Flow Cytogenetics
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This is the first book to be devoted entirely to the application and development of flow techniques in cytogenetics. It provides comprehensive information on the use of flow cytometry and sorting for chromosome classification and purification. Cytogenetics and molecular biologists will find this book an invaluable reference source.
Key Features
- Practical details for the preparation and analysis of chromosomes using flow cytometry
- Flow karyotyping for sensitive rapid analysis of chromosome normality and the detection of aberrant chromosomes
- Flow sorting as a source of chromosome-specific DNA for gene mapping and recombinant DNA libraries
- Construction and current status of chromosome-specific recombinant DNA libraries
Readership
Molecular biologists, cell biologists, and geneticists
Table of Contents
- Human Chromosome Analysis by Flow Cytometry. Instrumentation for Chromosome Analysis and Sorting. Cell Culture for Chromosome Isolation. Chromosome Isolation Procedures. DNA Stains as Cytochemical Probes for Chromosomes. Methods for Estimating Components of Multipeaked Flow Histograms. Univariate Flow Karyotype Analysis. Bivariate Flow Karyotyping. Relation between Radiation-Induced Flow Karyotype Change
Product details
- No. of pages: 312
- Language: English
- Copyright: © Academic Press 1989
- Published: November 23, 1989
- Imprint: Academic Press
- eBook ISBN: 9780080984520
About the Editor in Chief
Johan Ploem
Affiliations and Expertise
University of Leiden, The Netherlands
About the Series Volume Editor
Joe Gray
Affiliations and Expertise
Lawrence Livermore National Laboratory, Livermore, California, U.S.A.