Chemical Projects Scale Up - 1st Edition - ISBN: 9780128136102

Chemical Projects Scale Up

1st Edition

How to go from Laboratory to Commercial

Authors: Joe Bonem
Paperback ISBN: 9780128136102
Imprint: Elsevier Science
Published Date: 1st June 2018
Page Count: 466
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Chemical Projects Scale-up: How to go from Laboratory to Commercial covers the chemical engineering steps for taking a laboratory development into the commercial world. It covers such areas as:

Problems associated with scale up
Equipment sizing considerations
Thermal characteristics associated with scale up
Safety areas to consider
Recycle considerations
Operability reviews
Economic viability

In addition to process design aspects of commercializing the laboratory development, consideration is given to utilization of a development in an existing plant. These subjects are covered in an easy to understand fashion and examples are provided

Key Features

  • Explains how heat removal for exothermic reactions can be scaled up
  • Outlines how a reactor can be sized from batch kinetic data
  • Discusses how the plant performance of a new catalyst can be evaluated
  • Outlines how the economics of a new product/process can be developed
  • Discusses how recycle often necessary in commercial plants can be evaluated


Chemists and chemical engineers in either undergraduate (senior level) or graduate level. Chemists or chemical engineers that for the first time in their careers are working on a project that is being commercialized. A check list for project managers that are concerned about the experience level of the organization that is charged with the responsibility of a new project start-up

Table of Contents

1. Potential Problems with Scaleup
2. Equipment Design Considerations
3. Developing Commercial Process Flow Sheets
4. Thermal Characteristics for Reactor Scaleup
5. Safety Considerations
6. Recycle Considerations
7. Supplier’s Equipment Scaleup
8. Sustainability
9. Project Evaluation
10. Emergency Technology Contingency
11. Other Uses of Study Design
12. Scaling Up to Larger Commercial Sizes
13. Defining and Mitigating Risk
14. Typical Case Studies
15. Epilogue Final Words and Acknowledgements


No. of pages:
© Elsevier Science 2018
Elsevier Science
Paperback ISBN:

About the Author

Joe Bonem

Mr. Bonem’s highly productive five-decade career has included over three decades in Polymers manufacturing and process development with Exxon Chemical as well as 20 years in consulting. He is available for consulting in his areas of expertise. These areas include all phases of chemical engineering including Technology Transfer and Assimilation, Process Development and Scaleup, Project Basis Development and Process Design, Plant Performance Improvements and Safety Assessment of New and Existing Technology. Mr. Bonem is experienced in the development and mentoring of young engineers, and has extensive experience in working in foreign countries and cultures. He also has experience serving as an expert witness.

Affiliations and Expertise

Owner, Process Engineering and Polymers Consulting