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Bone Remodeling Process - 1st Edition - ISBN: 9780323884679

Bone Remodeling Process

1st Edition

Mechanics, Biology, and Numerical Modeling

Authors: Rabeb Kahla Abdelwahed Barkaoui
Paperback ISBN: 9780323884679
Imprint: Academic Press
Published Date: 1st August 2021
Page Count: 200
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Bone Remodeling Process: Mechanics, Biology, and Numerical Modeling provides a literature review. The first part of the book discusses bones in a normal physiological condition, bringing together the involved actors and factors reported over the past two decades, and the second discusses pathological conditions, highlighting the attack vectors of each bone disease. The third part is devoted to the mathematical descriptions of bone remodeling, formulated to develop models able to provide information that is not amenable to direct measurement, while the last part focuses on models using the finite element method in investigating bone biomechanics.

This book creates an overall image of the complex communication network established between the diverse remodeling actors, based on overwhelming control evidence revealed over recent years, as well as visualizes the remodeling defects and possible treatments in each case. It also regroups the models allowing readers to analyze and assess bone mechanical and biological properties. This book details the cellular mechanisms allowing the bone to adapt its microarchitecture to the requirements of the human body, which is the main issue in bone biology and presents the evolution of mathematical modeling used in a bone computer simulation.

Key Features

  • Each chapter covers a core topic in bone biomechanics 
  • Provides a multidisciplinary view that effectively links orthopaedics, cellular biology, mechanics, and computer simulation 
  • Draws an overall image about bone biology and cell interactions, for identifying cell populations that are crucial for the remodeling process  


Mechanical and biomechanical engineers working on orthopaedics and regenerative medicine. Computational engineers working on finite element method in bone biomechanics and mechanobiology. Researchers in the field of bone biomechanics and mechanobiology. Researchers working on bone biology and quality assessment. Clinicians and industrial pharmacists enhancing and developing drugs and therapeutic procedures. PhD students working on bone biology and/or bone biomechanics

Table of Contents

1. Bone multiscale mechanics
2. Bone remodeling biology
3. Bone diseases and associated therapeutic solutions
4. Bone remodeling mathematical models
5. Bone and bone remodeling finite element modeling
6. Bone remodeling: Analysis, discussion and perspectives


No. of pages:
© Academic Press 2021
1st August 2021
Academic Press
Paperback ISBN:

About the Authors

Rabeb Kahla

Rabeb BEN KAHLA is a Mechanical Engineering PhD student at the National Engineering School of Tunis, Tunisia. She conducts research at LASMAP (Research Laboratory of Systems and Applied Mechanics) of Tunisia Polytechnic School. Currently assistant teacher at Ecole d'Ingénieurs Généraliste du Numérique (Efrei PARIS), France, she is the author of the book “Finite element method and medical imaging techniques in bone biomechanics” (Wiley ISBN: 978-1-786-30518-3) and three publications in well-known journals in the field of biomechanics (Journal of the Mechanical Behavior of Biomedical Materials, Biomechanics and Modeling in Mechanobiology , Journal of Mechanics in Medicine and Biology).

Affiliations and Expertise

Researcher, LASMAP (Research Laboratory of Systems and Applied Mechanics), Tunisia Polytechnic School, Tunisia

Abdelwahed Barkaoui

Abdelwahed BARKAOUI is an associate professor of Mechanical Engineering at International University of Rabat. Currently assistant director of LERMA laboratory and head of mechanical discipline at renewable energy school, his research mainly targets problems in biomechanics, mechanobiology and biomedical engineering. He was member of editorial board of several international scientific journals and reviewer for several international journals known in the field of biomechanics and mechanical engineering. Besides, he is author of two books: “Finite element method and medical imaging techniques in bone biomechanics” (Wiley ISBN: 978-1-786-30518-3), and FEM Analysis of the Human Knee Joint A Review (Springer, ISBN:9783319741574), in addition to more than 30 journal publications.

Affiliations and Expertise

Assistant Director, Renewable Energies and Advanced Materials Laboratory, International University of Rabat; Associate Professor, Mechanical Engineering, International University of Rabat, Morocco

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