Description

Fertilization provides in-depth reviews of individual research topics, while emphasizing key concepts and the significance of findings within other fields. The author identifies essential questions to be answered by future research. Fertilization broadly covers the many molecular and cellular events of animal fertilization and includes a section on unique problems and potential applications of fertilization research.

Key Features

Key Features * Provides in-depth reviews of individual research topics * Emphasizes key concepts and significance of findings to other fields * Broadly covers the many molecular and cellular events of animal fertilization * Includes a section on unique problems and potential applications of fertilization research * Identifies essential questions to be answered by future research

Readership

Reproductive endocrinologists, biotechnology industry, OB/GYNs, infertility/fertility and contraception specialists.

Table of Contents

Contributors Preface Acknowledgments Section I Fertilization Events 1 Gamete Transport I. Introduction II. Sperm Transport III. Oocyte Transport IV. A Model for Gamete Transport References 2 Sperm Motility ActIVation and Chemoattraction I. Introduction II. Assays III. Motility Acquisition IV. Motility ActIVation V. Motility Modulation in the Female ReproductIVe Tract VI. Egg-associated Motility Stimulation VII. Chemoattraction VIII. Concluding Remarks References 3 Capacitation I. Introduction II. initiation, Propagation, and Termination of Capacitation III. Molecular Mechanism of Capacitation IV. Physiological Mechanism and Role of Capacitation V Conclusions References 4 Function of the Egg's Extracellular Matrix I. Introduction II. The Cumulus Oophorus III. The Zona Pellucida IV. Future Directions References 5 Sperm Adhesion to the Extracellular Matrix of the Egg I. Introduction II. Basic Biology of Sperm-Eem Adhesion III. Identification of Eem Adhesion Molecules IV. Future Prospects and Directions References 6 Signal Transduction Mechanisms Regulating Sperm Acrosomal Exocytosis I. Introduction II. Biogenesis and Morphology of the Acrosome III. Biological Significance of Acrosomal Exocytosis IV. Physiological Site of Acrosomal Exocytosis V. The Zona Pellucida and Progesterone as Physiological Inducers of Acrosomal Exocytosis VI. Sperm-associated Receptor/Binding Proteins for the Zona Pellucida and Progesterone VII. Signal Transduction Mechanisms Mediating the Effects of the Zona Pellucida and Progesterone References

Details

No. of pages:
427
Language:
English
Copyright:
© 2002
Published:
Imprint:
Academic Press
eBook ISBN:
9780080531649
Print ISBN:
9780123116291

About the authors

Daniel Hardy

Affiliations and Expertise

Texas Tech University Health Sciences Center, Lubbock, U.S.A.

D. Garbers

Affiliations and Expertise

University of Texas Southwestern Medical Center, Dallas, U.S.A.