Esophageal Disease and the Role of the Microbiome

Esophageal Disease and the Role of the Microbiome

1st Edition - February 1, 2023

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  • Editor: David Johnson
  • Paperback ISBN: 9780323950701

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Esophageal Diseases and the Role of the Microbiome provides evidence on biomic influence in esophageal diseases. The book builds on the translational information on H pylori for ulcer disease as well as the explosive focus on biomic influence in virtually all areas of esophageal diseases. This important reference will help translational researchers by providing scientific understanding and hypothesis generation that is needed for furthering this field of study. It will also provide clinicians with disease management options for esophageal diseases (for GERD and PPI options/side effects) and present cutting-edge science to promote provider/patient understanding and options.

Key Features

  • Delivers a translational understanding of new paradigms for esophageal disease
  • Explains the effects of microbiome balance in the esophagus
  • Suggests potential treatment options of esophageal dysbiosis


Both basic science researchers and gastroenterologists, Primary care physicians dealing with GERD/esophageal disease

Table of Contents

  • 1. Acid: the cornerstone factor in gastroesophageal reflux and related complications
    2. Acid suppression and effects on the microbiome
    3. Esophagogastric microbiome- what is normal?
    4. Esophagogastric microbiome- internal and external influences for variance
    5. Cytokines and immune modulators- Effects on esophageal inflammation
    6. Esophageal dysbiosis and pathogenesis of gastroesophageal Reflux Disease
    7. Esophageal dysbiosis and esophageal neoplasia- from Barrett’s to cancers
    8. Esophageal dysbiosis and Eosinophilic Esophagitis- Bacteria to Blame?
    9. Esophageal dysbiosis and esophageal motility disorders
    10. Esophageal dysbiosis- correcting the paradox – antibiotics, probiotics or prebiotics?

Product details

  • No. of pages: 350
  • Language: English
  • Copyright: © Academic Press 2023
  • Published: February 1, 2023
  • Imprint: Academic Press
  • Paperback ISBN: 9780323950701

About the Editor

David Johnson

Dr. Johnson MD, MACG, FASGE, MACP is Professor of Medicine and Chief of Gastroenterology at Eastern VA School of Medicine. He co-founded the National Medicare Carrier Advisory Committee. He served on the GI Multi-Society CRC Screening Task Force and ACG guidelines committee for CRC screening, and co-authored the national guidelines. He served on the American Board of Internal Medicine (Gastroenterology), Board of Examiners (2012-2017), and was reappointed to the Maintenance of Certification ABIM Board 2020-present. He has been honored with the highest award from the American College of Gastroenterology; the Berk/Fise Award for lifetime achievements, as well as the William D Carey ACG Governors award to lifetime contributions to gastroenterology. He is the physician who worked with Virginia State Senator Emily Couric to put through the historic legislation to mandate colon cancer screening with colonoscopy as the preferred standard. This initiative has set the model for other states which have followed with similar legislation.

Affiliations and Expertise

Professor of Medicine and Chief of Gastroenterology at Eastern VA School of Medicine, Gastrointestinal and Liver Disease Specialists of Tidewater, PLLC/DBA Digestive and Liver Disease Specialists, USA

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