Cardiovascular disease remains a major cause of death and disability in developed countries and, increasingly so, in the developing world. Presented in this volume of Advances in Pharmacology are some of the most promising possibilities for treating large numbers of individuals afflicted with these conditions

Key Features

This volume contains up-to-date reviews of the most important emerging cardiovascular therapies written by world leaders in the field.


Pharmacologists, immunologists, and biochemists.

Table of Contents

  1. The Cardiovascular Physiology and Pharmacology of Endothelin-1
  2. Eric Thorin and Martine Clozel

  3. Vascular Pharmacology of Epoxyeicosarienoic Acids
  4. Sandra L. Pfister, Kathryn M. Gauthier, and William B. Campbell

  5. Prostaglandins in Action: Indispensable Roles of Cyclooxygenase-1 and 2 in Endothelium-dependent Contractions
  6. Siu Ling Wong, Wing Tak Wong, Xiao Yu Tian, Chi-Wai Lau, and Yu Huang

  7. TP Receptors and Oxidative Stress: Hand in Hand from Endothelial Dysfunction to Atherosclerosis
  8. Michel Félétou, Richard A. Cohen, Paul M. Vanhoutte and Tony J. Verbeuren

  9. Regulation of Endothelial Cell Tetrahydrobiopterin: Pathophysiological and Therapeutic Implications
  10. Li Li, Wei Chen, and David G. Harrison

  11. Polyphenol-Induced Endothelium-Dependent Relaxations: Role of NO and EDHF
  12. Valerie B. Schini-Kerth, Cyril Auger, Nelly Etienne-Selloum, and Thierry Chataigneau


  13. Organic Nitrates and Nitrate Tolerance – State of the Art and Future Developments
  14. Andreas Daiber and Tommaso Gori

  15. Vascular Actions of Adipokines: Molecular Mechanism and Therapeutic Intervention
  16. Aimin Xu, Yu Wang, Karen Lam, and Paul M. Vanhoutte

  17. Cardiovascular Effects of Erythropoietin: An Update

Anantha Santhanam, Livius d’Uscio, and Zvonimir Katusic


No. of pages:
© 2010
Academic Press
eBook ISBN:
Print ISBN:

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