Current Topics in Cellular Regulation - 1st Edition - ISBN: 9780121528133, 9781483217123

Current Topics in Cellular Regulation, Volume 13

1st Edition

Editors: Bernard L. Horecker Earl R. Stadtman
eBook ISBN: 9781483217123
Imprint: Academic Press
Published Date: 28th June 1978
Page Count: 334
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Table of Contents


Contents


List of Contributors


Posttranslational NH2-Terminal Aminoacylation


I. Introduction


II. Enzymology of Aminoacyl-tRNA Protein Transferases


III. Analysis of Acceptor Proteins


IV. Analysis of Mutant Phenotypes


V. Discussion


Note Added in Proof


References


The Regulation of Liver Pyruvate Kinase by Phosphorylation-Dephosphorylation


I. Introduction


II. Purification and Some Properties of Liver Pyruvate Kinase


III. Phosphorylation of Liver Pyruvate Kinase in Vitro and Its Effect on the Kinetic Properties of the Enzyme


IV. Phosphorylated Site of Pig Liver Pyruvate Kinase. Subtilisin-Catalyzed Modification


V. The Protein Kinase Reaction with Pyruvate Kinase as Substrate


VI. Phosphorylation of Peptides with Structures Related to the Phosphorylatable Site of Pyruvate Kinase


VII. Dephosphorylation of Pyruvate Kinase with Phosphoprotein Phosphatase


VIII. Rapid Hormonal Regulation of Pyruvate Kinase in Vivo


IX. Conclusions


References


Interconvertible Enzyme Cascades in Metabolic Regulation


I. Introduction


II. Monocyclic Cascade Systems


III. Bicyclic Cascade Systems


IV. Multicyclic Cascade Systems


V. Discussion


References


Metabolic Effects of Fructose in the Liver


I. Introduction


II. Metabolism of Fructose in the Liver


III. Influence of Fructose on the Metabolism of Glycogen


IV. Effect of Fructose on the Catabolism of Purine Nucleotides


V. Influence of Fructose on Lipid Metabolism


VI. Effect of Fructose on Alcohol Metabolism


VII. Concluding Remarks


References


Lactose Operator-Repressor Inte


Description

Current Topics in Cellular Regulation, Volume 13 emphasizes the basic mechanisms involved in the regulation of diverse cellular activities.

This book discusses the enzymology of aminoacyl-tRNA protein transferases, analysis of mutant phenotypes, and protein kinase reaction with pyruvate kinase as substrate. The rapid hormonal regulation of pyruvate kinase in vivo, interconvertible enzyme cascades in metabolic regulation, monocyclic cascade systems, and metabolism of fructose in the liver are also elaborated. This publication likewise covers the influence of fructose on lipid metabolism, lactose operator-repressor interaction, and regulation of nitrogenase synthesis. Other topics include the involvement of isozymes in metabolic regulation and molecular approach to the complement system.

This volume is a good reference for biologists and researchers conducting work on the advances in the general area of cellular regulation.


Details

No. of pages:
334
Language:
English
Copyright:
© Academic Press 1978
Published:
Imprint:
Academic Press
eBook ISBN:
9781483217123

Ratings and Reviews


About the Editors

Bernard L. Horecker Editor

Earl R. Stadtman Editor