Description

Current Topics in Membranes is targeted towards scientists and researchers in biochemistry and molecular and cellular biology, providing the necessary membrane research to assist them in discovering the current state of a particular field and in learning where that field is heading. In this volume, researchers are encouraged to fully explore topics and research related to co-transport systems. The authors and editors associated with the Current Topics in Membranes series are recognized as world-renowned scientists in their respective fields, making CTM one of the premier serials on membranes.

Key Features

  • Field is cutting-edge and a lot of the information is new to research community
  • Wide breadth of topic coverage
  • Contributors of high renown and expertise

Readership

Scientists and researchers in biochemistry and molecular and cellular biology

Table of Contents

Current Topics In Membranes

Dedication

Contributors

Preface

Previous Volumes In Series

Chapter One. Amino Acid Secondary Transporters

1 Classification of Amino Acid Transporters

2 Human SLCs Involved in Amino Acid and Neurotransmitter Transport

3 The Structural APCS: Mechanistic Concepts

4 Ions and Directionality in Amino Acid Transport

5 Regulation in APCS Fold Transporters

Acknowledgments

References

Chapter Two. SLC5 and SLC2 Transporters in Epithelia—Cellular Role and Molecular Mechanisms

1 Introduction

2 Physiological Significance and Molecular Characteristics of Epithelial Sugar Transport

3 Sodium–Glucose Symport as the Basis for Active Transepithelial Glucose Transport

4 Cloning of Transporter cDNAs, Sequence Homologies and Conserved Amino Acids

5 Transporter Domains, Their Arrangement in the Membrane and Their Function

6 Crystal Structures and Homology Models of Members of SLC5 and SLC2

7 Regulation of Transporter Activity

8 Synopsis

References

Chapter Three. SLC4A Transporters

1 Introduction

2 SLC4A Transporters

3 Ion Transport Properties

4 Structure of SLC4A Transporters

5 Interaction with Other Proteins

6 Conclusion

Acknowledgments

References

Chapter Four. The SLC10 Carrier Family

1 Introduction

2 The SLC10 Family

3 The Liver Bile Salt Transporter SLC10A1 (NTCP)

4 The Ileal Bile Salt Transporter ASBT (SLC10A2)

5 Novel Members of the SLC10 Family

6 Conclusion

Abbreviations

References

Chapter Five. H+-Coupled Divalent Metal-Ion Transporter-1

1 Introduction and History

2 Animal Models

3 Mutations in Human DMT1

4 Functional Properties of DMT1

5 Regulation of the Cellular Expression of

Details

No. of pages:
416
Language:
English
Copyright:
© 2012
Published:
Imprint:
Academic Press
Electronic ISBN:
9780123946065
Print ISBN:
9780123943163

About the serial-volume-editor