Cellular and Molecular Renewal in the Mammalian Body - 1st Edition - ISBN: 9780121569402, 9781483271385

Cellular and Molecular Renewal in the Mammalian Body

1st Edition

Editors: Ivan L. Cameron Jack D. Thrasher
eBook ISBN: 9781483271385
Imprint: Academic Press
Published Date: 1st January 1971
Page Count: 432
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Cellular and Molecular Renewal in the Mammalian Body concerns the dynamic nature of body constituents at the molecular, organelle, and cellular level of structural organization. Each chapter of this book deals with cellular and molecular renewal, proliferation, and loss, focusing on the body's major macromolecular classes, such as DNA, RNA, proteins, lipids, and carbohydrates. Other topics discussed include the subcellular renewal, DNA stability, regulation of cell proliferation, and changes in mitotic rates. The intracellular sites of RNA synthesis, proteins of the nucleus, and epithelial-mesenchymal interactions are also elaborated. This text likewise covers the brown adipose tissue, histochemistry of polysaccharides, and calcification. This publication is beneficial to students and investigators intending to acquire knowledge of the dynamic nature of body constituents and its influence to the analysis and experimentation of normal, disease, and repair processes within the body.

Table of Contents

List of Contributors Preface

  1. Approaches to the Study of Molecular and Cellular Renewal I. Introduction II. Cell Populations and Renewal III. Subcellular Renewal References
  2. The Metabolic Stability of Nuclear DNA I. Introduction II. DNA Constancy III. DNA Stability IV. Conclusions References
  3. Cell Proliferation and Renewal in the Mammalian Body I. Introduction II. Cell Proliferation and Growth during the Embryonic and Postnatal Periods III. Methods Used to Visualize and to Measure Cell Proliferation and Cell Renewal IV. Classification of Cell Populations Based on Their Proliferative Behavior V. Regulation of Cell Proliferation References
  4. Cellular Content and Cellular Proliferation Changes in the Tissues and Organs of the Aging Mammal I. Introduction II. Changes in Numbers of Cells and Nerve Fibers III. Changes in Mitotic Rates IV. Changes in Mucosal Cells of the Intestine V. Discussion References
  5. RNA Molecules in Cells and Tissues, In Vivo and In Vitro I. Introduction II. Intracellular Sites of RNA Synthesis III. Nuclear Sites of RNA Synthesis IV. The Biosynthesis of RNA Molecules V. Nucleic Acids of Mitochondria VI. RNA Synthesis in Special Cell Systems VII. RNA Synthesis over the Cell Cycle References
  6. Turnover of Intracellular Proteins I. Introduction II. Proteins of the Nucleus III. Turnover of Proteins in Cytoplasmic Systems IV. Proteins and the Cell Cycle V. Protein Metabolism in Special Cell Systems References
  7. The Dynamics of Extracellular and Cell Surface Protein Interactions I. Introduction II. Epigenetic Controls Regulating Differentiation: The Problem III. Outer Cell Surface Properties and Their Role in the Formation of Metazoan Systems IV. Epithelial-Mesenchymal Interactions V. The Extracellula


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© Academic Press 1971
Academic Press
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About the Editor

Ivan L. Cameron

Jack D. Thrasher

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