CNS Regeneration, 2nd ed focuses on leading current neurological disease
models and methods for promoting central nervous system regeneration. The book reviews
key features of central nervous system injury and degeneration, then unites advances in
neuroscience with novel medical strategies. Therapies that are currently being applied in
clinical trials for stroke and spinal cord injury, as well as neurological diseases such as Parkinson’s
disease, Alzheimer’s disease, and Huntington’s disease, are reviewed by experts in the
field of basic and clinical neuroscience.
Organized into multiple sections, section one focuses on responses of the nervous system
to cellular and axonal insults, identifying issues critical to mediating nervous system repair.
Responses of neurons, axons, and glia to injury are described together with the deleterious
effects of factors such as free radicals and excitotoxins. Section two identifies tools for
promoting regeneration of the CNS including neurotrophic factors, and primary and immortalized
pro-genitor cells. Subsequent chapters discuss the application of…Huntington’s disease,
novel therapies for spinal…demyelination, and the design of clinical trials…in rehabilitation
with neural repair.
This second edition provides some of the most current and promising approaches to understanding
CNS regeneration generally, and to the application of these findings to treatment of
neurological diseases, stroke, and spinal cord injury. This editions includes new chapters on
stem cell therapy for brain tumors and Parkinson’s Disease. Written by leaders in the field
of neuronal regeneration, this will be a valuable addition to scientists and practitioners in