Description

The genetic, molecular, and cellular mechanisms of neural development are essential for understanding evolution and disorders of neural systems. Recent advances in genetic, molecular, and cell biological methods have generated a massive increase in new information, but there is a paucity of comprehensive and up-to-date syntheses, references, and historical perspectives on this important subject. The Comprehensive Developmental Neuroscience series is designed to fill this gap, offering the most thorough coverage of this field on the market today and addressing all aspects of how the nervous system and its components develop. Particular attention is paid to the effects of abnormal development and on new psychiatric/neurological treatments being developed based on our increased understanding of developmental mechanisms. Each volume in the series consists of review style articles that average 15-20pp and feature numerous illustrations and full references. Volume 2 offers 56 high level articles devoted mainly to Formation of Axons and Dendrites, Migration, Synaptogenesis, Developmental Sequences in the Maturation of Intrinsic and Synapse Driven Patterns.

Key Features

  • Series offers 144 articles for 2904 full color pages addressing ways in which the nervous system and its components develop
  • Features leading experts in various subfields as Section Editors and article Authors
  • All articles peer reviewed by Section Editors to ensure accuracy, thoroughness, and scholarship
  • Volume 2 sections include coverage of mechanisms which regulate: the formation of axons and dendrites, cell migration, synapse formation and maintenance during development, and neural activity, from cell-intrinsic maturation to early correlated patterns of activity.

Readership

Neuroscience, developmental biology researchers, including stem cells, aging and diseases. Translational neuroscience researchers - many neurodegeneration diseases (Alzheimers!) have their roots in mechanisms studied in development, and many psychiatric diseases (Autism!) are consequences of developmental problems (Rubenstein is Prof Psychiatry)

Details

No. of pages:
1080
Language:
English
Copyright:
© 2013
Published:
Imprint:
Academic Press
Print ISBN:
9780123972668
Electronic ISBN:
9780123973474

Reviews

"This…second of a three volume series…is intended to summarize the current state of developmental neuroscience. There are four sections with Rubenstein and Rakic as chief editors and each section having a section editor in charge of peer reviewing the articles therein. Section I is an overview of neuron development…The second section is on neuron migration during brain development…Section III is on synaptogenesis…The fourth section demonstrates the ways that the ongoing synaptic activity of the brain and not simply genetics mediates brain development."--Reference & Research Book News, December 2013