Epidemiology of Leukaemia and Lymphoma

Epidemiology of Leukaemia and Lymphoma contains the proceedings of the Leukaemia Research Fund International Workshop held in Oxford, UK, on September 25-27, 1984. Contributors explore the epidemiology of leukemia and lymphoma based on the results of a pilot study that investigated whether careful subdivision of acute lymphoblastic leukemia (ALL) using a standardized panel of monoclonal antibodies would reveal interesting associations between subtypes and particular geographic regions or ethnic groups within regions. This book is comprised of 31 chapters divided into four sections and begins with a discussion on epidemiological approaches to hematological malignancy, paying particular attention to international data collection and interpretation; clusters and associations in cancer epidemiology; and childhood leukemia in Great Britain and the Netherlands. The next section explores the causes of human leukemia and lymphoma as well as the epidemiology of leukemia and lymphoma subtypes in various regions of the world such as Africa, Asia, United States, and Mediterranean region. The final section focuses on practical problems in standardized immunophenotyping of leukemias and lymphomas; immuno-alkaline phosphatase labeling of hematological samples; and detection of surface membrane antigens by a rosette assay using antibody coupled red cells. This monograph will be of value to clinicians and medical practitioners interested in the epidemiology of leukemia and lymphoma.

Preface Photograph and List of Participants Part 1. Epidemiological Approaches to Hematological Malignancy International Data Collection and Interpretation: A Review Searching for Clusters and Associations in Cancer Epidemiology Descriptive Epidemiology of Childhood Leukemia and Lymphoma in Great Britain Recent Epidemiological Studies of Leukemia in the United Kingdom Epidemiological and Immunological Characteristics of Childhood Leukemia in the Netherlands: Population-based Data from a Nationwide Co-operative Group of Pediatricians Part 2. Identifying Causes of Leukemia/Lymphoma Viruses as Risk Factors or Causes of Human Leukemias and Lymphomas Epidemiology of Human Retroviruses The value of Sub-typing in Studies of Irradiation and Human Leukemia Inherited Factors in Leukemia and Lymphoma Animal Models: Lessons from Feline and Bovine Leukemia Virus Infections Part 3. The Geography of Leukemia and Lymphoma Subtypes Collaborative Group Study of the Epidemiology of Acute Lymphoblastic Leukemia Subtypes: Background and First Report Africa: The Epidemiology of Lymphomas and Leukemias in Africa — An Overview Influence of Life-style on the Pattern of Leukemia and Lymphoma Subtypes among Nigerians Leukemia and Lymphoma in Kenya Preliminary Communication on Leukemia Cell Markers in Kenya Immunophenotypic Classification of Lymphoblastic Leukemia and Lymphocytic Lymphoma — An Experience in the South-western Area of the Cape Province of South Africa Acute Childhood Leukemia in Johannesburg Mediterranean Region: Observations on the Epidemiology and Subtypes of Lymphatic Malignancies in Israel Childhood T-Cell Acute Lymphoblastic Leukemia in the Campania Region of Italy Epidemiology and Immunological Phenotype of Childhood All in Greece Asia: Epidemiology of Leukemias in the People's Republic of China Epidemiologic and Immunologic Characteri