Cranio-Facial Growth in Man

Cranio-Facial Growth in Man

Proceedings of a Conference on Genetics, Bone Biology, and Analysis of Growth Data Held May 1–3, 1967, Ann Arbor, Michigan

1st Edition - January 1, 1971

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  • Editors: Robert E. Moyers, Wilton M. Krogman
  • eBook ISBN: 9781483151991

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Description

Cranio-Facial Growth in Man contains the proceedings of a Conference on Genetics, Bone Biology, and Analysis of Growth Data, held in Ann Arbor, Michigan on May 1-3, 1967. Contributors discuss the state of knowledge in the area of cranio-facial growth, with emphasis on three primary areas of cranio-facial research: bone biology, genetics, and analysis of growth data. This text consists of 19 chapters organized into six sections. After giving an overview of research on cranio-facial growth done at the National Institute of Dental Research (NIDR), this book turns its attention to the biology of bone. Topics covered in this section include the mechanisms of cartilage growth and replacement in endochondral ossification; the histological characteristics of bone that reflect mineral homeostasis; and modes of growth of the neurocranium. The reader is also introduced to the genetics of cranio-facial growth and techniques in processing and handling growth data. A chapter that evaluates methods and perspectives in cranio-facial research concludes the book. This book will serve as a useful guide to prospective and active investigators in the field of human biology, to graduate students in their selection of a meaningful research topic, and to the NIDR in terms of future program planning.

Table of Contents

  • Conference Participants

    Foreword

    Preface

    PART I: PRELUDE

    Chapter 1: Introduction to Conference

    DR. ROBERT E. MOYERS

    DR. WILTON M. KROGMAN

    DR. MOYERS

    Chapter 2: Role of Growth Research at the National Institute of Dental Research

    Publisher Summary

    NIDR’s Interest in Cranio-facial Research

    Research Projects related to Cranio-facial Growth

    Research Areas of Interest to NIDR

    Research Manpower Needs

    Conclusion

    PART II: THE BIOLOGY OF BONE

    Chapter 3: Introduction

    Chapter 4: The Mechanisms of Cartilage Growth and Replacement in Endochondral Ossification

    Publisher Summary

    Achondroplasia

    Rickets

    Discussion

    Chapter 5: Bone Morphology and Mineral Homeostasis

    Publisher Summary

    Discussion

    Chapter 6: Load and Electric Charge Relationships for Cortical Bone

    Publisher Summary

    Materials and Methods

    Area Measurement

    Hardness Test

    Histological Study

    Compression Tests

    Chemical Analysis

    Results

    Bone Tumors

    Discussion of Results

    Summary

    Discussion

    Chapter 7: Comparative Ontogeny and Cranio-facial Growth

    Publisher Summary

    The Development of the cranio-facial Area according to the Formal Anatomical Conception

    Inferences of the Homology Principle

    The Concept of Growth

    The Growth of the Elements in the cranio‐facial Region

    The Relation between the Elements

    Concluding Remarks

    Chapter 8: The Modes of Growth of the Neurocranium: The Growth of the Sphenoid Bone in Animals

    Publisher Summary

    Materials and Methods

    Observations

    Discussion

    Legend Abbreviations

    Key to Symbols used in Diagrams

    Chapter 9: Vertical Development of the Face — A Summary

    Publisher Summary

    Chapter 10: Ontogenetic Aspects of Cranio-facial Growth

    Publisher Summary

    Disciplinary Diversity

    Current Concepts and Problems

    Discussion

    Chapter 11: Some Characteristics of Cranio-facial Growth Cartilages

    Publisher Summary

    Structure

    Function

    Cranial Base Synchondroses

    The Subcutaneous Transplants (Fig. 5)

    Intracerebral Transplants (Fig. 6)

    Whole Cranial Base Transplants

    Condylar Cartilage Subcutaneous Transplants

    Intracerebral Transplants

    Long Bone Epiphyseal Cartilage

    Discussion

    Addendum

    PART III: GENETICS OF CRANIO-FACIAL GROWTH

    Chapter 12: Introduction

    Chapter 13: The Threshold Model: Uses and Limitations

    Publisher Summary

    Inferences

    Generality

    Threshold Model

    Mendelian Arithmetic

    Summary

    Discussion

    Chapter 14: Genetic and Environmental Variation in the Growth of Mice

    Publisher Summary

    Theoretical Basis

    Experiment and Results

    Summary

    Chapter 15: The Statistical Treatment of Data with Genetic Structure

    Publisher Summary

    Some General Ideas of Data Analysis

    The Data Available

    The Biometrical Approach: The Covariances of Relatives

    The Weaknesses of the Common Twin Statistical Methodology

    Population Structure

    The Role of Environment

    Joint Variation of Attributes

    The Logic of Classical Qualitative Genetics

    Some Remarks about the Approaches

    Discussion

    Chapter 16: The Genetic Aspects of Cranio-facial Growth

    Publisher Summary

    Pre-1900 Studies in Heredity

    Genetics: 1900 and After

    Genetic Characteristics of the Cranio-facial Complex

    Population Differences

    Family-Fraternity Differences

    Twin Data

    Chromosomal Aberrations

    Conclusions

    Discussion

    Chapter 17: Genetic Factors and Classification of Cranio-facial Anomalies derived from a Perturbation of the First Branchial Arch

    Publisher Summary

    Otocephalia

    Mandibulofacial Dysostosis

    Mandibular Dysostosis. Oto-mandibular Dysostosis

    Oculo-auricular Dysostosis

    Mandibulo-oculo-facial Dysmorphia

    Mandibulo-oculo-facial Dyscephalia

    Oculo-vertebral Dysplasia

    Oto-vertebral Dysplasia

    Cranio-palpebro-irido-cutaneous Dysplasia with Labyrinthine Deafness and other Congenital Anomalies

    Cervico-oculo-facial Dysmorphia with Deafness. Cervico-oculo-acoustic Syndrome

    Paralysis of the Facial Nerve, Middle Ear Deafness (Malformations of the Ossicles), Preauricular Appendages, Preauricular and Cervical Fistulas

    Microgenia, Glossoptosis and Cleft Palate

    Oculo-dento-digital Dysplasia with Microphthalmia

    Pygo-phalangeal Dyscrania with Microphthalmia

    Congenital Mandibular Dysostosis with Peromelia

    Oral-facial-digital (OFD) Syndrome

    Maxillofacial Dysostosis

    Acro-facial Dysostosis

    Cranio-mandibulo-facial Dysplasia with Dwarfism

    Conclusions

    PART IV: ANALYSIS OF GROWTH DATA

    Chapter 18: Introduction

    Chapter 19: Applications of Multivariate Analysis to Cranio-facial Growth

    Publisher Summary

    Chapter 20: A Computer Model for Bone Growth

    Publisher Summary

    Discussion

    Chapter 21: Problems in the Statistical Inspection of Cranio-facial Variables during Growth and Development

    Publisher Summary

    Summary

    Discussion

    Chapter 22: Factor Analysis of Cranio-facial Variables

    Publisher Summary

    Concepts

    Application

    Conclusion

    PART V: INTEGRATION AND APPLICATION

    Introduction

    Seminar 1: Form and Function

    Genetics and Growth

    Theoretical Biology

    Specific Comments

    Seminar 2: Prediction of Cranio-facial Growth

    DR. MOYERS

    DR. WOODSIDE

    DR. MOYERS

    DR. TANNER

    DR. JOHNSTON

    DR. TANNER

    DR. MOYERS

    DR. WOODSIDE

    DR. MOYERS

    DR. WOODSIDE

    DR. MOYERS

    DR. RAO

    DR. KEMPTHORNE

    DR. RAO

    DR. JOHNSTON

    DR. MOYERS

    DR. TANNER

    DR. HOYTE

    DR. MOYERS

    DR. WOODSIDE

    DR. MOYERS

    DR. TANNER

    DR. KEMPTHORNE

    DR. MOYERS

    DR. JOHNSTON

    DR. ROCHE

    DR. RYAN

    DR. TANNER

    DR. KLEIN

    DR. COBEN

    DR. KEMPTHORNE

    DR. MOYERS

    DR. RAO

    DR. MOSS

    DR. KROGMAN

    DR. KEMPTHORNE

    DR. TANNER

    DR. RAO

    DR. TANNER

    DR. MOYERS

    DR. RAO

    DR. WITKOP

    DR. MOYERS

    DR. WITKOP

    DR. WOODSIDE

    DR. JOHNSTON

    DR. TANNER

    DR. KEMPTHORNE

    DR. TANNER

    DR. WOODSIDE

    DR. MOSS

    DR. WOODSIDE

    DR. MOSS

    DR. WOODSIDE

    DR. MOYERS

    DR. WOODSIDE

    DR. JOHNSTON

    DR. KEMPTHORNE

    DR. HARVOLD

    DR. MOYERS

    DR. WOODSIDE

    DR. MOYERS

    DR. TANNER

    DR. MOYERS

    DR. MOORREES

    DR. JOHNSTON

    DR. TANNER

    DR. RAO

    DR. COBEN

    DR. BURDI

    DR. MOORE

    DR. JOHNSTON

    DR. ROCHE

    DR. JOHNSTON

    DR. LASKIN

    DR. TANNER

    DR. MOYERS

    DR. FROST

    DR. CRAVEN

    DR. COBEN

    DR. FALCONER

    DR. TANNER

    DR. MOYERS

    Seminar 3: New Techniques in Processing and Handling Growth Data

    DR. WALKER

    DR. WESTERVELT

    DR. MOSS

    DR. WESTERVELT

    QUESTIONER

    DR. WESTERVELT

    DR. MOSS

    DR. WESTERVELT

    DR. MOSS

    DR. WESTERVELT

    DR. WALKER

    DR. LEDLEY

    DR. WALKER

    DR. MOSS

    DR. LEDLEY

    DR. MOSS

    DR. LEDLEY

    DR. MOSS

    DR. LEDLEY

    DR. WALKER

    QUESTIONER

    DR. WALKER

    QUESTIONER

    DR. WALKER

    DR. HOWELLS

    DR. WALKER

    QUESTIONER

    DR. WALKER

    QUESTION

    DR. WALKER

    DR. BOSMA

    DR. WALKER

    DR. BOSMA

    DR. WALKER

    DR. BOSMA

    DR. WALKER

    DR. BOSMA

    DR. WALKER

    DR. MOSS

    DR. WALKER

    DR. MOSS

    DR. WALKER

    DR. MOSS

    DR. WALKER

    DR. MOSS

    QUESTIONER

    DR. KROGMAN

    DR. GRAINGER

    DR. WALKER

    DR. WESTERVELT

    DR. LENT JOHNSTON

    DR. WALKER

    DR. LEDLEY

    DR. BOSMA

    DR. WALKER

    DR. HUNTER

    DR. WALKER

    DR. SOLOW

    PART VI: NEW DIRECTIONS–NEW HORIZONS

    Introduction

    Pathfinder Paper: Bone

    Publisher Summary

    Pathfinder Paper: Genetics

    Publisher Summary

    Methods and Perspectives in Cranio-facial Research

    Publisher Summary

    Index

Product details

  • No. of pages: 370
  • Language: English
  • Copyright: © Pergamon 1971
  • Published: January 1, 1971
  • Imprint: Pergamon
  • eBook ISBN: 9781483151991

About the Editors

Robert E. Moyers

Wilton M. Krogman

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