This second edition updates the burgeoning field of regeneration in the Central Nervous System (CNS) from molecular, systems, and disease-based perspective. While the book covers numerous areas in detail, special emphasis is given to discussions of movement disorders such as Parkinson’s disease, Alzheimer’s disease, and spinal cord injury.
- Incorporates information gained from cutting-edge photomicroscopy techniques
- Includes current information on clinical trials
- Presents chapters on stem cells and other novel treatments for diseases of the CNS
Neuroscientists and clinical research neurologists.
CNS Regeneration, 2nd ed focuses on leading current neurological disease models and methods for promoting central nervous system regeneration. The book reviews key features of central nervous system injury and degeneration, then unites advances in neuroscience with novel medical strategies. Therapies that are currently being applied in clinical trials for stroke and spinal cord injury, as well as neurological diseases such as Parkinson’s disease, Alzheimer’s disease, and Huntington’s disease, are reviewed by experts in the field of basic and clinical neuroscience.
Organized into multiple sections, section one focuses on responses of the nervous system to cellular and axonal insults, identifying issues critical to mediating nervous system repair. Responses of neurons, axons, and glia to injury are described together with the deleterious effects of factors such as free radicals and excitotoxins. Section two identifies tools for promoting regeneration of the CNS including neurotrophic factors, and primary and immortalized pro-genitor cells. Subsequent chapters discuss the application of…Huntington’s disease, novel therapies for spinal…demyelination, and the design of clinical trials…in rehabilitation with neural repair.
This second edition provides some of the most current and promising approaches to understanding CNS regeneration generally, and to the application of these findings to treatment of neurological diseases, stroke, and spinal cord injury. This editions includes new chapters on stem cell therapy for brain tumors and Parkinson’s Disease. Written by leaders in the field of neuronal regeneration, this will be a valuable addition to scientists and practitioners in neuroscience.
Key features • Covers basic research and medical applications • Translates advances to treatment for specific disorders • Includes exciting advances in stem cell research and neurotrophic factors
- No. of pages:
- © Academic Press 2008
- 27th December 2007
- Academic Press
- eBook ISBN:
- Hardcover ISBN:
Rush-Presbyterian Medical Center, Chicago, Illinois, U.S.A.
University of California, San Diego, U.S.A.
Review of 1st edition "This is a well compiled and thoroughly edited and written text by the leaders in the field of neural regeneration...an excellent overview. Reasonably priced, this is a valuable addition to a neuroscientist's bookshelf." -Doody's Publishing Services, 4 Star Review