Enzyme Catalysis and Control - 1st Edition - ISBN: 9780121528249, 9781483217239

Enzyme Catalysis and Control, Volume 24

1st Edition

Editors: Marlene Deluca Henry Lardy Richard L. Cross
eBook ISBN: 9781483217239
Imprint: Academic Press
Published Date: 13th August 1984
Page Count: 534
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Table of Contents


Contributors


Introduction


Acknowledgment


Paul Boyer


Conference Photographs


1. NMR Studies of Phosphoryl Transfer Reactions


2. Role of Water on the Free Energy of Hydrolysis of Pyrophosphate


3. Control of Oxygen Delivery from the Erythrocyte by Modification of Pyruvate Kinase


4. Hormonal Actions of Vitamin D


5. Interaction of Galactosyltransferase with α-Lactalbumin and Substrates


6. Regulation of Lipid Metabolism by a Lipid-Carrying Protein


7. Selenium-Glutathione Peroxidase: Properties and Synthesis


8. Regulation of Metabolism in Penicillium charlesii by Organic Acids: Role of L-Tartaric Acid


9. Kinetic Analysis of the Specificity of Multisubstrate Carnitine Palmitoyltransferase


10. GABA and Taurine Enzymes in Mammalian Brain


11. Biochemistry and Regulation of Signal Transduction by Neuronal Acetylcholine Receptors


12. Enzymes of Glutamate and Glutamine Biosynthesis in Bacillus licheniformis


13. Glutamine Synthetase: The Major Mn(II) Enzyme in Mammalian Brain


14. Regulation of Gluconeogenesis at Phosphoenolpyruvate Carboxykinase


15. Involvement of Guanidino Groups in Anion-Binding Sites and in Enzyme-Catalyzed Covalent Modification Reactions


16. Use of Coimmobilized Multienzyme Systems as Models for in Vivo Processes


17. Mechanism and Regulation of Bovine Liver Fructose-1,6-bisphosphatase


18. Equilibrium Kinetic Studies of Enzyme Mechanism and Control


19. Kinetics of Tryptophanase Inactivation/Activation by Sudden Removal/Addition of Potassium Ions with the Aid of a Crown Ether or Cryptand


20. Mechanism and Regulation of Protein Turnover: Effect of the α-Mannosidase Inhibitor, Swainsonine, on Glycoprotein Degradation


21. Inhibition of Protein Synthesis Initiation Factors by Naturally Occurring Sulfhydryl Reactive Reagents


22. Struc


Description

Current Topics in Cellular Regulation: Volume 24, Enzyme Catalysis and Control is a compendium of papers that discusses phosphoryl transfer reactions, the role of water on the free energy of hydrolysis of pyrophosphate, and the hormonal actions of vitamin D. Other papers describe the regulation lipid metabolism by a lipid-carrying protein, the GABA, and taurine enzymes in mammalian brain. One paper examines the role of vitamin D in the metabolism of cells, as well as in the whole animal. Upon absorption in the body, the vitamin undergoes various metabolic transformations before interacting with specific receptors, and then inducting the genome in the target tissues to generate biological and hormonal responses. Another paper notes the possibility of a genetic defect in cancer cells that results in the abnormal accumulation of sterol carrier protein (SCP) and cholesterol in vivo; and also in the inability to maintain levels of SCP or cholesterol in vitro. One paper shows that tartrate, or other organic acids, secreted into the medium by the penicillia keeps the pH in an optimal range for acid protease degradation of proteins and glycoproteins. This mechanism helps the fungus to survive in a nutrient environment (which is unbalanced with respect to an optimum C/N ratio and at a pH unfavorable to many bacteria and other life forms). Another paper proposes a model for the modulation of ATP synthetase activities and medium exchange reactions by energy input, substrate concentration, or others that affect the microenvironment of the enzyme under certain conditions. The compendium will prove beneficial to molecular biologists, general biologists, microbiologists, and biochemists.


Details

No. of pages:
534
Language:
English
Copyright:
© Academic Press 1984
Published:
Imprint:
Academic Press
eBook ISBN:
9781483217239

Ratings and Reviews


About the Editors

Marlene Deluca Editor

Henry Lardy Editor

Richard L. Cross Editor