Cell Mechanics - 1st Edition - ISBN: 9780123705006, 9780080548708

Cell Mechanics, Volume 83

1st Edition

Editors: Yu-Li Wang Dennis Discher
Hardcover ISBN: 9780123705006
eBook ISBN: 9780080548708
Imprint: Academic Press
Published Date: 5th July 2007
Page Count: 632
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Table of Contents

I. Basics Concept and Preparation of Culture Substrates for Cell Mechanical Studies. Basic Rheology for Biologists. Polyacrylamide Hydrogels for Cell Mechanics: Steps towards Optimization and Alternative Uses. Microscopic Methods for Measuring the Elasticity of Gel Substrates for Cell Culture: Microspheres, Microindenters, and Atomic Force Microscopy.
Surface Patterning. Molecular Engineering of Cellular Environments: Cell Adhesion to Nano-Digital Surfaces.

II. Subcellular Mechanical Properties and Activities. Probing Cellular Mechanical Responses to Stimuli Using Ballistic Intracellular Nanorheology. Multiple Particle Tracking and Two-Point Microrheology in Cells. Imaging Stress Propagation in the Cytoplasm of a Living Cell. Probing Intracellular Force Distributions by High-Resolution Live Cell Imaging and Inverse Dynamics. Analysis of Microtubule Curvature. Nuclear Mechanics and Methods.

III. Cellular and Embryonic Mechanical Properties and Activities.

The Use of Gelatin Substrates for Traction Force Microscopy in Rapidly Moving Cells. Microfabricated Silicone Elastomeric Post Arrays for Measuring Traction Forces of Adherent Cells. Cell Adhesion Strengthening: Measurement and Analysis. Studying the Mechanics of Cellular Processes by Atomic Force Microscopy. Using Force to Probe Single-Molecule Receptor-Cytoskeletal Anchoring beneath the Surface of a Living Cell. High Throughput Rheological Measurements with an Optical Stretcher. Measuring Mechanical Properties of Embryos and Embryonic Tissues.

IV. Mechanical Stimuli to Cells. Tools to Study Cell Mechanics and Mechanotransduction. Magnetic Tweezers in Cell Biology. Optical Neuronal Guidance. Microtissue Elasticity: Measurements by Atomic Force Microscopy and Its Influence on Cell Differentiation.
Demystifying the effects of a three-dimensional microenvironment in tissue morphogenesis.


Description

I. Basics Concept and Preparation of Culture Substrates for Cell Mechanical Studies. Basic Rheology for Biologists. Polyacrylamide Hydrogels for Cell Mechanics: Steps towards Optimization and Alternative Uses. Microscopic Methods for Measuring the Elasticity of Gel Substrates for Cell Culture: Microspheres, Microindenters, and Atomic Force Microscopy.
Surface Patterning. Molecular Engineering of Cellular Environments: Cell Adhesion to Nano-Digital Surfaces.

II. Subcellular Mechanical Properties and Activities. Probing Cellular Mechanical Responses to Stimuli Using Ballistic Intracellular Nanorheology. Multiple Particle Tracking and Two-Point Microrheology in Cells. Imaging Stress Propagation in the Cytoplasm of a Living Cell. Probing Intracellular Force Distributions by High-Resolution Live Cell Imaging and Inverse Dynamics. Analysis of Microtubule Curvature. Nuclear Mechanics and Methods.

III. Cellular and Embryonic Mechanical Properties and Activities.

The Use of Gelatin Substrates for Traction Force Microscopy in Rapidly Moving Cells. Microfabricated Silicone Elastomeric Post Arrays for Measuring Traction Forces of Adherent Cells. Cell Adhesion Strengthening: Measurement and Analysis. Studying the Mechanics of Cellular Processes by Atomic Force Microscopy. Using Force to Probe Single-Molecule Receptor-Cytoskeletal Anchoring beneath the Surface of a Living Cell. High Throughput Rheological Measurements with an Optical Stretcher. Measuring Mechanical Properties of Embryos and Embryonic Tissues.

IV. Mechanical Stimuli to Cells. Tools to Study Cell Mechanics and Mechanotransduction. Magnetic Tweezers in Cell Biology. Optical Neuronal Guidance. Microtissue Elasticity: Measurements by Atomic Force Microscopy and Its Influence on Cell Differentiation.
Demystifying the effects of a three-dimensional microenvironment in tissue morphogenesis.

Key Features

  • Presents a distinctive emphasis on matrix mechanics and their interplay with cell functions
  • Includes highly significant topics relevant to basic and translational research, as well as tissue engineering
  • Emphasizes mechanical input and output of cells

Readership

Cell biologists, neurobiologists, tissue engineers, translational biologists in fields of cancer, cardiovascular medicine, orthopedic medicine. Physicists and mechanical engineers interested in entering biomedical research.


Details

No. of pages:
632
Language:
English
Copyright:
© Academic Press 2007
Published:
Imprint:
Academic Press
eBook ISBN:
9780080548708
Hardcover ISBN:
9780123705006

About the Editors

Yu-Li Wang Editor

Affiliations and Expertise

University of Massachusetts Medical School, Worcester, MA, USA

Dennis Discher Editor

Affiliations and Expertise

University of Pennsylvania, Philadelphia, PA, USA