The Complement System: A Brief Overview:
Activation of C.
Physiological Roles of C.
Involvement of C in Pathology.
Why a Book on C Regulators?
Regulation in the Complement System:
Control of Activation Pathways.
Control in the Membrane Attack Pathway.
Control of the Anaphylactic Peptides.
Regulation in the Activation Pathways:
Regulation of C1.
Regulators Encoded in the RCA Gene Cluster.
Other Regulators of the Activation Pathways.
Regulation in the Terminal Pathway:
Fluid-Phase Regulators of the Terminal Pathway.
Membrane Regulators of the Terminal Pathway.
Recovery from C Membrane Attack.
Deficiencies of Complement Regulators:
Introduction, Deficiency of C1 Inhibitor (C1inh).
Deficiencies of Fluid-Phase C3 Convertase Regulators.
Deficiencies of Fluid-Phase Membrane Attack Pathway Regulators.
Deficiencies of Membrane Regulators of C.
Complement Regulation in the Reproductive System:
Role of C Inhibitors in the Protection of Sperm.
Role of C Regulators in Protection of the Fetus.
The Role of MCP in Fertilization.
Complement Regulators and Micro-Organisms:
Complement Regulators as Receptors for Microorgansims.
Hijacking of Complement Regulators by Microorganisms.