Coatings for Biomedical Applications

Coatings for Biomedical Applications

1st Edition - February 22, 2012

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  • Editor: Mike Driver
  • Hardcover ISBN: 9781845695682
  • eBook ISBN: 9780857093677

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The biomaterials sector is rapidly expanding and significant advances have been made in the technology of biomedical coatings and materials, which provide a means to improve the wear of joints, change the biological interaction between implant and host and combine the properties of various materials to improve device performance. Coatings for biomedical applications provides an extensive review of coating types and surface modifications for biomedical applications.The first part of the book explores a range of coating types and their biomedical applications. Chapters look at hydrophilic, mineral and pyrolytic carbon coatings in and ex vivo orthopaedic applications and finally at surface modification and preparation techniques. Part two presents case studies of orthopaedic and ophthalmic coatings, and biomedical applications including vascular stents, cardiopulomonary by-pass equipment and ventricular assist devices.With its clear structure and comprehensive review of research, Coatings for biomedical applications is a valuable resource to researchers, scientists and engineers in the biomedical industry. It will also benefit anyone studying or working within the biomedical sector, particularly those specialising in biomedical coatings.

Key Features

  • Provides an extensive review of coating types and surface modifications for biomedical applications
  • Chapters look at hydrophilic coatings for biomedical applications in and ex vivo, mineral coatings for orthopaedic applications, pyrolytic carbon coating and other commonly-used biomedical coatings
  • Presents case studies of orthopaedic and ophthalmic coatings, and biomedical applications including vascular stents, cardiopulomonary by-pass equipment and ventricular assist devices


Medical device designers; biomedical engineers; medical products manufacturers.

Table of Contents

  • Contributor contact details


    Part I: Coating types and applications

    Chapter 1: Hydrophilic coatings for biomedical applications in and ex vivo


    1.1 Introduction

    1.2 Examples of hydrophilic coatings

    1.3 Applications for hydrophilic coatings in the clinical environment (ex vivo)

    1.4 Applications for hydrophilic coatings in the clinical environment (in vivo)

    1.5 Conclusions and future trends

    1.6 Sources of further information

    1.8 Appendix: list of suppliers of hydrophilic coatings for biomedical devices

    Chapter 2: Mineral coatings for orthopaedic applications


    2.1 Introduction

    2.2 Important characteristics of mineral coatings

    2.3 Coating methods

    2.4 Clinical studies

    2.5 Future trends

    2.6 Sources of further information

    Chapter 3: Other commonly used biomedical coatings: pyrolytic carbon coatings


    3.1 Introduction

    3.2 Carbon solid materials

    3.3 Carbon film coatings

    3.4 Pyrolytic carbon coatings

    3.5 Conclusion

    Chapter 4: Electrochemical surface modifications of titanium and titanium alloys for biomedical applications


    4.1 Introduction

    4.2 Electrochemical treatments

    4.3 Future trends in chemical and electrochemical treatments

    4.4 Conclusions

    4.5 Acknowledgements

    4.7 Appendix: list of abbreviations

    Chapter 5: Surface preparation techniques for biomedical applications


    5.1 Introduction

    5.2 Sonication

    5.3 Mechanical polishing

    5.4 Electropolishing

    5.5 Chemical etching

    5.6 Plasma treatment

    5.7 Priming

    5.8 Future trends

    5.9 Sources of further information

    Chapter 6: Characterisation of biomedical coatings


    6.1 Introduction

    6.2 Surfaces, concepts and techniques

    6.3 Contact angle

    6.4 Analysis of adhesion

    6.5 Scanning probe microscopy

    6.6 Confocal microscopy

    6.7 Scanning electron microscopy and transmission electron microscopy

    6.8 Spectroscopic methods

    6.9 Optical detection methods

    6.10 Neutron reflectivity

    6.11 Other techniques

    6.12 Future trends

    6.13 Sources of further information

    Part II: Case studies

    Chapter 7: Coatings for cardiovascular devices: coronary stents


    7.1 Introduction: heart disease its treatments

    7.2 Artery structure and mechanism of restenosis

    7.3 Commercial drug-eluting stent (DES) systems

    7.4 Increased use of DES and concerns surrounding stent thrombosis

    7.5 Second generation DES systems

    7.6 Other approaches and future trends

    7.7 Conclusions

    Chapter 8: Coatings for cardiovascular devices: extracorporeal circuits


    8.1 Background of coatings for extracorporeal circulation

    8.2 Coatings for left-heart bypass

    8.3 Coatings for cardiopulmonary bypass

    8.4 Coatings for mechanical circulatory support

    8.5 Coatings for other devices in cardiothoracic surgery

    8.6 Conclusions

    Chapter 9: Surface coatings for ventricular assist devices


    9.1 Introduction

    9.2 Ventricular assist devices (VADs)

    9.3 Hemocompatible surface coatings for VADs

    9.4 Future trends

    9.5 Conclusions

    Chapter 10: Orthopaedic coatings


    10.1 History of joint replacement

    10.2 Development of joint replacement prostheses

    10.3 Development of cementless fixation

    10.4 Thermal spray coating techniques

    10.5 Coating characteristics

    10.6 Alternative coating methods

    10.7 Clinical experience

    10.8 Acknowledgements

    Chapter 11: Surface coatings in urology


    11.1 Introduction

    11.2 Indwelling bladder catheters

    11.3 Biofilm formation on implanted urological devices

    11.4 Challenges in controlling catheter-associated urinary tract infection

    11.5 Developments in antimicrobial catheters

    11.6 The catheter encrustation problem

    11.7 Ureteric stents

    11.8 Conclusions

    Chapter 12: Ophthalmic coatings


    12.1 Introduction

    12.2 Contact lenses

    12.3 Artificial cornea

    12.4 Intraocular lenses

    12.5 Other ophthalmic devices

    12.6 Conclusions


Product details

  • No. of pages: 376
  • Language: English
  • Copyright: © Woodhead Publishing 2012
  • Published: February 22, 2012
  • Imprint: Woodhead Publishing
  • Hardcover ISBN: 9781845695682
  • eBook ISBN: 9780857093677

About the Editor

Mike Driver

Mike Driver is Biomaterials Business Director at Vertellus Specialties UK Ltd. He has been instrumental in the development of new materials for contact lenses and biocompatible coatings for medical devices.

Affiliations and Expertise

Vertellus, UK

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