Description

Neuromodulation is an emerging field that explores the use of electrical, chemical, and mechanical interventions to heal neurological deficits. Such neurostimulation has already shown great promise with disorders and diseases such as chronic pain, epilepsy, and Parkinson’s disease. This is the first concise reference covering all of the basic principles of neuromodulation in a single affordable volume for neuro-residents, fellows, and basic clinical practitioners, edited by two prominent clinical experts in the field.

This volume emphasizes essential observations from all of the important clinical phases involved in any neuromodulation: targeting, intraoperative assessment, programming, complications, and complication avoidance. There are commonalities to all neuromodulation procedures that must be brought to the forefront to form a cohesive presentation of neuromodulation, and such emphasis will give readers a more solid grounding in the fundamentals needed to embrace this field as a cohesive clinical entity.

Key Features

  • Chapters offer point-counterpoint commentary for varied perspectives
  • Appendix distills current guidelines in easy, accessible format
  • Chapters follow story of patient care, effectively emphasizing general principles with supporting examples
  • Offers outstanding scholarship, with over 20% of chapters involving international contributors

Readership

Academic clinicians in neurophysiology, neurological diseases, behavioral neuroscience, sensory neuroscience, neuroanatomy and neurosurgery; biomedical engineers looking to understand the clinical aspects of neuro-therapies

Table of Contents

Contributors

Introduction

Chapter 1. The Neuromodulation Approach

Chapter 2. Cerebral – Surface

Chapter 3. Cerebral – Deep

Chapter 4. Spinal – Extradural

Chapter 5. Peripheral Nerve

Chapter 6. The Electrode – Materials and Configurations

Chapter 7. The Electrode – Principles of the Neural Interface

Chapter 8. The Electrode – Principles of the Neural Interface

Chapter 9. Device Materials, Handling, and Upgradability

Chapter 10. Electronics

Chapter 11. Power

Chapter 12. Surgical Techniques

Chapter 13. Trials and Their Applicability

Chapter 14. Limiting Morbidity

Chapter 15. Intraoperative Evaluation

Chapter 16. Programming – DBS Programming

Chapter 17. Programming – SCS

Chapter 18. Safety Concerns and Limitations

Chapter 19. Expectations and Outcomes

Chapter 20. Neuromodution Perspectives

Appendix

Index

Details

No. of pages:
504
Language:
English
Copyright:
© 2011
Published:
Imprint:
Academic Press
Electronic ISBN:
9780123814104
Print ISBN:
9780123814098

About the editors

Jeffrey Arle

Jeff Arle, MD, PhD, FAANS Dr. Arle is currently the Associate Chief of Neurosurgery at Beth Israel Deaconess Medical Center in Boston, the Chief of Neurosurgery at Mt. Auburn Hospital in Cambridge, and an Associate Professor of Neurosurgery at Harvard Medical School. He received his BA in Biopsychology from Columbia University in 1986 and his MD and PhD from the University of Connecticut in 1992. His dissertation work for his doctorate in Biomedical Sciences was in computational modeling in the Cochlear Nucleus. He then went on to do a residency in neurosurgery at the University of Pennsylvania, incorporating a double fellowship in movement disorder surgery and epilepsy surgery under Drs. Patrick Kelly, Ron Alterman, and Werner Doyle, finishing in 1999. He edited the companion text Essential Neuromodulation with Dr. Shils, the first edition published by Elsevier in 2011. He has now practiced in the field of functional neurosurgery for 17 years and is experienced in all areas of neuromodulation from deep brain stimulators to vagus nerve, spinal cord, peripheral nerve, and motor cortex stimulators, contributing frequent peer-reviewed publications and numerous chapters to the literature on many aspects of the neuromodulation field. He currently serves as an associate editor at the journals Neuromodulation and Neurosurgery, is the co-chair of the Research and Scientific Policy Committee for the International Neuromodulation Society, and is on the Board of Directors for the International Society for Intraoperative Neurophysiology. His longstanding research interests are in the area of computational modeling in the understanding and improved design of devices used in neuromodulation treatments.

Jay Shils

Jay L. Shils, Ph.D., D.ABNM, FASNM, FACNS was most recently the director of intra-operative neurophysiology in the Department of Neurosurgery at the Lahey Hospital and Health System in Burlington, MA and an Associate Professor in the department of neurosurgery at the Tufts University School of Medicine. He received his Bachelor of Science degree in electrical engineering from Syracuse University, and both his masters and PhD in Bio-Engineering at The University of Pennsylvania using higher order signal extraction and processing techniques on human EEG data to investigate interactions in the visual system and study EEG in epilepsy. He began his work in the field of intraoperative neurophysiology in 1994 specializing in single unit recordings during surgery for movement disorders in the department of Neurology at the University of Pennsylvania School of medicine. Dr. Shils is presently the director of intraoperative neurophysiology at Rush University Medical Center and an associate professor in the department of anesthesiology. Dr. Shils’ research interests include investigating methods for improving real-time intraoperative neurophysiologic techniques as well as theoretical research into neuromodulation mechanisms of action. Dr. Shils has published over 30 peer reviewed papers and multiple chapters on intraoperative neurophysiologic surgical technique, post-operative management of movement disorders patients, and computational modeling as related to neuromodulation effects on various neural circuits. He co-edited two books: “Neurophysiology in Neurosurgery: A modern approach” with Dr. Vedran Deletis; and “Essential Neuromodulation” with Dr. Jeffrey E. Arle. Prior to going to graduate school Dr. Shils was an electrical engineer at the Electric Boat division of General Dynamics where he was involved in various modifications to existing electrical systems. Dr. Shils is the past President of the International Society for Intraoperative Monitoring and was the fo