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Biosensors and Bioelectronics - 1st Edition - ISBN: 9780128031001, 9780128031018

Biosensors and Bioelectronics

1st Edition

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Authors: Chandran Karunakaran Kalpana Bhargava Robson Benjamin
Hardcover ISBN: 9780128031001
eBook ISBN: 9780128031018
Imprint: Elsevier
Published Date: 29th July 2015
Page Count: 344
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Biosensors and Bioelectronics presents the rapidly evolving methodologies that are relevant to biosensors and bioelectronics fabrication and characterization. The book provides a comprehensive understanding of biosensor functionality, and is an interdisciplinary reference that includes a range of interwoven contributing subjects, including electrochemistry, nanoparticles, and conducting polymers.

Authored by a team of bioinstrumentation experts, this book serves as a blueprint for performing advanced fabrication and characterization of sensor systems—arming readers with an application-based reference that enriches the implementation of the most advanced technologies in the field.

Key Features

  • Features descriptions of functionalized nanocomposite materials and carbon fibre electrode-based biosensors for field and in vivo applications
  • Presents a range of interwoven contributing subjects, including electrochemistry, nanoparticles, and conducting polymers
  • Includes more than 70 figures and illustrations that enhance key concepts and aid in retention
  • Ideal reference for those studying bioreceptors, transducers, bioinstrumentation, nanomaterials, immunosensors, nanotubes, nanoparticles, and electrostatic interactions
  • Authored by a collaborative team of scientists with more than 50 years of experienced in field research and instruction combined


Chemical Engineers (primarily those in the R&D sector), Electronics Engineers, and Materials Scientists. Secondary audience includes students at the upper undergraduate and graduate level taking related coursework

Table of Contents

    <li>Preface</li> <li>Chapter 1. Introduction to Biosensors<ul><li>1.1. Introduction</li><li>1.2. Basic principle of a biosensor</li><li>1.3. Components of a biosensor</li><li>1.4. Molecular recognition</li><li>1.5. Classification of biosensors based on transducers</li><li>1.6. Piezoelectric biosensors</li><li>1.7. Magnetoelastic biosensors</li><li>1.8. Field effect transistor-based biosensor</li><li>1.9. Calorimetric biosensor</li><li>1.10. Noninvasive biosensors</li><li>1.11. Electrochemical biosensors</li><li>1.12. Various electrochemical techniques</li><li>1.13. Electroanalytical characteristics of biosensors</li><li>1.14. Membranes used in biosensors for selectivity</li><li>1.15. Biosensor electrode fabrication techniques</li></ul></li> <li>Chapter 2. Nanocomposite Matrix Functionalization for Biosensors<ul><li>2.1. Introduction</li><li>2.2. Organic conducting polymers</li><li>2.3. Inorganic nanoparticles</li><li>2.4. Chitosan and Nafion</li><li>2.5. Immobilization strategies</li><li>2.6. Properties of immobilized enzymes</li><li>2.7. The biology of enzyme immobilization</li></ul></li> <li>Chapter 3. Enzymatic Biosensors<ul><li>3.1. Enzymatic biosensors</li><li>3.2. History of biosensors</li><li>3.3. Enzymatic and nonenzymatic biosensors for various diseases</li><li>3.4. Biomarkers for diagnosis of diseases</li><li>3.5. Glucose oxidase-based glucose biosensors for diabetes</li><li>3.6. Noninvasive glucose biosensor</li><li>3.7. Implantable glucose biosensors</li><li>3.8. Cholesterol biosensor</li><li>3.9. Oxidative stress biomarkers</li><li>3.10. Superoxide anion radical biosensor</li><li>3.11. Thiol biosensor</li><li>3.12. Nitric oxide biosensor</li><li>3.13. Nitrite biosensor</li><li>3.14. Nitrate reductase-based biosensor for nitrate</li><li>3.15. Apoptosis marker</li><li>3.16. Simultaneous determination of biomarkers</li><li>3.17. Bienzymatic biosensor</li><li>3.18. Enzyme inhibition-based biosensors</li><li>3.19. Enzyme mimetic (metalloporphyrin)-based biosensors</li><li>3.20. Screen-printed functionalized electrodes and advantages</li><li>3.21. Nanocomposite-enhanced electrochemical biosensors</li><li>3.22. Recent applications</li><li>3.23. Veterinary</li><li>3.24. Food and agriculture</li><li>3.25. Biomedical applications</li></ul></li> <li>Chapter 4. Immunosensors<ul><li>4.1. Introduction</li><li>4.2. Antibody as biorecognition element</li><li>4.3. Types of antibodies and antibody fragments</li><li>4.4. Types of immunosensors</li><li>4.5. Labeled and label-free immunosensors</li><li>4.6. Immunosensor applications</li><li>4.7. Future prospects</li></ul></li> <li>Chapter 5. Instrumentation<ul><li>5.1. Virtual instrumentation</li><li>5.2. Introduction to NI LabVIEW</li><li>5.3. Difference between LabVIEW and conventional languages</li><li>5.4. Front panel</li><li>5.5. Block diagram</li><li>5.6. Icon and connector panel</li><li>5.7. Controls palette</li><li>5.8. Function palette</li><li>5.9. Tools palette</li><li>5.10. Creating, editing, wiring, debugging, and saving VIs</li><li>5.11. SubVIs &#x2013; creating subVIs</li><li>5.12. Looping: for loop, while loop</li><li>5.13. Shift registers and sequence locals</li><li>5.14. Case and sequence structures</li><li>5.15. MyDAQ</li><li>5.16. Virtual electrochemical analyzer</li><li>5.17. Electronics of electrochemical biosensor</li></ul></li> <li>Index</li>


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© Elsevier 2016
29th July 2015
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About the Authors

Chandran Karunakaran

Chandran Karunakaran, PhD, is Associate Professor of Chemistry in the Biomedical Research Lab at VHNSN College, Tamilnadu, India. Dr. Karunakaran received his PhD in magnetic resonance and has worked in the National Biomedical EPR Centre and Free Radical Research Centre in Medical College of Wisconsin for the last 5 years as Postdoc, Research Scientist and Assistant Professor.

Affiliations and Expertise

Associate Professor of Chemistry, Biomedical Research Lab, VHNSN College, Tamilnadu, India

Kalpana Bhargava

Affiliations and Expertise

Defence Institute of Physiological and Allied Sciences (DIPAS), Defence Research and Development Organization (DRDO), Ministry of Defence, Government of India,Delhi, India

Robson Benjamin

Affiliations and Expertise

Department of Physics, American College, Tamilnadu, India

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