Description Table of Contents Details Serial Volume Editors

Description

This volume is dedicated to a description of the instruments, samples, protocols, and analyses that belong to cryo-EM. It emphasizes the relatedness of the ideas, instrumentation, and methods underlying all cryo-EM approaches, which allow practitioners to easily move between them. Within each section, the articles are ordered according to the most common symmetry of the sample to which their methods are applied.

Key Features

* Includes time-tested core methods and new innovations applicable to any researcher
* Methods included are useful to both established researchers and newcomers to the field
* Relevant background and reference information given for procedures can be used as a guide

Readership

Biochemists, structural biologists, molecular biologists, cell biologists, and microbiologists

Table of Contents

  1. Fundamentals of three-dimensional reconstruction from projections

    2. Pawel A. Penczek

  2. Image Restoration in Cryo-electron Microscopy

    3. Pawel A. Penczek

  3. Resolution measures in molecular electron microscopy

    4. Pawel A. Penczek

  4. 3D reconstruction from 2D crystal image and diffraction data

    5. Andreas Schenk, Daniel Castaño-Díez, Bryant Gipson, Marcel Arheit, Xiangyan Zeng, and Henning Stahlberg

  5. Fourier-Bessel Reconstruction of Helical Assemblies

    6. David L Stokes, Ruben Diaz & William, J. Rice

  6. Reconstruction of Helical Filaments and Tubes

    7. Edward H Egelman

  7. Three-Dimensional Asymmetric Reconstruction of Tailed Bacteriophage

    8. Jinghua Tang, Robert S. Sinkovits, and Timothy S. Baker

  8. Single Particle Analysis at High Resolution

    9. Yao Cong and Steven J. Ludtke

  9. The Orthogonal Tilt Reconstruction method

    10. Andres Leschziner

  10. An introduction to maximum-likelihood methods in cryo-EM

    11. Fred J. Sigworth, Peter C. Doerschuk, Jose-Maria Carazo, and Sjors H.W. Scheres

  11. Classification of structural heterogeneity by maximum-likelihood methods

    12. Sjors H.W. Scheres

  12. Methods for three-dimensional reconstruction of heterogeneous assemblies

    13. Elena V Orlova, Helen R. Saibil

  13. Alignment of cryo-electron tomography datasets

    14. Fernando Amat, Daniel Casta˜no-Diez, Albert Lawrence, Farshid Moussavi, Hanspeter Winkler, & Mark Horowitz

  14. Correcting for the Ewald sphere in high resolution single particle reconstructions

    15. Grant J Jensen, Peter A. Leong, Xuekui Yu, & Z. Hong Zhou

  15. Software Tools For Molecular Microscopy: An Open-Text Wikibook

Bridget Carra

Details

No. of pages:
456
Language:
English
Copyright:
© 2010
Published:
Imprint:
Academic Press
eBook ISBN:
9780123849922
Print ISBN:
9780123849915

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