Drug-Induced Liver Injury - 1st Edition - ISBN: 9780128167595, 9780128173176

Drug-Induced Liver Injury, Volume 85

1st Edition

Serial Volume Editors: Anup Ramachandran Hartmut Jaeschke
Hardcover ISBN: 9780128167595
eBook ISBN: 9780128173176
Imprint: Academic Press
Published Date: 13th July 2019
Page Count: 288
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Table of Contents

1. Primary hepatocytes and their cultures for the testing of drug-induced liver injury
Vânia Vilas-Boas, Axelle Cooreman, Eva Gijbels, Raf Van Campenhout, Emma Gustafson, Steven Ballet, Pieter Annaert, Bruno Cogliati and Mathieu Vinken
2. Cell death in drug-induced liver injury
Andrea Iorga and Lily Dara
3. Drug-induced liver injury in obesity and nonalcoholic fatty liver disease
Julien Allard, Dounia Le Guillou, Karima Begriche and Bernard Fromenty
4. Role and mechanisms of autophagy in alcohol-induced liver injury
Xiaojuan Chao and Wen-Xing Ding
5. Mechanisms of idiosyncratic drug-induced liver injury
Jack Uetrecht
6. Idiosyncratic drug-induced liver injury in patients: detection, severity assessment, and regulatory implications
Paul B. Watkins
7. Acetaminophen hepatotoxicity: A mitochondrial perspective
Anup Ramachandran and Hartmut Jaeschke
8. Biomarkers of drug-induced liver injury
Mitchell R. McGill and Hartmut Jaeschke
9. Mechanisms and biomarkers of liver regeneration after drug-induced liver injury
Melissa M. Clemens, Mitchell R. McGill and Udayan Apte
10. Evaluation and treatment of acetaminophen toxicity
Erik S. Fisher and Steven C. Curry


Description

Drug-Induced Liver Injury, Volume 85, the newest volume in the Advances in Pharmacology series, presents a variety of chapters from the best authors in the field. Chapters in this new release include Cell death mechanisms in DILI, Mitochondria in DILI, Primary hepatocytes and their cultures for the testing of drug-induced liver injury, MetaHeps an alternate approach to identify IDILI, Autophagy and DILI, Biomarkers and DILI, Regeneration and DILI, Drug-induced liver injury in obesity and nonalcoholic fatty liver disease, Mechanisms of Idiosyncratic Drug-Induced Liver Injury, the Evaluation and Treatment of Acetaminophen Toxicity, and much more.

Key Features

  • Includes the authority and expertise of leading contributors in pharmacology
  • Presents the latest release in the Advances in Pharmacology series

Readership

Investigators in neuroscience, pharmacology, neurology, psychiatry, medicine


Details

No. of pages:
288
Language:
English
Copyright:
© Academic Press 2019
Published:
13th July 2019
Imprint:
Academic Press
Hardcover ISBN:
9780128167595
eBook ISBN:
9780128173176

Ratings and Reviews


About the Serial Volume Editors

Anup Ramachandran Serial Volume Editor

Anup Ramachandran is at University of Kansas Medical Center, KS, USA

Affiliations and Expertise

University of Kansas Medical Center, KS, USA

Hartmut Jaeschke Serial Volume Editor

Hartmut Jaeschke is at University of Kansas Medical Center, KS, USA

Affiliations and Expertise

University of Kansas Medical Center, KS, USA