Economic Evaluation in Genomic Medicine - 1st Edition - ISBN: 9780128014974, 9780128016114

Economic Evaluation in Genomic Medicine

1st Edition

Authors: Vasilios Fragoulakis Christina Mitropoulou Marc Williams George Patrinos
eBook ISBN: 9780128016114
Paperback ISBN: 9780128014974
Imprint: Academic Press
Published Date: 25th March 2015
Page Count: 174
Tax/VAT will be calculated at check-out Price includes VAT (GST)
30% off
30% off
30% off
30% off
30% off
20% off
20% off
30% off
30% off
30% off
30% off
30% off
20% off
20% off
30% off
30% off
30% off
30% off
30% off
20% off
20% off
64.95
45.47
45.47
45.47
45.47
45.47
51.96
51.96
89.95
62.97
62.97
62.97
62.97
62.97
71.96
71.96
54.99
38.49
38.49
38.49
38.49
38.49
43.99
43.99
Unavailable
Price includes VAT (GST)
× DRM-Free

Easy - Download and start reading immediately. There’s no activation process to access eBooks; all eBooks are fully searchable, and enabled for copying, pasting, and printing.

Flexible - Read on multiple operating systems and devices. Easily read eBooks on smart phones, computers, or any eBook readers, including Kindle.

Open - Buy once, receive and download all available eBook formats, including PDF, EPUB, and Mobi (for Kindle).

Institutional Access

Secure Checkout

Personal information is secured with SSL technology.

Free Shipping

Free global shipping
No minimum order.

Description

Economic Evaluation in Genomic Medicine introduces health economics and economic evaluation to genomic clinicians and researchers, while also introducing the topic to health economists.

Each chapter includes an executive summary, questions, and case studies, along with supplementary online materials, including process guides, maps, flow charts, diagrams, and economic evaluation spreadsheets to enhance the learning process.

The text can easily be used as course material for related graduate and undergraduate courses, providing a succinct overview of the existing, state-of-the-art application of economic evaluation to genomic healthcare and precision medicine.

Key Features

  • Interrelates economic evaluation and genomic medicine
  • Instructs healthcare professionals and bioscientists about economic evaluation in genomic medicine
  • Teaches health economists about application of economic evaluation in genomic medicine
  • Introduces health economics and economic evaluation to clinicians and researchers involved in genomics
  • Includes process guides, maps, flow charts and diagrams

Readership

Bioscientists, geneticists, biotech industry professionals, undergraduate and graduate students in health economics and health sciences (namely medicine, pharmacy, and genetics), clinicians and health managers, public health officers, health policy makers, governmental organizations, health care professionals, hospital managers, healthcare policy makers

Table of Contents

  • Preface
  • Chapter 1. Economic Evaluation in Health Care: Evidence-Based Medicine and Evidence-Based Health Economics
    • The Scope of Economic Evaluation of Health Services: The Science of Economics
    • Evidence-Based Medicine and Evidence-Based Health Economics
    • The Necessity of Drafting Economic Evaluations
    • References
  • Chapter 2. Genomic Medicine Today: An Introduction for Health Economists
    • Introduction
    • Pharmacogenomics and Genomic Medicine
    • Applications of Pharmacogenomics
    • Facing the Current Challenges of Genomic Medicine
    • Education of Health Professionals
    • Demonstration of Clinical Utility
    • Health Care Costs
    • Insurance and Privacy Issues
    • Conclusions and Future Perspectives
    • References
  • Chapter 3. Economic Evaluation and Genomic Medicine: What Can They Learn from Each Other?
    • Introduction
    • Genomics in Health Economics
    • Triangulating Genomics with Health Technology Assessment and Health Economics
    • Economic Evaluation in the Postgenomic Era
    • References
  • Chapter 4. Introduction to the Technical Issues of Economic Evaluation
    • Introduction
    • Unique Aspects and Differentiation of CEA from Alternative Approaches
    • An Appropriate Measure for CEA
    • CEA Decision Criteria
    • The Concept of Extended Dominance
    • Selection of Alternative Options During Economic Evaluation
    • Valuing the Quality of Life–Cost–Utility Analysis
    • A Conceptual Approach to QALY
    • Assessing the Quality of an Economic Analysis
    • Conclusions
    • References
  • Chapter 5. Advanced Methodological Aspects in the Economic Evaluation
    • Introduction
    • Model Types
    • The Size of the ICER or the λ
    • Estimates of Effectiveness
    • Study Perspective and Cost Determination
    • The Discount Rate
    • Sensitivity Analysis
    • The Value of Information and Bayesian Analysis
    • Conclusions
    • References
  • Chapter 6. Economic Evaluation in the Genomic Era: Some Examples from the Field
    • Introduction
    • Using Pharmacogenomics to Prevent Adverse Events
    • Balancing Adverse Events and Efficacy
    • The Disease Makes a Difference
    • Perspectives on Perspective
    • Defining Performance Characteristics
    • Cost-Effectiveness Analysis in Genomic Medicine and the Developing World
    • Conclusions
    • References
  • Chapter 7. Special Requirements for Economic Evaluation and Health Technology Assessment in Genomic Medicine
    • Introduction
    • Analysis Costs
    • Analysis Method
    • Outcome of Analysis
    • Analysis Effectiveness
    • Conclusions
    • References
  • Chapter 8. A New Methodological Approach for Cost-Effectiveness Analysis in Genomic Medicine
    • Introduction
    • New Methodological Framework of the Decision-Making Process in Genomic Medicine
    • Relaxation of Fixed λ
    • A Simple Indicative Example
    • An Application of the New Model in Genomic Medicine
    • Implications
    • Conclusions
    • References
  • Chapter 9. Conclusions and Future Perspectives
    • Introduction
    • Conclusions
    • References
  • Index

Details

No. of pages:
174
Language:
English
Copyright:
© Academic Press 2015
Published:
Imprint:
Academic Press
eBook ISBN:
9780128016114
Paperback ISBN:
9780128014974

About the Author

Vasilios Fragoulakis

Affiliations and Expertise

University of Patras School of Health Sciences, Department of Pharmacy, Patras, Greece; National School of Public Health, Athens, Greece

Christina Mitropoulou

Affiliations and Expertise

Erasmus University Medical Center, Department of Clinical Chemistry, Rotterdam, The Netherlands

Marc Williams

Affiliations and Expertise

Geisinger Health System, Danville, Pennsylvanian, USA

George Patrinos

Dr. George Patrinos is an Associate Professor at the University of Patras School of Health Sciences (Department of Pharmacy) in Patras, Greece with Adjunct positions in Rotterdam, the Netherlands and Al-Ain, United Arab Emirates. His research interests span the fields of molecular diagnostics, high-throughput mutation screening, the development of online mutation diagnostic tools, and the implementation of genomics in healthcare, particularly for health systems in developing countries. George Patrinos has published more than 170 scientific papers in peer reviewed journals on topics related to genetics, genomic medicine, pharmacogenomics, molecular diagnostics, and social and economic evaluation for genomic medicine. Dr. Patrinos is also the co-author of Economic Evaluation in Genomic Medicine (2015) and co-Editor of Molecular Diagnostics, Second Edition (2009), both published by Elsevier, and serves as Communicating Editor for the journal Human Mutation. Additionally, he is co-organizer of the international meeting series “Golden Helix Symposia” and “Golden Helix Pharmacogenomics Days”.

Affiliations and Expertise

Associate Professor, Pharmacogenomics and Pharmaceutical Biotechnology, University of Patras, Greece

Reviews

"...provides a useful introduction to health economics for non-specialists interested in how it can be applied to genomics, and the relevance of this on policy, reimbursement, and availability of diagnostics and related therapies." --European Journal of Human Genetics, Economic Evaluation in Genomic Medicine