Epigenetics of Cancer Prevention
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Epigenetics of Cancer Prevention

1st Edition - November 27, 2018

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  • Editors: Anupam Bishayee, Deepak Bhatia
  • Hardcover ISBN: 9780128124949
  • eBook ISBN: 9780128125663

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Description

Epigenetics of Cancer Prevention, Volume Ten is the first to look at epigenetics and chemoprevention together. Although there is numerous scientific data available on how epigenetics can lead to cancer and how chemoprevention can be beneficial in the treatment of, or improvement of quality of life, together they will set an advanced understanding for the reader in this upcoming field of chemoprevention influencing epigenetics. This book discusses molecular epigenetic targets of natural products, such as green tea polyphenols, curcumin and resveratrol, and organ specific epigenetic targets related to diverse types of cancer, for example prostate, colorectal, breast, lung and skin cancers. Additionally, it encompasses a discussion on research methods and limitations to study epigenetics and epigenomics of chemopreventive drugs and personalized cancer treatment with phytochemicals. The book is ideal for cancer researchers, health care professionals and all individuals who are interested in cancer prevention research and its clinical applications, especially in natural remedies.

Key Features

  • Lists natural agents, including nutraceuticals, and their effects on normal or tumor genome
  • Addresses various epigenetic systems and mechanisms in the regulation and support of the mammalian genome
  • Discusses how various parts of dietary phytochemicals can influence or modify epigenetic mechanisms in several types of cancer

Readership

Graduate students in cancer and genetics; healthcare professionals; pharmacologists; physicians

Table of Contents

  • Foreword

    I. MOLECULAR EPIGENETIC TARGETS OF NATURAL PRODUCTS

    1. Genetic and Epigenetic Targets of Natural Dietary Compounds as Anticancer Agents
    QIWEN SHI, ANUPAM BISHAYEE, AND DEEPAK BHATIA

    2. Epigenetic Dietary Interventions for Prevention of Cancer
    PRADHAN NIBEDITA, KAR SWAYAMSIDDHA, PARBIN SABNAM, SENGUPTA DIPTA, DEB MOONMOON, DAS LAXMIDHAR, AND PATRA SAMIR KUMAR

    3. Natural Anticancer Agents: Modifying the Epigenome to Prevent and Treat Cancer KRISTINA ANDRIJAUSKAITE, JAY MORRIS, AND MICHAEL J. WARGOVICH

    4. Histone Deacetylase Inhibitors in Cancer Prevention and Therapy
    SHAHRZAD MOVAFAGH AND AMANDA MUNSON

    5. Epigenetic Effects of Curcumin in Cancer Prevention
    MUTHU K. SHANMUGAM, FRANK ARFUSO, JUDY C. SNG, ANUPAM BISHAYEE, ALAN PREM KUMAR, AND GAUTAM SETHI

    6. The Epigenetic Targets of Berry Anthocyanins in Cancer Prevention
    DINA MOUSTAFA ABO EL-ELLA AND ANUPAM BISHAYEE

    7. Isothiocyanates, Epigenetics, and Cancer Prevention
    SILVIA NOVÍO, MARÍA JESÚS NÚÑEZ-IGLESIAS, AND MANUEL FREIRE-GARABAL

    8. Epigenetic Mechanisms of Resveratrol and Its Analogs in Cancer Prevention and Treatment
    AVINASH KUMAR AND ANAIT S. LEVENSON

    9. Epigenetic Mechanisms of Quercetin and Other Flavonoids in Cancer Therapy and Prevention
    GIAN LUIGI RUSSO AND PAOLA UNGARO

    II. ORGAN SPECIFIC EPIGENETIC TARGETS OF NATURAL PRODUCTS

    10. Dietary Phytochemicals, Epigenetics, and Colon Cancer Chemoprevention
    RITIKRAJ ARYA AND SABITA N. SALDANHA

    11. Epigenetic Aspects of Hepatocellular Carcinoma Chemoprevention
    RENATO HEIDOR, ERNESTO VARGAS-MENDEZ, AND FERNANDO SALVADOR MORENO

    12. Epigenetic Control of Pancreatic Carcinogenesis and Its Regulation by Natural Products
    HASEEB ZUBAIR, SHAFQUAT AZIM, MOHAMMAD ASLAM KHAN, GIRIJESH KUMAR PATEL, AAMIR AHMAD, SACHIN PAI, SEEMA SINGH, AND AJAY P. SINGH

    13. Phytochemicals as Epigenetic Modifiers for Cancer Management With Special Reference to Lung Cancer
    TAMILSELVAM RAJAVEL AND KASI PANDIMA DEVI

    14. Epigenetics of Prostate Cancer and Novel Chemopreventive and Therapeutic Approaches DIVYA BHAGIRATH, THAO L. YANG, RAJVIR DAHIYA, SHAHANA MAJID, AND SHARANJOT SAINI

    15. Prevention of Breast Cancer by Food Bioactives in Relation to Cancer Subtypes: Epigenetic Mechanisms
    MICAH G. DONOVAN, ORNELLA I. SELMIN, AND DONATO F. ROMAGNOLO

    16. Epigenomics of Ovarian Cancer and Its Chemoprevention
    OURANIA KOUKOURA, STAVROS SIFAKIS, NIKOLAOS GOUTSIAS, IRONTIANTA GKOREZI-NTAVELA, AND JIANNIS HAJIIOANNOU

    III. MISCELLANEOUS

    17. Dietary and Lifestyle Factors in Epigenetic Regulation of Cancer
    ESWAR SHANKAR, KARISHMA GUPTA, AND SANJAY GUPTA

    18. Epigenetics, Public Health, Lifestyle, and Chemoprevention
    MASSIMO ROMANI AND BARBARA BANELLI

Product details

  • No. of pages: 442
  • Language: English
  • Copyright: © Academic Press 2018
  • Published: November 27, 2018
  • Imprint: Academic Press
  • Hardcover ISBN: 9780128124949
  • eBook ISBN: 9780128125663

About the Editors

Anupam Bishayee

Dr. Bishayee has 25 years combined experience in pharmaceutical education, research, teaching and administration. His primary research interest during last two decades encompasses cancer biology, cancer therapeutics and cancer prevention. His laboratory is involved in investigating mechanism-based chemopreventive and therapeutic effects of various medicinal plants, natural products, dietary and synthetic agents using various pre-clinical models of cancer. The various projects of Dr. Bishayee are funded by the National Institutes of Health as well as private pharmaceutical/biotechnological companies.

Dr. Bishayee has published at least 170 original research papers and authoritative review articles in high-impact, peer-reviewed journals and 15 book chapters, and presented over 25 papers at various national and international scientific meetings. Dr Bishayee is the Editor-in-Chief of two journals and has acted as guest editor of various journals thematic issues. He is also serving as an editorial board member and ad-hoc reviewer of more than 50 reputed journals.

Affiliations and Expertise

Lake Erie College of Osteopathic Medicine, Bradenton, FL, United States

Deepak Bhatia

Dr. Bhatia has 10 years of experience in pharmaceutical education, research and training medical, pharmacy and graduate students. His essential research interest is in mechanistic studies of solid tumors and use of plant-based therapeutics for malignancy aversion. His research involves utilizing both in vitro and in vivo techniques to study gene regulation and epigenetic regulation of key genes and proteins involved in growth suppression, proliferation and inflammation. Dr. Bhatia has extensively published original research papers and review articles in high-impact, peer-reviewed journals and contributed to numerous book chapters. He has presented his research both at national and international scientific meetings. Dr. Bhatia is an Editor of two journals and serves as an editorial board member and ad-hoc reviewer of many reputed journals.

Affiliations and Expertise

Department of Pharmacogenomics, Bernard J Dunn School of Pharmacy, Shenandoah University, Fairfax, VA, United States

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  • HeikoSchuebel Sat Mar 30 2019

    up-to-date information about nutritional ways to prevent cancer

    Great book with up-to-date information about the epigenetic possibilities for cancer prevention with natural compounds. Worth the price!