Cellular and Molecular Renewal in the Mammalian Body

Cellular and Molecular Renewal in the Mammalian Body

1st Edition - January 1, 1971

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  • Editors: Ivan L. Cameron, Jack D. Thrasher
  • eBook ISBN: 9781483271385

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Cellular and Molecular Renewal in the Mammalian Body concerns the dynamic nature of body constituents at the molecular, organelle, and cellular level of structural organization. Each chapter of this book deals with cellular and molecular renewal, proliferation, and loss, focusing on the body's major macromolecular classes, such as DNA, RNA, proteins, lipids, and carbohydrates. Other topics discussed include the subcellular renewal, DNA stability, regulation of cell proliferation, and changes in mitotic rates. The intracellular sites of RNA synthesis, proteins of the nucleus, and epithelial-mesenchymal interactions are also elaborated. This text likewise covers the brown adipose tissue, histochemistry of polysaccharides, and calcification. This publication is beneficial to students and investigators intending to acquire knowledge of the dynamic nature of body constituents and its influence to the analysis and experimentation of normal, disease, and repair processes within the body.

Table of Contents

  • List of Contributors


    1. Approaches to the Study of Molecular and Cellular Renewal

    I. Introduction

    II. Cell Populations and Renewal

    III. Subcellular Renewal


    2. The Metabolic Stability of Nuclear DNA

    I. Introduction

    II. DNA Constancy

    III. DNA Stability

    IV. Conclusions


    3. Cell Proliferation and Renewal in the Mammalian Body

    I. Introduction

    II. Cell Proliferation and Growth during the Embryonic and Postnatal Periods

    III. Methods Used to Visualize and to Measure Cell Proliferation and Cell Renewal

    IV. Classification of Cell Populations Based on Their Proliferative Behavior

    V. Regulation of Cell Proliferation


    4. Cellular Content and Cellular Proliferation Changes in the Tissues and Organs of the Aging Mammal

    I. Introduction

    II. Changes in Numbers of Cells and Nerve Fibers

    III. Changes in Mitotic Rates

    IV. Changes in Mucosal Cells of the Intestine

    V. Discussion


    5. RNA Molecules in Cells and Tissues, In Vivo and In Vitro

    I. Introduction

    II. Intracellular Sites of RNA Synthesis

    III. Nuclear Sites of RNA Synthesis

    IV. The Biosynthesis of RNA Molecules

    V. Nucleic Acids of Mitochondria

    VI. RNA Synthesis in Special Cell Systems

    VII. RNA Synthesis over the Cell Cycle


    6. Turnover of Intracellular Proteins

    I. Introduction

    II. Proteins of the Nucleus

    III. Turnover of Proteins in Cytoplasmic Systems

    IV. Proteins and the Cell Cycle

    V. Protein Metabolism in Special Cell Systems


    7. The Dynamics of Extracellular and Cell Surface Protein Interactions

    I. Introduction

    II. Epigenetic Controls Regulating Differentiation: The Problem

    III. Outer Cell Surface Properties and Their Role in the Formation of Metazoan Systems

    IV. Epithelial-Mesenchymal Interactions

    V. The Extracellular Matrix Influences upon Cellular Differentiation


    8. Synthesis, Localization, and Renewal of Lipids in Mammalian Tissues

    I. Introduction

    II. Fatty Acids and Triglycerides

    III. Cholesterol

    IV. Sphingolipids

    V. Phospholipids

    VI. Brown Adipose Tissue

    VII. Summary


    9. Localization, Identification, and Renewal of Carbohydrates in Tissues and Cells

    I. Introduction

    II. Histochemistry of Mucins

    III. Histochemistry of Polysaccharides


    10. Calcification



    Author Index

    Subject Index

Product details

  • No. of pages: 432
  • Language: English
  • Copyright: © Academic Press 1971
  • Published: January 1, 1971
  • Imprint: Academic Press
  • eBook ISBN: 9781483271385

About the Editors

Ivan L. Cameron

Jack D. Thrasher

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