Cell Interactions in Differentiation

Cell Interactions in Differentiation

1st Edition - January 1, 1977

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  • Editor: Marketta Karkinen-Jaaskelainen
  • eBook ISBN: 9780323150552

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Cell Interactions in Differentiation is a collection of papers presented at the Sixth Sigrid Jusélius Foundation Symposium held in Helsinki, Finland, in August 1976. Contributors discuss cell interactions during differentiation, particularly referring to the problem of embryonic induction. They also consider how a cell becomes adjusted to the synchronized development of an entire multicellular organism, so as to express its genetic information at a strictly controlled time and place. This volume is organized into five sections encompassing 30 chapters and begins with an overview of embryonic cells and their two fundamental properties. Cells are not necessarily predetermined and can be experimentally diverted from their normal developmental pathway, and those within an embryonic organism require extrinsic messages to express their developmental capacities. The next chapters focus on early determinative events in embryogenesis, touching on topics such as the genetic aspects of cell type determination, interactions between embryonic cells during the early development of the mouse, and the differentiation of teratocarcinoma stem cells in vitro. The reader is then introduced to positional information and morphogenetic signals; the biological ""specificity"" of morphogenetic tissue interactions; and the molecular mechanisms underlying cell contact interactions. The remaining chapters explore some of the most important conceptual and methodological approaches to the problems of cell-cell recognition and the integration of cells into multicellular systems. This book will be of interest to scientists and investigators in developmental biology and related fields.

Table of Contents

  • List of Participants


    Opening Remarks


    I. Early Determinative Events in Embryogenesis

    Early Determinative Events in Embryogenesis: An Introduction

    Analysis of a Cytoplasmic Determinant in a Insect Egg

    Genetics of Cell Type Determination

    Interactions between Embryonic Cells during the Early Development of the Mouse

    The Differentiation of Teratocarcinoma Stem Cells in vitro: Parallels to Normal Embryogenesis

    II. Positional Information and Morphogenese Signals

    Positional Information and Morphogenetic Signals: An Introduction

    Compartments in the Development of Drosophila: A Progress Report

    Positional Signalling and Nerve Cell Specificity

    Organizing Principles for Anatomical Patterns and for Selective Nerve Connections in the Developing Amphibian Brain

    Regulation of Proximo-distal Pattern Formation in the Developing Limb

    III. Morphogenetic Tissue Interactions

    Embryonic Induction: An Historical Note

    Morphogenetic Tissue Interactions: An Introduction

    Tissue Interactions in Amniote Skin Development

    The Differentiation of the Ganglioblasts of the Autonomic Nervous System Studied in Chimeric Avian Embryos

    Tissue Interactions in Tooth Development in vitro

    Epigenetic Regulation of Enamel Protein Synthesis during Epithelial- Mesenchymal Interactions

    Studies on Primary Embryonic Induction

    Kidney Tubule Induction: Physical and Chemical Interference

    Stimulation of Chondrogenic Differentiation with Extracellular Matrix Components: A n Analysis using Scanning Electron Microscopy

    IV. Molecular Mechanisms of Cell Contact Interactions

    Molecular Mechanisms of Cell Contact Interactions: An Introduction

    Some Biophysical Aspects of Cell Contact, Detachment and Movement

    Some Chemical Bases for Biological Specificity as Exemplified by Hapten-Antibody Interactions

    Interactions of Fibronectin, a Cell-Type Specific Surface-Associated Glycoprotein

    Gap Junctions and Cell Contacts

    The Molecular Basis of the Mesenchymal-Epithelial Interactions in Pancreatic Development

    V. Cell Recognition

    Cell Recognition: An Introduction

    Mechanisms of Cell-Cell Recognition: Some Comparisons between Lower Organisms and Vertebrates

    Periodic Cyclic-AMP Signals and Membrane Differentiation in Dictyostelium

    Developmental Interactions Studied with Experimental Teratomas derived from Mutants at the T/t Locus in the Mouse

    Self-recognition Phenomenon in Acquired Immunity

    Subject Index

Product details

  • No. of pages: 432
  • Language: English
  • Copyright: © Academic Press 1977
  • Published: January 1, 1977
  • Imprint: Academic Press
  • eBook ISBN: 9780323150552

About the Editor

Marketta Karkinen-Jaaskelainen

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