Flow Cytogenetics

Flow Cytogenetics

1st Edition - November 23, 1989

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  • Editor-in-Chief: Johan Ploem
  • eBook ISBN: 9780080984520

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Description

This is the first book to be devoted entirely to the application and development of flow techniques in cytogenetics. It provides comprehensive information on the use of flow cytometry and sorting for chromosome classification and purification. Cytogenetics and molecular biologists will find this book an invaluable reference source.

Key Features

  • Practical details for the preparation and analysis of chromosomes using flow cytometry
  • Flow karyotyping for sensitive rapid analysis of chromosome normality and the detection of aberrant chromosomes
  • Flow sorting as a source of chromosome-specific DNA for gene mapping and recombinant DNA libraries
  • Construction and current status of chromosome-specific recombinant DNA libraries

Readership

Molecular biologists, cell biologists, and geneticists

Table of Contents

  • Human Chromosome Analysis by Flow Cytometry. Instrumentation for Chromosome Analysis and Sorting. Cell Culture for Chromosome Isolation. Chromosome Isolation Procedures. DNA Stains as Cytochemical Probes for Chromosomes. Methods for Estimating Components of Multipeaked Flow Histograms. Univariate Flow Karyotype Analysis. Bivariate Flow Karyotyping. Relation between Radiation-Induced Flow Karyotype Change

Product details

  • No. of pages: 312
  • Language: English
  • Copyright: © Academic Press 1989
  • Published: November 23, 1989
  • Imprint: Academic Press
  • eBook ISBN: 9780080984520

About the Editor in Chief

Johan Ploem

Affiliations and Expertise

University of Leiden, The Netherlands

About the Series Volume Editor

Joe Gray

Affiliations and Expertise

Lawrence Livermore National Laboratory, Livermore, California, U.S.A.

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