Essential Human Virology - 1st Edition - ISBN: 9780128009475, 9780128011713

Essential Human Virology

1st Edition

Authors: Jennifer Louten
eBook ISBN: 9780128011713
Paperback ISBN: 9780128009475
Imprint: Academic Press
Published Date: 17th April 2016
Page Count: 344
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Description

Essential Human Virology is written for the undergraduate level with case studies integrated into each chapter. The structure and classification of viruses will be covered, as well as virus transmission and virus replication strategies based upon type of viral nucleic acid. Several chapters will focus on notable and recognizable viruses and the diseases caused by them, including influenza, HIV, hepatitis viruses, poliovirus, herpesviruses, and emerging and dangerous viruses.

Additionally, how viruses cause disease, or pathogenesis, will be highlighted during the discussion of each virus family, and a chapter on the immune response to viruses will be included. Further, research laboratory assays and viral diagnosis assays will be discussed, as will vaccines, anti-viral drugs, gene therapy, and the beneficial uses of viruses. By focusing on general virology principles, current and future technologies, familiar human viruses, and the effects of these viruses on humans, this textbook will provide a solid foundation in virology while keeping the interest of undergraduate students.

Key Features

  • Focuses on the human diseases and cellular pathology that viruses cause
  • Highlights current and cutting-edge technology and associated issues
  • Presents real case studies and current news highlights in each chapter
  • Features dynamic illustrations, chapter assessment questions, key terms, and summary of concepts, as well as an instructor website with lecture slides, test bank, and recommended activities

Readership

undergraduate students in biology, biotechnology, microbiology, medical technology, nursing, or molecular biology

Table of Contents

  • Preface
  • About the Author
  • Instructor Companion Website
  • Chapter 1. The World of Viruses
    • 1.1. The Importance of Studying Viruses
    • 1.2. Viruses Are Not Alive
    • 1.3. The Origin of Viruses
    • 1.4. The Discovery of Viruses
    • 1.5. Other Nonliving Infectious Agents
    • Summary of Key Concepts
    • Flash Card Vocabulary
    • Chapter Review Questions
  • Chapter 2. Virus Structure and Classification
    • 2.1. Common Characteristics of Viruses
    • 2.2. Structure of Viruses
    • 2.3. Virus Classification and Taxonomy
    • Summary of Key Concepts
    • Flash Card Vocabulary
    • Chapter Review Questions
  • Chapter 3. Features of Host Cells: Cellular and Molecular Biology Review
    • 3.1. The Basic Organization of the Cell
    • 3.2. The Plasma Membrane, Exocytosis, and Endocytosis
    • 3.3. The Cell Cycle
    • 3.4. The Central Dogma of Molecular Biology: DNA Replication
    • 3.5. The Central Dogma of Molecular Biology: RNA Transcription and Processing
    • 3.6. The Genetic Code
    • 3.7. The Central Dogma of Molecular Biology: Protein Translation
    • 3.8. Promotion of Viral Transcription and Translation Processes
    • Summary of Key Concepts
    • Flash Card Vocabulary
    • Chapter Review Questions
  • Chapter 4. Virus Replication
    • 4.1. Attachment
    • 4.2. Penetration
    • 4.3. Uncoating
    • 4.4. Replication
    • 4.5. Assembly
    • 4.6. Maturation
    • 4.7. Release
    • 4.8. Virus Growth Curves
    • Summary of Key Concepts
    • Flash Card Vocabulary
    • Chapter Review Questions
  • Chapter 5. Virus Transmission and Epidemiology
    • 5.1. Portals of Virus Entry
    • 5.2. Dissemination Within a Host
    • 5.3. Portals of Virus Exit
    • 5.4. Patterns of Infection
    • 5.5. Epidemiology
    • 5.6. Epidemiological Studies
    • Summary of Key Concepts
    • Flash Card Vocabulary
    • Chapter Review Questions
  • Chapter 6. The Immune Response to Viruses
    • 6.1. The Innate Immune System
    • 6.2. The Adaptive Immune System
    • 6.3. Viral Evasion of the Immune Response
    • Summary of Key Concepts
    • Flash Card Vocabulary
    • Chapter Review Questions
  • Chapter 7. Detection and Diagnosis of Viral Infections
    • 7.1. Collection and Transport of Clinical Specimens
    • 7.2. Virus Culture and Cell/Tissue Specimens
    • 7.3. Detection of Viral Antigens or Antiviral Antibodies
    • 7.4. Detection of Viral Nucleic Acids
    • Summary of Key Concepts
    • Flash Card Vocabulary
    • Chapter Review Questions
  • Chapter 8. Vaccines, Antivirals, and the Beneficial Uses of Viruses
    • 8.1. Vaccine Development
    • 8.2. Antivirals
    • 8.3. The Beneficial Uses of Viruses
    • Summary of Key Concepts
    • Flash Card Vocabulary
    • Chapter Review Questions
  • Chapter 9. Viruses and Cancer
    • 9.1. Properties of Cancerous Cells
    • 9.2. Control of the Cell Cycle
    • 9.3. Important Genes Involved in the Development of Cancer
    • 9.4. Oncogenic Viruses
    • Summary of Key Concepts
    • Flash Card Vocabulary
    • Chapter Review Questions
  • Chapter 10. Influenza Viruses
    • 10.1. Influenza Taxonomy and Types
    • 10.2. Clinical Course of Infection
    • 10.3. Molecular Virology
    • 10.4. Genetic Changes in the Influenza Genome
    • 10.5. Historical Influenza Antigenic Shifts
    • 10.6. Highly Pathogenic Avian Influenza
    • Summary of Key Concepts
    • Flash Card Vocabulary
    • Chapter Review Questions
  • Chapter 11. Human Immunodeficiency Virus
    • 11.1. History of HIV Infection
    • 11.2. Taxonomy and Origins of HIV
    • 11.3. Epidemiology of HIV/AIDS
    • 11.4. Clinical Progression of HIV/AIDS
    • 11.5. Molecular Virology and Replication of HIV-1
    • Summary of Key Concepts
    • Flash Card Vocabulary
    • Chapter Review Questions
  • Chapter 12. Hepatitis Viruses
    • 12.1. Clinical Course of Hepatitis Virus Infections
    • 12.2. Transmission and Epidemiology of Hepatitis Viruses
    • 12.3. Molecular Virology of the Hepatitis Viruses
    • Summary of Key Concepts
    • Flash Card Vocabulary
    • Chapter Review Questions
  • Chapter 13. Herpesviruses
    • 13.1. Herpesvirus Classification
    • 13.2. Clinical Conditions Caused by Herpesviruses
    • 13.3. Molecular Virology
    • 13.4. Latency
    • Summary of Key Concepts
    • Flash Card Vocabulary
    • Chapter Review Questions
  • Chapter 14. Poliovirus
    • 14.1. The Early Years of Poliovirus
    • 14.2. Clinical Course of Infection
    • 14.3. Poliovirus Replication
    • 14.4. Epidemiology and Worldwide Eradication Efforts
    • Summary of Key Concepts
    • Flash Card Vocabulary
    • Chapter Review Questions
  • Chapter 15. Poxviruses
    • 15.1. Taxonomy
    • 15.2. Clinical Course of Variola Infection
    • 15.3. Poxvirus Replication Cycle
    • 15.4. Eradication of Smallpox
    • Summary of Key Concepts
    • Flash Card Vocabulary
    • Chapter Review Questions
  • Chapter 16. Emerging and Reemerging Viral Diseases
    • 16.1. Factors Involved in the Emergence of Viral Infectious Diseases
    • 16.2. Notable Emerging/Reemerging Viral Diseases
    • Summary of Key Concepts
    • Flash Card Vocabulary
    • Chapter Review Questions
  • Appendix 1
  • Appendix 2
  • Index

Details

No. of pages:
344
Language:
English
Copyright:
© Academic Press 2017
Published:
Imprint:
Academic Press
eBook ISBN:
9780128011713
Paperback ISBN:
9780128009475

About the Author

Jennifer Louten

Jennifer Louten received her doctoral degree from Brown University Medical School, where she investigated the cellular targets of infection and the induction of type 1 interferons following infection with lymphocytic choriomeningitis virus. Dr. Louten is currently an associate professor of biology at Kennesaw State University, where she has served as a Teaching Fellow and developed courses in virology, biotechnology, immunology, and cell culture techniques. She is presently the biotechnology program coordinator and the director of a scholarship program sponsored by a National Science Foundation grant. She is the recipient of a Kennesaw State University Outstanding Early Career Faculty Award and the Student Government Association’s Faculty of the Year Award. Before becoming a professor, Dr. Louten performed research in drug discovery at Schering-Plough Biopharma (currently Merck Research Laboratories). She received her Bachelor of Science in biotechnology from the Rochester Institute of Technology.

Affiliations and Expertise

Associate Professor, Department of Molecular and Cellular Biology, Kennesaw State University, GA, USA