Cardiac Regeneration and Repair

1st Edition

Biomaterials and Tissue Engineering

Editors: Ren-Ke Li Richard D. Weisel
Hardcover ISBN: 9780857096593
eBook ISBN: 9780857096715
Imprint: Woodhead Publishing
Published Date: 22nd January 2014
Page Count: 486
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Table of Contents

  • Contributor contact details
  • Woodhead Publishing Series in Biomaterials
  • Foreword
  • Introduction
  • Part I: Biomaterials for cardiac regeneration and repair
    • Chapter 1: Nanotechnology and nanomaterials for cardiac repair
      • Abstract:
      • 1.1 Introduction
      • 1.2 Electrospinning nanofibrous scaffolds
      • 1.3 Conductive nanomaterial for myocardial infarction (MI)
      • 1.4 Nanomedicine
      • 1.5 Future trends
    • Chapter 2: Hydrogels for cardiac repair
      • Abstract:
      • 2.1 Introduction
      • 2.2 Hydrogels
      • 2.3 Injectable hydrogels alone for cardiac repair
      • 2.4 Hydrogels as a platform for co-delivery
      • 2.5 Delivery strategies of hydrogels
      • 2.6 Future trends
      • 2.7 Sources of further information and advice
    • Chapter 3: Injectable biomaterials for cardiac regeneration and repair
      • Abstract:
      • 3.1 Introduction
      • 3.2 Design criteria for biomaterials in cardiac tissue engineering
      • 3.3 Injectable biomaterials
      • 3.4 Bioactive molecules used in cardiac tissue engineering
      • 3.5 Hydrogels to promote endogenous cardiac regeneration and repair
      • 3.6 Hydrogels for the delivery of cells for cardiac regeneration
      • 3.7 Hydrogels for the artificial maintenance of ventricle geometry and repair
      • 3.8 Future trends
    • Chapter 4: Biomaterials for enhancing endothelial progenitor cell (EPC) therapy for cardiac regeneration
      • Abstract:
      • 4.1 Introduction
      • 4.2 Endothelial progenitor cells (EPCs)
      • 4.3 Enhancing EPC therapy
      • 4.4 Future trends
      • 4.5 Conclusion
    • Chapter 5: Endothelial progenitor cell (EPC)-seeded intravascular stents
      • Abstract:
      • 5.1 Intravascular stents
      • 5.2 Endothelial progenitor cells (EPCs)
      • 5.3 EPC-seeded intravascular stents
      • 5.4

Description

Cardiac Regeneration and Repair, Volume Two reviews the use of biomaterials, alone or combined with cell therapy, in providing tissue-engineered constructs to repair the injured heart and prevent or reverse heart failure.

Part one explores the variety of biomaterials available for cardiac repair, including nanomaterials and hydrogels. Further chapters explore the use of biomaterials to enhance stem cell therapy for restoring ventricular function and generating stem cell-modified intravascular stents. Part two focuses on tissue engineering for cardiac repair, including chapters on decellularized biologic scaffolds, synthetic scaffolds, cell sheet engineering, maturation of functional cardiac tissue patches, vascularized engineered tissues for in vivo and in vitro applications, and clinical considerations for cardiac tissue engineering. Finally, part three explores vascular remodeling, including chapters highlighting aortic extracellular matrix remodeling, cell-biomaterial interactions for blood vessel formation, and stem cells for tissue-engineered blood vessels.

Cardiac Regeneration and Repair, Volume Two is complemented by an initial volume covering pathology and therapies. Together, the two volumes of Cardiac Regeneration and Repair provide a comprehensive resource for clinicians, scientists, or academicians fascinated with cardiac regeneration, including those interested in cell therapy, tissue engineering, or biomaterials.

Key Features

  • Surveys the variety of biomaterials available for cardiac repair, including nanomaterials and hydrogels.
  • Focuses on tissue engineering for cardiac repair including clinical considerations for cardiac tissue engineering
  • Explores vascular remodeling, highlighting aortic extracellular matrix remodeling, cell-biomaterial interactions for blood vessel formation, and stem cells for tissue-engineered blood vessels

Readership

Scientists and academic researchers in the areas of cardiac regeneration and repair, tissue engineering, cell therapies, and biomaterials; Cardiovascular doctors, cardiac surgeons, and cardiologists; Stem cell researchers


Details

No. of pages:
486
Language:
English
Copyright:
© Woodhead Publishing 2014
Published:
Imprint:
Woodhead Publishing
eBook ISBN:
9780857096715
Hardcover ISBN:
9780857096593
Paperback ISBN:
9780081015605

Reviews

Cardiac Regeneration and Repair, Volume Two reviews the use of biomaterials, alone or combined with cell therapy, in providing tissue-engineered constructs to repair the injured heart and prevent or reverse heart failure.

Part one explores the variety of biomaterials available for cardiac repair, including nanomaterials and hydrogels. Further chapters explore the use of biomaterials to enhance stem cell therapy for restoring ventricular function and generating stem cell-modified intravascular stents. Part two focuses on tissue engineering for cardiac repair, including chapters on decellularized biologic scaffolds, synthetic scaffolds, cell sheet engineering, maturation of functional cardiac tissue patches, vascularized engineered tissues for in vivo and in vitro applications, and clinical considerations for cardiac tissue engineering. Finally, part three explores vascular remodeling, including chapters highlighting aortic extracellular matrix remodeling, cell-biomaterial interactions for blood vessel formation, and stem cells for tissue-engineered blood vessels.

Cardiac Regeneration and Repair, Volume Two is complemented by an initial volume covering pathology and therapies. Together, the two volumes of Cardiac Regeneration and Repair provide a comprehensive resource for clinicians, scientists, or academicians fascinated with cardiac regeneration, including those interested in cell therapy, tissue engineering, or biomaterials.


About the Editors

Ren-Ke Li Editor

Ren-Ke Li, University of Toronto, Canada.

Richard D. Weisel Editor

Richard D. Weisel, University of Toronto, Canada.

Affiliations and Expertise

University of Toronto, Canada