Biophysics is a rapidly-evolving interdisciplinary science that applies theories and methods of the physical sciences to questions of biology. Biophysics encompasses many disciplines, including physics, chemistry, mathematics, biology, biochemistry, medicine, pharmacology, physiology, and neuroscience, and it is essential that scientists working in these varied fields are able to understand each other's research. Comprehensive Biophysics will help bridge that communication gap.

Written by a team of researchers at the forefront of their respective fields, under the guidance of Chief Editor Edward Egelman, Comprehensive Biophysics provides definitive introductions to a broad array of topics, uniting different areas of biophysics research - from the physical techniques for studying macromolecular structure to protein folding, muscle and molecular motors, cell biophysics, bioenergetics and more. The result is this comprehensive scientific resource - a valuable tool both for helping researchers come to grips quickly with material from related biophysics fields outside their areas of expertise, and for reinforcing their existing knowledge.

Key Features

    • Biophysical research today encompasses many areas of biology. These studies do not necessarily share a unique identifying factor. This work unites the different areas of research and allows users, regardless of their background, to navigate through the most essential concepts with ease, saving them time and vastly improving their understanding.
    • The field of biophysics counts several journals that are directly and indirectly concerned with the field. There is no reference work that encompasses the entire field and unites the different areas of research through deep foundational reviews. Comprehensive Biophysics fills this vacuum, being a definitive work on biophysics. It will help users apply context to the diverse journal literature offering, and aid them in identifying areas for further research.
    • Chief Editor Edward Egelman (E-I-C, Biophysical Journal) has assembled an impressive, world-class team of Volume Editors and Contributing Authors. Each chapter has been painstakingly reviewed and checked for consistent high quality. The result is an authoritative overview which ties the literature together and provides the user with a reliable background information and citation resource.


    Researchers, advanced undergraduate and graduate students, postdoctoral fellows, senior investigators, corporate customers (such as biotech companies) and libraries from Physics, Chemistry and Life Sciences departments.

    Table of Contents

    Volume 1: Biophysical Techniques for Structural Characterization of Macromolecules (Jane Dyson, The Scripps Research Institute, CA, USA)

    Volume 2: Biophysical Techniques for Characterization of Cells (Petra Schwille, TU Dresden, Dresden, Germany)

    Volume 3: The Folding of Proteins and Nucleic Acids (Valerie Daggett, University of Washington, WA, USA)

    Volume 4: Molecular Motors and Motility (Yale Goldman & E. Michael Ostap, University of Pennsylvania, PA, USA)

    Volume 5: Membranes (Lukas Tamm, University of Virginia, VA, USA)

    Volume 6: Channels (Mauricio Montal, University of California, San Diego, CA, USA)

    Volume 7: Cell Biophysics (Denis Wirtz, Johns Hopkins University, Baltimore, MD, USA)

    Volume 8: Bioenergetics (Stuart Ferguson, University of Oxford, UK)

    Volume 9: Simulation and Modeling (Harel Weinstein, Weill Cornell Medical College, NY, USA)


    Full list of contents:

    Cantor and Schimmel - 30 Years Later
    Efficient Strategies for Production of Eukaryotic Proteins
    X-ray Crystallography: Crystallization
    X-ray crystallography | Data Collection Strategies and Resources
    X-ray crystallography | Phasing of X-ray Data
    X-ray crystallography | Refinement of X-ray Crystal Structures
    X-ray crystallography | Structure Validation and Analysis
    NMR Spectroscopy | Solution methods
    NMR Spectroscopy | Solid state NMR methods
    NMR Spectroscopy | Membrane protein methods: The hybrid solution/solid-state NMR method
    NMR Spectroscopy | Labeling techniques
    NMR Spectroscopy | NMR Relaxation methods
    Electron microscopy | 2D crystals
    Electron microscopy | Cryo-Electron Microscopy and Tomography of Viru


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    © 2012
    Academic Press
    Not Applicable ISBN:
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