1st Edition - April 30, 2021

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  • Author: C. Raymond Lake
  • Paperback ISBN: 9780128192566
  • eBook ISBN: 9780128192573

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It is estimated that as many as fifty percent of patients initially diagnosed with major Unipolar depression (UP, MDD) will subsequently incur a manic episode or discover a past subtle episode and will have had Bipolar depression rather than MDD. The average Bipolar individual suffers with episodic symptoms for ten years before receiving an accurate diagnosis. As many as 16 million individuals in the United States will have a Bipolar episode in their lives, diagnosed or not. With the recognition of these growing numbers of patients with a Bipolar Disorder, it is imperative that patients are diagnosed and treated earlier, accurately and efficiently.   Untreated Bipolar usually gets worse. Bipolar aims to improve recognition, acceptance, and compliance. Dr. C. Raymond Lake applies two different approaches , comprehensive research and case studies, to the understanding of Bipolar Disorders,  presenting basic, selected Bipolar data including history, diagnostic criteria, definitions of terms, and classifications, as well as management and treatment strategies to help the reader fully comprehend the disorder. In addition, case studies provide the reader with real-life examples to help increase recognition of various Bipolar presentations beyond the stark black-and-white diagnostic criteria of the DSM and ICD.

Key Features

  • Explains differences between Bipolar and Unipolar Disorders
  • Provides crucial information on psychotherapy and mood-stabilizing medications as treatment options
  • Demonstrates diagnostic interviewing for physicians and patients
  • Discusses differential diagnoses for Bipolar
  • Includes difficult-to-diagnose case studies of various presentations in Bipolar


Researchers and graduate students in psychology studying bipolar disorder. Psychologists and psychiatrists treating patients with bipolar disorder

Table of Contents

  • 1. Introduction and Chapter Summaries
    2. The Spectrum of Mood Disorders: Bipolar I, Bipolar II, and Unipolar
    3. A 2,000-year History of Bipolar
    4. Bipolar Is a Neurogenetic Disease of the Brain, Not a Psychological Condition
    5. The Disaster of a Missed Diagnosis; How It Happens
    6. The Introduction of "Schizophrenia" Deprived Bipolar Patients of Proper Care; a History
    7. The Diagnosis of Bipolar Recovers from the 1970s to the Present; the Continuum Concept Ends the Kraepelinian Dichotomy and "Schizophrenia"
    8. Psychotic Mood Disorders Are Disorders of Thought and Mood; A Damaged Brain Selective-Attention Filter Explains Psychotic Manic Thought
    9. Paranoid Delusions Explained by Manic Grandiosity and the Guilt of Depression; There Is No "Schizophrenia"
    10. The Differential Diagnoses for Bipolar
    11. Difficult-to-Diagnose Case Studies Demonstrating Wide Variations in Presentations
    12. Psychotic Perpetrators of Violence, Murder, and Mass Murder Are Bipolar
    13. The Initial Diagnostic Interview for Physicians and Patients
    14. Treatment of Bipolar: What to Expect; How to Manage the Chaos
    15. Conclusions and Future Considerations for Bipolar

Product details

  • No. of pages: 570
  • Language: English
  • Copyright: © Academic Press 2021
  • Published: April 30, 2021
  • Imprint: Academic Press
  • Paperback ISBN: 9780128192566
  • eBook ISBN: 9780128192573

About the Author

C. Raymond Lake

C. Raymond Lake
Dr. Lake graduated with BS and MS degrees in Zoology from Tulane University, New Orleans, LA, in 1965 and 1966. He graduated from Duke University in Durham, NC, School of Medicine with an MD and from the Duke Graduate School (Department of Physiology and Pharmacology) with a Ph.D., in 1971 and 1972. He studied at Oxford University and at St. Bartholomew’s Hospital, London. His residency in Psychiatry was completed at Duke and at the National Institute of Mental Health (NIMH), Bethesda, MD. At Duke he was taught and continues to practice individual, couples and group psychotherapy. At the NIMH, he was privileged to collaborate with and learn about bipolar from Drs. Fred Goodwin, Bob Post, Dennis Murphy, Julie Axelrod and Irv Kopin. He remained in the Laboratory of Clinical Sciences as a research associate, then staff psychiatrist until 1980 when he moved “across the Pike” to take a professorship of Psychiatry and Pharmacology at the then new Uniformed Services University of the Health Sciences (USUHS), School of Medicine, Bethesda, MD. He secured two NIH RO1’s, continuing his research on the regulation of the sympathetic nervous system in health and in patients with neuropsychiatric and cardiovascular disorders. He taught medical students and residents in Psychiatry while following patients in his office and clinics. In 1993 he accepted the Chairmanship of Psychiatry at the University of Kansas, School of Medicine, Kansas City, Kansas, and remained Chair for three years after which he continued as Professor on the full-time faculty until his recent partial retirement. As Professor Emeritus he continues to publish about Mood Disorders and to follow his long-term Bipolar patients. Dr. Lake has over 250 journal publications including in Science, Nature, NEJM, AJP and AGP. His book titled Schizophrenia is a Misdiagnosis was published by Springer in 2012. He has achieved distinguished life-fellowship status in the American Psychiatric Association and the American College of Neuropsychopharmacology.

Affiliations and Expertise

Professor Emeritus, Department of Psychiatry and Behavioral Sciences, University of Kansas Health Systems, Kansas City, KS, USA

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