Down Syndrome: From Understanding the Neurobiology to Therapy - 1st Edition - ISBN: 9780444542991, 9780444543004

Down Syndrome: From Understanding the Neurobiology to Therapy, Volume 197

1st Edition

Serial Volume Editors: Mara Dierssen Rafael de la Torre Fornell
Hardcover ISBN: 9780444542991
eBook ISBN: 9780444543004
Imprint: Elsevier
Published Date: 10th May 2012
Page Count: 272
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Table of Contents

  1. Therapeutic approaches in the improvement of cognitive performance in Down syndrome: past, present and future
  2. Rafael de la Torre and Mara Dierssen

  3. Genomic determinants in the phenotypic variability of Down syndrome
  4. Audrey Letourneau and Stylianos E. Antonarakis

  5. Intellectual disabilities, neuronal post-transcriptional RNA-metabolism and RNA-binding proteins: three actors for a complex scenario
  6. Barbara Bardoni, Sabiha Abekhoukh, Samantha Zongaro and Mireille Melko

  7. Aberrant epigenetic landscape in mental retardation
  8. Sanchez-Mut JV, Huertas D. and Esteller M.

  9. Pathways to cognitive deficits in Down syndrome
  10. Xiaolu Sturgeon, Thanh Le, Md. Mahiuddin Ahmed and Katheleen J. Gardiner

  11. Neurological Phenotypes for Down Syndrome across the Lifespan
  12. Ira T. Lott, MD

  13. Human and mouse model cognitive phenotypes in Down syndrome: Implications for assessment
  14. Jamie O. Edgin, Gina M. Mason, Goffredina Spanò, Andrea Fernández and Lynn Nadel

  15. Perturbation of dendritic protrusions in intellectual disability
  16. Josien Levenga and Rob Willemsen

  17. The in vivo Down syndrome genomic library in mouse
  18. Yann Herault, Arnaud Duchon, Emilie Velot, Damien Maréchal and Véronique Brault

  19. Discoveries in Down Syndrome: Moving Basic Science to Clinical Care
  20. A.M. Kleschevnikov, P.V. Belichenko, A. Salehi and C. Wu

  21. A Sonic hedgehog (Shh) response deficit in trisomic cells may be a common denominator for multiple features of Down syndrome
  22. Duane G. Currier, Renita C. Polk and Roger H. Reeves

  23. Gene therapy for Down syndrome

    Cristina Fillat and Xavier Altafaj

Description

  1. Therapeutic approaches in the improvement of cognitive performance in Down syndrome: past, present and future
  2. Rafael de la Torre and Mara Dierssen

  3. Genomic determinants in the phenotypic variability of Down syndrome
  4. Audrey Letourneau and Stylianos E. Antonarakis

  5. Intellectual disabilities, neuronal post-transcriptional RNA-metabolism and RNA-binding proteins: three actors for a complex scenario
  6. Barbara Bardoni, Sabiha Abekhoukh, Samantha Zongaro and Mireille Melko

  7. Aberrant epigenetic landscape in mental retardation
  8. Sanchez-Mut JV, Huertas D. and Esteller M.

  9. Pathways to cognitive deficits in Down syndrome
  10. Xiaolu Sturgeon, Thanh Le, Md. Mahiuddin Ahmed and Katheleen J. Gardiner

  11. Neurological Phenotypes for Down Syndrome across the Lifespan
  12. Ira T. Lott, MD

  13. Human and mouse model cognitive phenotypes in Down syndrome: Implications for assessment
  14. Jamie O. Edgin, Gina M. Mason, Goffredina Spanò, Andrea Fernández and Lynn Nadel

  15. Perturbation of dendritic protrusions in intellectual disability
  16. Josien Levenga and Rob Willemsen

  17. The in vivo Down syndrome genomic library in mouse
  18. Yann Herault, Arnaud Duchon, Emilie Velot, Damien Maréchal and Véronique Brault

  19. Discoveries in Down Syndrome: Moving Basic Science to Clinical Care
  20. A.M. Kleschevnikov, P.V. Belichenko, A. Salehi and C. Wu

  21. A Sonic hedgehog (Shh) response deficit in trisomic cells may be a common denominator for multiple features of Down syndrome
  22. Duane G. Currier, Renita C. Polk and Roger H. Reeves

  23. Gene therapy for Down syndrome

    Cristina Fillat and Xavier Altafaj

Key Features

  • Leading authors review the state-of-the-art in their field of investigation and provide their views and perspectives for future research
  • Chapters are extensively referenced to provide readers with a comprehensive list of resources on the topics covered
  • All chapters include comprehensive background information and are written in a clear form that is also accessible to the non-specialist

Readership

Neuroscientists, psychologists, neurologists


Details

No. of pages:
272
Language:
English
Copyright:
© Elsevier 2012
Published:
Imprint:
Elsevier
eBook ISBN:
9780444543004
Hardcover ISBN:
9780444542991

About the Serial Volume Editors

Mara Dierssen Serial Volume Editor

Rafael de la Torre Fornell Serial Volume Editor