reactions to Parenterals
Administration of Parenterals
4 Adverse Reactions to the Transit of Oral Dosage Forms
Drug-Induced Oesophageal Ulceration
Factors Influencing Oesophageal Transit
Drug Absorption After Delayed Oesophageal Transit
5 Physical Properties of Formulations and Adverse Reactions to Medicines
Oral Dosage Forms
- No. of pages:
- © Butterworth-Heinemann 1990
- 16th February 1990
- eBook ISBN:
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