Contemporary Chemical Approaches for Green and Sustainable Drugs

Contemporary Chemical Approaches for Green and Sustainable Drugs

1st Edition - June 1, 2022

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  • Editor: Marianna Torok
  • Paperback ISBN: 9780128222485

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Description

Contemporary Chemical Approaches for Green and Sustainable Drugs provides readers with the knowledge they need to integrate sustainable approaches into their work. Sections cover different aspects of green and sustainable drug development from design to disposal, including computer-aided drug design, green resourcing of drugs and drug candidates, an overview of the health concerns of pharmaceutical pollution, and a survey of potential chemical methods for its reduction. Drawing together the knowledge of a global team of experts, this book provides an inclusive overview of the chemical tools and approaches available for minimizing the negative environmental impact of current and newly developed drugs. This will be a useful guide for all academic and industrial researchers across green and sustainable chemistry, medicinal chemistry, environmental chemistry and pharmaceutical science.

Key Features

  • Provides an integrative overview of the environmental risks of drugs and drug by products to support chemists in pre-emptively addressing these issues
  • Highlights the advantages of computer-aided drug design, green and sustainable sourcing, and novel methods for the production of safer, more effective drugs
  • Presents individual chapters written by renowned experts with diverse backgrounds
  • Reflects research in practice through selected case studies and extensive state-of-the-art reference sections to serve as a starting point in the design of any specialized environmentally-conscious medicinal chemistry project

Readership

Industrial/academic researchers, process scientists, chemical and bioengineers interested in green and sustainable chemistry, drug discovery and development. Scientists traditionally working outside of green chemistry, such as biochemists and computational chemists, whose work with powerful, advanced tools can significantly contribute to green and sustainable medicinal chemistry. Pharmaceutical industry, government officials (environmental agencies etc.) and managerial level executives in related industries and health care units. It could be used in graduate level education as a textbook, or as a supplemental textbook in medicinal chemistry, green chemistry or environmental chemistry courses

Table of Contents

  • 1. Using the Zebrafish Model System to Identify the Health Effects of Pharmaceutical Pollutants

    2. Analysis of Pharmaceuticals in the Environment

    3. Leaking of Antibiotics in the Aquatic Environment

    4. Advances in Drug Development with the Application of Artificial Intelligence

    5. Virtual Screening Techniques in Pharmaceutical Research

    6. In Silico Modeling of Environmental Toxicity of Drugs

    7. Sustainable Separations in Pharmaceutical Manufacturing

    8. Green Synthetic Methods in Drug Discovery and Development

    9. Green Metrics of Drug Synthesis

    10. Green chemistry approaches to drugs that treat epidemic and pandemic diseases

    11. Dynamic Effects of Organic Molecules for Drug Delivery in Micelles

    12. Antibody-Drug Conjugates for Targeted Delivery

    13. Green Peptide-based Drugs

    14. The Multitarget Approach as a Green Tool in Medicinal Chemistry

    15. Directed Evolution: A New Powerful Tool in Drug Development

    16. Conventional and Advanced Treatment Methods for the Removal of Pharmaceuticals and Related Compounds in Wastewater

Product details

  • No. of pages: 500
  • Language: English
  • Copyright: © Elsevier 2022
  • Published: June 1, 2022
  • Imprint: Elsevier
  • Paperback ISBN: 9780128222485

About the Editor

Marianna Torok

Dr Marianna Török complete her studies in Physical Chemistry and Biochemistry at the University of Szeged (Hungary), University of Southern California Los Angeles (USA) and Massachusetts Institute of Technology (USA). She is an associate professor at the Department of Chemistry, University of Massachusetts Boston (USA), a public university strongly committed to Green Chemistry education and research, and the first school to offer a doctoral degree via the PhD in Chemistry/Green Chemistry Track. Her research interest includes the interconnection of Medicinal Chemistry and Green Chemistry, and she is a co-author of several reviews and research articles in this field

Affiliations and Expertise

Associate Professor, Department of Chemistry, University of Massachusetts, Boston, USA

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