Biomolecular Interactions Part B

Biomolecular Interactions Part B

1st Edition - May 2, 2022
  • Editor: Arun Shukla
  • Hardcover ISBN: 9780128233535

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Description

Biomolecular Interactions: Part A, Volume 169, the latest release in the Methods in Cell Biology series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of timely topics, including Emerging Mechanisms of Targeted Protein Degradation by Molecular Glues, Design and use of programmable DNA Hydrogels,  Oligomerization of membrane receptors: Approaches to measure in live cells, Interactions of alpha-synuclein with biomolecules, Gel-electrophoresis based method for biomolecular interaction, Recombinant centrosome expression in bacterial system, Reconstituting CCL5-CCR5 complex for structural and mechanistic analysis, Protein engineering and design in ion channel receptors, and much more.

Key Features

  • Provides the authority and expertise of leading contributors from an international board of authors
  • Presents the latest release in the Methods in Cell Biology series
  • Updated release includes the latest information on biomolecular interactions instead of protein-protein interactions

Readership

Academic, government and industrial sectors

Table of Contents

  • 1. Emerging Mechanisms of Targeted Protein Degradation by Molecular Glues
    2. Design and use of programmable DNA Hydrogels
    3. Oligomerization of membrane receptors: Approaches to measure in live cells
    4. Interactions of alpha-synuclein with biomolecules
    5. Gel-electrophoresis based method for biomolecular interaction
    6. Recombinant centrosome expression in bacterial system
    7. Reconstituting CCL5-CCR5 complex for structural and mechanistic analysis
    8. Protein engineering and design in ion channel receptors
    9. The crosstalk of G-proteinsand phospholipases in cellular signaling
    10. Discovery of virus-host interactions using bioinformatics
    11. Measuring Ligand-receptor interactions at opioid receptors
    12. Label-free cell-based assays to unravel the biomolecular interactions involved in G-protein coupled receptor signaling
    13. Measuring ligand-receptorinteractionsusing Atomic Force Microscopy
    14. Reconstituting NTS1R signaling complex in lipid nanodisc
    15. Proximity labeling methods to study biomolecular interactions
    16. Super-resolution Microscopy approaches for monitoring protein trafficking and interaction
    17. Interaction of cytosolic proteins with synthetic antibody fragments using NanoBiT assays
    18. Reversible cross-linking to detect protein-protein interaction
    19. Assays to monitor the activity of atypical chemokine receptors

Product details

  • No. of pages: 362
  • Language: English
  • Copyright: © Academic Press 2022
  • Published: May 2, 2022
  • Imprint: Academic Press
  • Hardcover ISBN: 9780128233535

About the Serial Volume Editor

Arun Shukla

Arun Shukla
Dr. Arun K. Shukla obtained his M.Sc. (Master in Science) from the Center for Biotechnology at the Jawaharlal Nehru University in New Delhi, India. Dr. Shukla did his Ph.D. from the Department of Molecular Membrane Biology at the Max Planck Institute of Biophysics in Frankfurt, Germany. His Ph.D. research work was focused on structural studies of G Protein-Coupled Receptors (GPCRs).

Dr. Shukla subsequently carried out his post-doctoral work in the Department of Medicine at the Duke University in North Carolina, USA. During his post-doctoral research work, Dr. Shukla focused on understanding the biophysical and structural basis of ß-arrestin mediated regulation of GPCRs and non-canonical GPCR signaling. Dr. Shukla has served as an Assistant Professor in the Department of Medicine at the Duke University in Durham, North Carolina, USA.

Dr. Shukla is currently an Assistant Professor in Department of Biological Sciences and Bioengineering at the Indian Institute of Technology, Kanpur, India. Dr. Shukla is also an Intermediate Fellow of the Wellcome Trust-DBT India Alliance. The research program in Dr. Shukla’s laboratory is focused on understanding the molecular mechanism of activation, signaling and regulation of G Protein-Coupled Receptors.

Affiliations and Expertise

Assistant Professor, Indian Institute of Technology, Kanpur, India