Table of Contents

The uses of biochemical data in clinical medicine. The acquisition of biochemical data. The interpretation of biochemical data. Sodium, water and potassium. Hydrogen ion homoeostasis, tissue oxygenation and their disorders. Calcium, phosphate and magnesium. The kidneys, renal function and renal failure. Proteinuria. Renal tubular disorders and renal stone disease. The clinical biochemistry of nutrition. Nutritional disorders and their management. The clinical biochemistry of the gastrointestinal tract. The assessment of hepatic function and investigation of jaundice. Acute and chronic liver disease. Diabetes mellitus: pathophysiology and biochemical background. The clinical management of diabetes mellitus. Hypoglycaemia. Hypothalamic, pituitary and adrenal disorders. Thyroid dysfunction. Hormonal aspects of non-endocrine disease. Abnormal sexual development. The clinical biochemistry of female reproductive function, including pregnancy, oral contraception and hormone replacement therapy. Reproductive function in the male. Inherited metabolic disease. Paediatric clinical biochemistry. Biochemical aspects of anaemia. The porthyrias and disorders of haem synthesis. The haemoglobulinopathies. Immunology for clinical biochemists. Metabolic bone disease. Biochemical aspects of articular disease. Muscle disease. Investigation of cerebrospinal fluid. Biochemical aspects of psychiatric disorders. Biochemical aspects of neurological disease. Biochemical aspects of mental retardation. Lipid metabolism, hyper- and hypo-lipidaemias. The clinical biochemistry of the cardiovascular system. Therapeutic drug monitoring. Poisoning. Metabolic effects of tumours. Tumour markers. Molecular clinical biochemistry. Free radicals.

Details

No. of pages:
944
Language:
English
Copyright:
© 2014
Published:
Imprint:
Churchill Livingstone
eBook ISBN:
9780702057182
eBook ISBN:
9780702054785
Print ISBN:
9780702051401

About the authors

Márta Lapsley

Affiliations and Expertise

Consultant Chemical Pathologist, Epsom and St. Helier University Hospitals NHS Trust, Epsom, Surrey, UK

Andrew Day

Affiliations and Expertise

Consultant in Clinical Biochemistry and Metabolic Medicine, University Hospitals Bristol NHS Foundation Trust, Bristol, UK

Ruth Ayling

Affiliations and Expertise

Consultant in Clinical Biochemistry, Derriford Hospital, Plymouth, UK