
Epigenetics in Cardiovascular Disease
Description
Key Features
- Offers a thorough overview of role of epigenetics mechanisms in cardiovascular disease
- Includes guidance to improve research plans, experimental protocols design, quality and reproducibility of results in new epigenetics research
- Explores biomarkers and drug targets of therapeutic potential to advance personalized healthcare
- Features chapter contributions from a wide range of international researchers in the field
Readership
Table of Contents
Preface
SECTION I INTRODUCTORY INFORMATION
CHAPTER 1 The ever-growing burden of cardiovascular disease
CHAPTER 2 Epigenetics concepts: An overview
CHAPTER 3 From classical signaling pathways to the nucleusSECTION II EPIGENETICS MECHANISMS IN CARDIOVASCULAR DISEASE
CHAPTER 4 DNA methylation in heart failure
CHAPTER 5 Histone modifications in cardiovascular disease initiation and progression
CHAPTER 6 RNA modifications in cardiovascular disease—An experimental and computational perspective
CHAPTER 7 Regulatory RNAs in cardiovascular disease
CHAPTER 8 Regulation of splicing in cardiovascular disease
CHAPTER 9 Cardiac transcriptomic remodeling in metabolic syndrome
CHAPTER 10 Sex differences in epigenetics mechanisms of cardiovascular disease
CHAPTER 11 Epigenetics in cardiac development and human induced pluripotent stem cellsSECTION III BIOMARKER VALUE
CHAPTER 12 Peripheral blood DNA and RNA biomarkers of cardiovascular disease in clinical practice
CHAPTER 13 Epigenetics and physical exercise
CHAPTER 14 Long noncoding RNAs and circular RNAs as heart failure biomarkers
CHAPTER 15 Artificial intelligence in clinical decision-making for diagnosis of cardiovascular disease using epigenetics mechanismsSECTION IV THERAPEUTIC POTENTIAL
CHAPTER 16 Therapeutic strategies for modulating epigenetic mechanisms in cardiovascular diseaseSECTION V METHODOLOGICAL ISSUES
CHAPTER 17 Single-cell RNA sequencing in cardiovascular science
CHAPTER 18 Good laboratory and experimental practices for microRNA analysis in cardiovascular research
CHAPTER 19 Analytical challenges in microRNA biomarker development: Best practices for analyzing microRNAs in cell-free biofluids
CHAPTER 20 Concept of biological reference materials for RNA analysis in cardiovascular disease
CHAPTER 21 Unbiased bioinformatics analysis of microRNA transcriptomics datasets and network theoretic target prediction
Conclusions and Prespectives
Product details
- No. of pages: 498
- Language: English
- Copyright: © Academic Press 2021
- Published: March 6, 2021
- Imprint: Academic Press
- Paperback ISBN: 9780128222584
- eBook ISBN: 9780128222591
About the Editors
Yvan Devaux
Affiliations and Expertise
Emma Robinson
Affiliations and Expertise
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