An explosive increase in the knowledge of the effects of chemical and physical agents on biological systems has led to an increased understanding of normal cellular functions and the consequences of their perturbations. The 14-volume Second Edition of Comprehensive Toxicology has been revised and updated to reflect new advances in toxicology research, including content by some of the leading researchers in the field. It remains the premier resource for toxicologists in academia, medicine, and corporations.

Comprehensive Toxicology Second Edition provides a unique organ-systems structure that allows the user to explore the toxic effects of various substances on each human system, aiding in providing diagnoses and proving essential in situations where the toxic substance is unknown but its effects on a system are obvious. Comprehensive Toxicology Second Edition is the most complete and valuable toxicology work available to researchers today.

Key Features

  • Contents updated and revised to reflect developments in toxicology research
  • Organized with a unique organ-system approach
  • Features full color throughout
  • Available electronically on, as well as in a limited-edition print version


Toxicology researchers, academic and medical practitioners, food science researchers, environmental researchers and consultants, forensic scientists, and occupational health and safety institutes

Table of Contents

Brief Contents

Volume 1 - General Principles (Bond)
Volume 2 - Cellular and Molecular Toxicology (Ramos)
Volume 3 - Toxicology Testing and Evaluation (Lamb)
Volume 4 - Biotransformation (Guengerich)
Volume 5 - Immune System Toxicology (Lawrence)
Volume 6 - Cardiovascular Toxicology (Walker)
Volume 7 - Renal Toxicology (Schnellmann)
Volume 8 - Respiratory Toxicology (Yost)
Volume 9 - Hepatic Toxicology (Roth/Ganey)
Volume 10 - Gastrointestinal Toxicology (Hooser)
Volume 11 - Reproductive and Endocrine Toxicology (Richburg/Hoyer)
Volume 12 - Developmental Toxicology (Knudsen/Daston)
Volume 13 - Nervous System and Behavioural Toxicology (Philbert)
Volume 14 - Carcinogenesis (Roberts)


Elsevier Science
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