Endocrine Gland Development and Disease

Endocrine Gland Development and Disease

1st Edition - November 27, 2013

Write a review

  • Editor: Paul Thomas
  • eBook ISBN: 9780123914545
  • Hardcover ISBN: 9780124160217

Purchase options

Purchase options
DRM-free (EPub, PDF, Mobi)
Available
Sales tax will be calculated at check-out

Institutional Subscription

Free Global Shipping
No minimum order

Description

This new volume of Current Topics in Developmental Biology covers endocrine gland development and disease, and with contributions from an international board of authors. The chapters provide a comprehensive set of reviews covering such topics as sex determination & gonadogenesis, hypothalamus, paraythyroid and placenta.

Key Features

  • Covers the area of endocrine gland development and disease
  • International board of authors
  • Provides a comprehensive set of reviews covering such topics as sex determination & gonadogenesis and the adrenal, thyroid and pineal glands.

Readership

Researchers in cell, developmental, and molecular biology; genetics

Table of Contents

  • Series Page

    Contributors

    Preface

    Chapter One. Pituitary Gland Development and Disease: From Stem Cell to Hormone Production

    Abstract

    1 Introduction

    2 Regulating the Pituitary Organizer and the Growth and Shape of Rathke’s Pouch

    3 Activities of Signaling Pathways Intrinsic to Rathke’s Pouch

    4 The Role of Signature Transcription Factors in Cell Specification

    5 Early-Acting Transcription Factors

    6 Emerging Roles for Additional Transcription Factor Families: The Forkheads

    7 Pituitary Progenitors: Stem Cells and the Niche

    8 Cell Cycle Regulation

    9 Vascularization and the Hypophyseal Portal System

    10 Conclusion

    References

    Chapter Two. Development of the Medial Hypothalamus: Forming a Functional Hypothalamic-Neurohypophyseal Interface

    Abstract

    Abbreviations

    1 Introduction

    2 Architecture of the Adult Medial Hypothalamus

    3 Establishing the Medial Hypothalamus

    4 Signaling Ligands in Induction and Regionalization

    5 Neuronal Differentiation in the Medial Hypothalamus

    6 Establishment of Interfaces

    7 Concluding Remarks

    Acknowledgments

    References

    Chapter Three. Mammalian Sex Determination and Gonad Development

    Abstract

    1 Introduction

    2 Development of the Bipotential Genital Ridge

    3 Primordial Germ Cells

    4 Let Us Get It on: Activation of the Testis Differentiation Pathway

    5 Staying Turned on: Activation and Maintenance of Sox9

    6 Ovary Differentiation

    7 Molecular Genetics of Ovarian Development

    8 Mutual Antagonism

    9 Conclusions and Future Perspectives

    References

    Chapter Four. Mechanisms of Thyroid Development and Dysgenesis: An Analysis Based on Developmental Stages and Concurrent Embryonic Anatomy

    Abstract

    1 Introduction

    2 Anatomy and Phylogenic Aspects of Thyroid Development

    3 Thyroid Organogenesis and Spectrum of Developmental Defects in Human

    4 Thyroid Specification and Determination: Agenesis Versus Athyreosis

    5 Embryonic Thyroid Growth: Hypoplasia and Hemiagenesis

    6 Defective Thyroid Migration: Ectopic Gland

    7 Folliculogenesis and Thyroid Differentiation

    8 Embryonic Origin of Thyroid C Cells: An Unresolved Issue

    9 Concluding Remarks

    Acknowledgments

    References

    Chapter Five. The Pineal Gland from Development to Function

    Abstract

    1 Function of the Pineal Gland

    2 Cellular Composition of the Pineal Gland

    3 Organogenesis of the Pineal Gland, Production of Accessory Organs

    4 Development of the Pineal Gland

    5 Physiological Roles of Melatonin

    6 Pathological Dysregulation of Melatonin Synthesis/Signaling

    7 Conclusion

    Acknowledgments

    References

    Chapter Six. From Pancreas Morphogenesis to β-Cell Regeneration

    Abstract

    1 Anatomy of the Pancreas

    2 Diabetes

    3 Pancreatic Morphogenesis

    4 The Endocrine Differentiation Program

    5 Regenerative Medicine

    Acknowledgments

    References

    Chapter Seven. Adrenocortical Development, Maintenance, and Disease

    Abstract

    1 Introduction

    2 The Adrenal Gland: Structure and Function

    3 Adrenal Development

    4 Theories of Growth and Zonation

    5 Factors Involved in Adrenal Development

    6 Signaling Pathways Involved in Adrenal Development

    7 Models of Development

    8 Control of Postnatal Growth, Zonation, and Remodeling

    9 Diseases of the Adrenal Cortex

    10 Summary

    References

    Index

Product details

  • No. of pages: 344
  • Language: English
  • Copyright: © Academic Press 2013
  • Published: November 27, 2013
  • Imprint: Academic Press
  • eBook ISBN: 9780123914545
  • Hardcover ISBN: 9780124160217

About the Serial Volume Editor

Paul Thomas

Affiliations and Expertise

School of Biomedical Science, University of Adelaide, Australia

Ratings and Reviews

Write a review

There are currently no reviews for "Endocrine Gland Development and Disease"