Cellular Transplantation - 1st Edition - ISBN: 9780123694157, 9780080469041

Cellular Transplantation

1st Edition

From Laboratory to Clinic

Editors: Craig Halberstadt Dwaine Emerich
Hardcover ISBN: 9780123694157
eBook ISBN: 9780080469041
Imprint: Academic Press
Published Date: 11th December 2006
Page Count: 696
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Description

A. BASIC BIOLOGY OF CELL THERAPY.

  1. Immunology of Cell and Tissue Transplantation.
  2. Current Immunosuppressive Drugs and Clinical Use.
  3. Stem and Precursor Cells for Transplant Therapy.
  4. Creating Animals for Cell Xenotransplantation.

B. CELL THERAPY FOR PERIPHERAL DISEASES AND RECONSTRUCTIVE APPLICATIONS.

  1. Islet Transplants for Diabetes: The Edmonton Protocol.
  2. Encapsulated Human Islet Allografts: Providing Safety with Efficacy.
  3. Strategies for Cell Replacement for Kidney Failure.
  4. Strategies for Extracorporeal Devices for Kidney Failure.
  5. Transplants for Hemophilia.
  6. Cell Therapy for Peripheral Diseases and Reconstructive Applications: Transplants for Lysosomal Storage Disease.
  7. Cellular Transplants for Liver Diseases.
  8. Stem Cell Transplantation for Autoimmune Diseases.
  9. Cardiac Cell Transplantation.
  10. Engineered Cylindrical Cartilage Transplantation as Tracheal Replacements.
  11. Muscle Cell Transplants.

C. CELL THERAPY FOR CNS DISEASES.

  1. Immunological Consideration in CNS Transplants.
  2. Neurotrophic Cell Transplants for Degenerative Diseases of the Eye.
  3. Transplants for Glioblastoma.
  4. NT2N Cell Transplantation and GDNF Treatment in Stroke: Linking Neurotrophic Factor Therapy and Neuroprotection.
  5. NGF Producing Cell Transplants for Alzheimer’s Disease.
  6. Transplants of CNTF-Producing Cells for the Treatment of Huntington’s Disease.
  7. Choroid Plexus Epithelial Cell Transplants for Repair of the Brain.
  8. Neural Transplantation in Huntington’s Disease.
  9. Neural Transplantation in Parkinson’s Disease.
  10. Transplants for Chronic Pain.
  11. Cell Grafting for Spinal Cord Injury Repair: Cell Replacement and Bridging Strategies.
  12. Human Embryonic Stem Cells, Dopaminergic Neurons, and Pathways for Developing a Parkinson's Disease Therapy.

D. FUTURE AVENUES OF CELL THERAPY.

  1. Concepts in Cell Therapy: From Cord Blood to Sertoli Cells.
  2. Immunologically Privileged Environments.
  3. Converging Cell Therapy with Biomaterials.
  4. Nanotechnology’s Impact on Cell Transplantation.
  5. Design and Implementation of a Cell Processing Facility.
  6. Developing Cell Therapy Products.

Key Features

  • Provides detailed description of clinical trials in cell transplantation
  • Review of current therapeutic approaches
  • Coverage of the broad range of diseases addressed by cell therapeutics
  • Discussion of stem cell biology and its role in transplantation

Readership

Researchers and clinicians in the field of cell transplantation, as well as students in cell biology interested in how the field relates to cell transplantation

Table of Contents

A. BASIC BIOLOGY OF CELL THERAPY.

  1. Immunology of Cell and Tissue Transplantation.
  2. Current Immunosuppressive Drugs and Clinical Use.
  3. Stem and Precursor Cells for Transplant Therapy.
  4. Creating Animals for Cell Xenotransplantation.

B. CELL THERAPY FOR PERIPHERAL DISEASES AND RECONSTRUCTIVE APPLICATIONS.

  1. Islet Transplants for Diabetes: The Edmonton Protocol.
  2. Encapsulated Human Islet Allografts: Providing Safety with Efficacy.
  3. Strategies for Cell Replacement for Kidney Failure.
  4. Strategies for Extracorporeal Devices for Kidney Failure.
  5. Transplants for Hemophilia.
  6. Cell Therapy for Peripheral Diseases and Reconstructive Applications: Transplants for Lysosomal Storage Disease.
  7. Cellular Transplants for Liver Diseases.
  8. Stem Cell Transplantation for Autoimmune Diseases.
  9. Cardiac Cell Transplantation.
  10. Engineered Cylindrical Cartilage Transplantation as Tracheal Replacements.
  11. Muscle Cell Transplants.

C. CELL THERAPY FOR CNS DISEASES.

  1. Immunological Consideration in CNS Transplants.
  2. Neurotrophic Cell Transplants for Degenerative Diseases of the Eye.
  3. Transplants for Glioblastoma.
  4. NT2N Cell Transplantation and GDNF Treatment in Stroke: Linking Neurotrophic Factor Therapy and Neuroprotection.
  5. NGF Producing Cell Transplants for Alzheimer’s Disease.
  6. Transplants of CNTF-Producing Cells for the Treatment of Huntington’s Disease.
  7. Choroid Plexus Epithelial Cell Transplants for Repair of the Brain.
  8. Neural Transplantation in Huntington’s Disease.
  9. Neural Transplantation in Parkinson’s Disease.
  10. Transplants for Chronic Pain.
  11. Cell Grafting for Spinal Cord Injury Repair: Cell Replacement and Bridging Strategies.
  12. Human Embryonic Stem Cells, Dopaminergic Neurons, and Pathways for Developing a Parkinson's Disease Therapy.

D. FUTURE AVENUES OF CELL THERAPY.

  1. Concepts in Cell Therapy: From Cord Blood to Sertoli Cells.
  2. Immunologically Privileged Environments.
  3. Converging Cell Therapy with Biomaterials.
  4. Nanotechnology’s Impact on Cell Transplantation.
  5. Design and Implementation of a Cell Processing Facility.
  6. Developing Cell Therapy Products.

Details

No. of pages:
696
Language:
English
Copyright:
© Academic Press 2007
Published:
Imprint:
Academic Press
eBook ISBN:
9780080469041
Hardcover ISBN:
9780123694157

About the Editor

Craig Halberstadt

Affiliations and Expertise

Carolinas Medical Center, Charlotte, North Carolina

Dwaine Emerich

Affiliations and Expertise

LCT Biopharma, Providence, Rhode Island, U.S.A.