Endocrine Gland Development and Disease - 1st Edition - ISBN: 9780124160217, 9780123914545

Endocrine Gland Development and Disease, Volume 106

1st Edition

Serial Volume Editors: Paul Thomas
eBook ISBN: 9780123914545
Hardcover ISBN: 9780124160217
Imprint: Academic Press
Published Date: 17th December 2013
Page Count: 344
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Table of Contents

Series Page

Contributors

Preface

Chapter One. Pituitary Gland Development and Disease: From Stem Cell to Hormone Production

Abstract

1 Introduction

2 Regulating the Pituitary Organizer and the Growth and Shape of Rathke’s Pouch

3 Activities of Signaling Pathways Intrinsic to Rathke’s Pouch

4 The Role of Signature Transcription Factors in Cell Specification

5 Early-Acting Transcription Factors

6 Emerging Roles for Additional Transcription Factor Families: The Forkheads

7 Pituitary Progenitors: Stem Cells and the Niche

8 Cell Cycle Regulation

9 Vascularization and the Hypophyseal Portal System

10 Conclusion

References

Chapter Two. Development of the Medial Hypothalamus: Forming a Functional Hypothalamic-Neurohypophyseal Interface

Abstract

Abbreviations

1 Introduction

2 Architecture of the Adult Medial Hypothalamus

3 Establishing the Medial Hypothalamus

4 Signaling Ligands in Induction and Regionalization

5 Neuronal Differentiation in the Medial Hypothalamus

6 Establishment of Interfaces

7 Concluding Remarks

Acknowledgments

References

Chapter Three. Mammalian Sex Determination and Gonad Development

Abstract

1 Introduction

2 Development of the Bipotential Genital Ridge

3 Primordial Germ Cells

4 Let Us Get It on: Activation of the Testis Differentiation Pathway

5 Staying Turned on: Activation and Maintenance of Sox9

6 Ovary Differentiation

7 Molecular Genetics of Ovarian Development

8 Mutual Antagonism

9 Conclusions and Future Perspectives

References

Chapter Four. Mechanisms of Thyroid Development and Dysgenesis: An Analysis Based on Developmental Stages and Concurrent Embryonic Anatomy

Abstract

1 Introduction

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Description

This new volume of Current Topics in Developmental Biology covers endocrine gland development and disease, and with contributions from an international board of authors. The chapters provide a comprehensive set of reviews covering such topics as sex determination & gonadogenesis, hypothalamus, paraythyroid and placenta.

Key Features

  • Covers the area of endocrine gland development and disease
  • International board of authors
  • Provides a comprehensive set of reviews covering such topics as sex determination & gonadogenesis and the adrenal, thyroid and pineal glands.

Readership

Researchers in cell, developmental, and molecular biology; genetics


Details

No. of pages:
344
Language:
English
Copyright:
© Academic Press 2013
Published:
Imprint:
Academic Press
eBook ISBN:
9780123914545
Hardcover ISBN:
9780124160217

Ratings and Reviews


About the Serial Volume Editors

Paul Thomas Serial Volume Editor

Affiliations and Expertise

School of Biomedical Science, University of Adelaide, Australia