Clinical PET/MRI

Clinical PET/MRI

1st Edition - September 7, 2022

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  • Editor: Onofrio Catalano
  • eBook ISBN: 9780323885386

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Clinical PET/MR presents the state-of-the-art of PET/MR, guiding the reader from how to scan patients, how to read and report the studies, and how keep an eye on what is clinically relevant for a patient’s care. Each chapter starts with the clinical scenario and then moves to pertinent imaging, addressing the need of a clinical PET/MR book written by world experts in both clinical and imaging fields. It discusses the clinical application of PET/MR in diverse subspecialties such as head and neck, neurology, cardiovascular, pediatrics, chest, bone, hematology, breast, hepatobiliary pancreatic, genitourinary, gynecology, and gastrointestinal tract. This book is a valuable resource for radiologists, oncologists and members of the biomedical field who need to learn more about clinical applications of PET/MR.

Key Features

  • Presents a description of robust acquisition protocols to teach readers how to scan PET/MR patients, from tracers to sequences
  • Provides a clinical background section in each chapter to help readers focus on the real clinical issues that need to be addressed in the medical report
  • Written by world authorities in the field in a didactic manner to describe the real status of imaging


Researchers in radiology, radiologists, clinicians, oncologists

Table of Contents

  • Cover image
  • Title page
  • Table of Contents
  • Copyright
  • Dedication
  • Contributors
  • Chapter 1. PET/MRI: technical and methodological aspects
  • Introduction
  • Integrated PET/MRI systems
  • Traditional approaches to address challenges and enable opportunities
  • Deep learning approaches to address challenges and enable opportunities
  • Conclusions
  • Chapter 2. Radiopharmaceuticals and contrast agents
  • Introduction to PET radiopharmaceuticals and radionuclides
  • Selected clinically-relevant PET radiopharmaceuticals
  • Common clinically-utilized MRI contrast agents
  • Chapter 3. Head and neck imaging
  • Introduction
  • Current role of imaging in patients with known or suspected head and neck cancer
  • PET/MRI in head and neck cancer
  • Conclusion
  • Chapter 4. Neurologic imaging
  • Introduction
  • Protocols
  • Neurodegenerative disorders
  • Brain tumors
  • Epilepsy
  • Chapter 5. Cardiovascular imaging
  • Introduction
  • Detection of coronary artery disease
  • Assessment of tissue viability and infarct size
  • Assessment of inflammatory response to acute ischemic injury
  • Myocarditis
  • Assessment of cardiac amyloidosis
  • Sarcoidosis
  • Assessment of cardiac fibrosis
  • Technical challenges of cardiac PET/MR
  • Summary
  • Chapter 6. Pediatrics imaging
  • Introduction
  • Imaging protocol
  • Lymphomas
  • Ewing sarcoma
  • Osteosarcoma
  • Soft tissue sarcomas
  • Malignant peripheral nerve sheath tumors
  • Neuroblastoma
  • Other adrenal gland tumors
  • Neuroendocrine tumors
  • Germ cell tumors
  • Renal tumors
  • Malignant liver tumors
  • Langerhans cell histiocytosis
  • Summary and conclusion
  • Chapter 7. Thoracic imaging
  • Clinical management of malignancies of the chest
  • PET/MRI of malignancies of the chest
  • Chapter 8. Musculoskeletal imaging
  • Primary bone and soft tissue malignancies
  • Primary bone and soft tissue lesions
  • Metastatic disease to the skeleton
  • Nononcological indications
  • Chapter 9. Hematologic imaging
  • Introduction
  • PET/MRI protocols overview
  • Lymphoma
  • Myeloma
  • Novel PET tracers in blood cancers
  • Summary
  • Chapter 10. Breast imaging
  • Introduction
  • Breast PET/MRI acquisition technique
  • Imaging
  • Future perspectives: radiomics and artificial intelligence
  • Pitfalls and strengths
  • Chapter 11. Hepatobiliary and pancreatic imaging
  • Introduction
  • Protocols
  • Primary hepatic malignancies
  • Pancreatic cancer
  • Liver metastases
  • Miscellaneous pancreaticobiliary malignancies
  • Chapter 12. Genitourinary imaging
  • Introduction
  • PET/MRI protocol
  • Adrenal masses
  • Renal cell carcinoma
  • Urothelial cancer
  • Prostate cancer
  • Conclusion
  • Chapter 13. Gynecologic imaging
  • Introduction
  • PET/MRI protocol
  • Uterine cervical cancer
  • Uterine endometrial cancer
  • Ovarian cancer
  • Vaginal cancer
  • Vulvar cancer
  • Summary
  • Chapter 14. Gastrointestinal imaging
  • Introduction
  • Acquisition protocols
  • Esophageal cancer
  • Gastric cancer
  • Colorectal cancer
  • Anal cancer
  • Inflammatory bowel disease
  • Chapter 15. Radiomics and artificial intelligence
  • Introduction
  • PET/MRI radiomics in brain tumors
  • PET/MRI radiomics in breast cancer
  • PET/MRI radiomics in pancreatic neuroendocrine tumors
  • PET/MRI radiomics in prostate cancer
  • Artificial intelligence for attenuation correction in PET/MR images
  • Conclusions
  • Index

Product details

  • No. of pages: 430
  • Language: English
  • Copyright: © Academic Press 2022
  • Published: September 7, 2022
  • Imprint: Academic Press
  • eBook ISBN: 9780323885386

About the Editor

Onofrio Catalano

Onofrio Antonio Catalano, MD, PhD, is Associated Professor of Radiology at Harvard Medical School. Dr. Catalano has been working on PET/MR since its first clinical introduction in 2012, at first building the PET/MR program in Naples, Italy, and then at the MGH/Harvard, in Boston, as medical director. He has read thousands of PET/MR scans and is one of the world most prolific researchers on the field of PET/MR. Among several achievements, Dr. Catalano has been the first to demonstrate the utility of PET/MR in the clinical oncologic settings, and the first to show the capabilities of PET/MR in discriminating fibrotic from inflammatory stenoses in Crohn disease patients.

Affiliations and Expertise

Associate Professor, Harvard Medical School, Massachusetts General Hospital, USA

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