Current Topics in Bioenergetics

Current Topics in Bioenergetics

Volume 5

1st Edition - January 1, 1973

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  • Editors: D. Rao Sanadi, Lester Packer
  • eBook ISBN: 9781483216898

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Current Topics in Bioenergetics, Volume 5 provides information pertinent to the molecular properties of purified enzymes and defined reactions. This book presents the development in the research on oxidative phosphorylation. Organized into nine chapters, this volume begins with an overview of the contributions to the knowledge of membrane structure based on X-ray diffraction analysis. This text then examines the reactions of chlorophyll in model systems and the luminescence linked with light absorptions, which relate to the early events in photosynthesis. Other chapters relate spectroscopic and EPR measurements to redox changes linked with energy coupling in the mitochondrial electron carriers. This book discusses as well the role of soluble proteins in the energy transfer process of oxidative phosphorylation. The final chapter deals with the chemical and structural properties of the photoreceptors in the visual process. This book is a valuable resource for biophysicists, physiologists, biologists, biochemists, physical chemists, and research workers.

Table of Contents

  • List of Contributors


    Contents of Previous Volumes

    X-Ray Diffraction Studies on Biological Membranes

    I. Introduction

    II. Structure Analysis

    III. Surface Structure of Membranes

    IV. Lamellar Structure of Nerve Myelin

    V. Lamellar Structure of Retinal Photoreceptors

    VI. Oriented Membrane Preparations

    VII. Membrane Dispersions

    VIII. The Arrangement of the Lipid Hydrocarbon Chains

    IX. The Localization of the Terminal Methyl Groups

    X. Summary and Conclusions

    XI. General Perspective


    Chlorophyll and Light Energy Transduction in Photosynthesis

    I. Introduction

    II. Chlorophyll as Electron Donor-Acceptor

    III. Endogamous Chlorophyll Dimers and Oligomers

    IV. Visible Absorption Spectra of Chlorophyll Oligomers and the Nature of Antenna Chlorophyll

    V. Exogamous Chlorophyll-Nucleophile Adducts

    VI. Photoactivity of Chlorophyll Species

    VII. ESR of in Vivo Active Center Chlorophyll

    VIII. Chlorophyll Model for Conversion of Light


    Chemically and Physically Induced Luminescence as a Probe of Photosynthetic Mechanisms

    I. Introduction

    II. Luminescence Induced by an Acid-Base Transition

    III. Various Other Chemiluminescences

    IV. Thermoluminescence

    V. Ferricyanide-Induced Luminescence

    VI. Salt-Induced Luminescence

    VII. Flash Activation of Luminescence

    VIII. Conclusion


    The Reducing Side of Photosystem I

    I. Introduction

    II. FRS, ORS, and SL-ETH

    III. CRS

    IV. P430, Bound NHI, and Photoredoxin

    V. "310" Factor

    VI. D-2 Factor

    VII. Phosphodoxin

    VIII. Protein Factor

    IX. Concluding Remarks


    The Chemistry of Vertebrate and Invertebrate Visual Photoreceptors

    I. Introduction

    II. The Structure of Visual Photoreceptor Cells

    III. Properties of Visual Pigments and Their Membranes

    IV. The Chromophore of Visual Pigments

    V. Photolysis of Visual Pigments

    VI. Other Retinal-Based Pigments

    VII. A Summing Up


    Mechanism of Actomyosin ATPase and the Problem of Muscle Contraction

    I. Introduction

    II. Some General Properties of Muscle

    III. Enzymatic Properties

    IV. Problem of Relaxation

    V. Enzyme Schemes and Contraction Models


    Energy-Transducing Components in Mitochondrial Respiration

    I. Introduction

    II. The Thermodynamic Behavior of Oxidation-Reduction Reactions

    III. The Oxidation-Reduction Potentials of the Components of Intact Mitochondria

    IV. The Dependence of the Half-Reduction Potentials of the Components on the Phosphate Potential

    V. A Thermodynamic Profile of the Respiratory Chain Components and the Energy Conservation Sites

    VI. Oxidation-Reduction Potentials in "Open" and "Potential Clamped" Systems

    VII. On the Nature of Respiratory Control

    VIII. Evidence for a Direct Involvement of the Oxidation-Reduction Components in Energy Transduction

    IX. Is an Intact Membrane Required for Energy Conservation?

    X. Summary

    Appendix I

    Appendix II


    Kinetics of Cytochromes b

    I. Introduction

    II. Kinetics of Oxidation of the Cytochromes b

    III. Kinetics of Reduction of the b Cytochromes

    IV. Behavior of the b Cytochromes in the Antimycin A-Inhibited System

    V. Behavior of the Cytochromes b at 0°C

    VI. Kinetic Studies on Succinate-Cytochrome C1 Reductase

    VII. Interpretation of the Reaction Kinetics of Cytochromes b

    VIII. Kinetic Behavior of Cytochromes b and the Energy Coupling Reactions

    IX. Summary


    Mitochondrial Coupling Factors

    I. Introduction

    II. Problems Encountered in the Isolation, Identification, and Assay of Coupling Factors

    III. Properties of Isolated Coupling Factors

    IV. Evidence for the Functional Role of Coupling Factors

    V. Structural Role of Coupling Factors

    VI. Alternative Approaches to the Identification, Isolation, and Characterization of Coupling Factors

    VII. Conclusions


    Author Index

    Subject Index

Product details

  • No. of pages: 390
  • Language: English
  • Copyright: © Academic Press 1973
  • Published: January 1, 1973
  • Imprint: Academic Press
  • eBook ISBN: 9781483216898

About the Editors

D. Rao Sanadi

Lester Packer

Lester Packer
Lester Packer received a PhD in Microbiology and Biochemistry in 1956 from Yale University. In 1961, he joined the University of California at Berkeley serving as Professor of Cell and Molecular Biology until 2000, and then was appointed Adjunct Professor, Pharmacology and Pharmaceutical Sciences, School of Pharmacy at the University of Southern California.

Dr Packer received numerous distinctions including three honorary doctoral degrees, several distinguished Professor appointments. He was awarded Chevalier de l’Ordre National du Merite (Knight of the French National Order of Merit) and later promoted to the rank of Officier. He served as President of the Society for Free Radical Research International (SFRRI), founder and Honorary President of the Oxygen Club of California.

He has edited numerous books and published research; some of the most cited articles have become classics in the field of free radical biology:

Dr Packer is a member of many professional societies and editorial boards. His research elucidated - the Antioxidant Network concept. Exogenous lipoic acid was discovered to be one of the most potent natural antioxidants and placed as the ultimate reductant or in the pecking order of the “Antioxidant Network” regenerating vitamins C and E and stimulating glutathione synthesis, thereby improving the overall cellular antioxidant defense. The Antioxidant Network is a concept addressing the cell’s redox status. He established a world-wide network of research programs by supporting and co-organizing conferences on free radical research and redox biology in Asia, Europe, and America.

Affiliations and Expertise

Department of Molecular Pharmacology and Toxicology, School of Pharmaceutical Sciences, University of Southern California, USA

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