Cancer Theranostics

1st Edition

Editors: Xiaoyuan Chen Stephen Wong
Hardcover ISBN: 9780124077225
eBook ISBN: 9780124078840
Imprint: Academic Press
Published Date: 20th March 2014
Page Count: 544
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Description

Aiding researchers seeking to eliminate multi-step procedures, reduce delays in treatment and ease patient care, Cancer Theranostics reviews, assesses, and makes pertinent clinical recommendations on the integration of comprehensive in vitro diagnostics, in vivo molecular imaging, and individualized treatments towards the personalization of cancer treatment.

Cancer Theranostics describes the identification of novel biomarkers to advance molecular diagnostics of cancer. The book encompasses new molecular imaging probes and techniques for early detection of cancer, and describes molecular imaging-guided cancer therapy. Discussion also includes nanoplatforms incorporating both cancer imaging and therapeutic components, as well as clinical translation and future perspectives.

Key Features

  • Supports elimination of multi-step approaches and reduces delays in treatments through combinatorial diagnosis and therapy
  • Fully assesses cancer theranostics across the emergent field, with discussion of biomarkers, molecular imaging, imaging guided therapy, nanotechnology, and personalized medicine
  • Content bridges laboratory, clinic, and biotechnology industries to advance biomedical science and improve patient management

Readership

Industry and academia working on drug discovery/development, pharmacology, personalized medicine, nanomedicine, medical imaging, imaging guided therapy, biomarkers, molecular pathology, proteomics, genomics, microarray chips, molecular biology.

Table of Contents

  • Preface
  • Acknowledgments
  • About the Editors
  • List of Contributors
  • Part I: In Vitro Diagnostics

    • Chapter 1. Cancer Theranostics: An Introduction

      • Cancer Theranostics: A Definition
      • Theranostic Cancer Biomarkers
      • Molecular Imaging in Cancer Theranostics
      • Imaging-Guided Cancer Therapy
      • Theranostic Platforms
      • Challenges and Future Perspectives
      • References
    • Chapter 2. Genomics-Based Cancer Theranostics

      • Introduction
      • Next Generation Sequencing Technology for Genomics-Based Cancer Theranostics
      • Genomics Landscapes in Common Forms of Human Cancers
      • Functions of Key Signaling Pathways in Cancer
      • Integration of Genomic Screening for Cancer Theranostics
      • Acknowledgments
      • Glossary
      • Abbreviations
      • References
    • Chapter 3. Proteomics-Based Theranostics

      • Introduction
      • Mass Spectrometry Techniques Used for Proteomics Biomarker Discovery
      • Bioinformatics Analysis Pipeline for Proteomics Biomarker Discovery
      • Challenges in Proteomics Biomarker Discovery
      • Existing Single Biomarkers
      • Knowledge-Integrated Network Biomarker Discovery
      • Clinical Validation of Proteomics Biomarkers
      • Glossary
      • Abbreviations
      • References
  • Part II: Molecular Imaging

    • Chapter 4. Radionuclide Imaging of Cancer Therapy

      • Bone Scintigraphy
      • Thyroid Radioiodine Scintigraphy
      • Nonspecific Single-Photon Radiotracers
      • Positron Emission Tomography
      • Conclusion
      • References
    • Chapter 5. Near-Infrared Fluorescence Imaging Probes for Cancer Diagnosis and Treatment

      • Introduction
      • Antibody-Based NIR Probes
      • Peptide-Based NIR Probes
      • Aptamer-Based NIR Probes
      • Polymer-Based NIR Probes
      • Lipid-Ba

Details

No. of pages:
544
Language:
English
Copyright:
© Academic Press 2014
Published:
Imprint:
Academic Press
eBook ISBN:
9780124078840
Hardcover ISBN:
9780124077225
Paperback ISBN:
9780128102992

About the Editor

Xiaoyuan Chen

Xiaoyuan (Shawn) Chen, PhD, is a Senior Investigator and Chief of the Laboratory of Molecular Imaging and Nanomedicine (LOMIN) at the National Institute of Biomedical Imaging and Bioengineering (NIBIB), National Institutes of Health (NIH). He is also founding editor of journal Theranostics. He holds a PhD in Chemistry from the University of Idaho.

Affiliations and Expertise

Laboratory of Molecular Imaging and Nanomedicine, National Institute of Biomedical Imaging and Bioengineering, National Institutes of Health

Stephen Wong

Stephen T.C. Wong, PhD (Computer Science), PE (Electrical Engineering), is John S. Dunn Distinguished Endowed Chair of Biomedical Engineering at Houston Methodist Hospital, the Founding Chair of Department of Systems Medicine and Bioengineering at Houston Methodist Research Institute, and a Professor of Radiology, Neurosciences, Pathology, and Laboratory Medicine at Weill Cornell Medical College.

Affiliations and Expertise

Methodist Hospital Research Institute

Awards

BMA Medical Book Awards 2015: Highly Commended, Oncology, British Medical Association

Reviews

"...reviews, assesses, and makes pertinent clinical recommendations on the integration of comprehensive in vitro diagnostics, in vivo molecular imaging, and individualized treatments…"--Anticancer Research, January 2015