Biomineralization and Biomaterials - 1st Edition - ISBN: 9781782423386, 9781782423560

Biomineralization and Biomaterials

1st Edition

Fundamentals and Applications

Authors: Conrado Aparicio Maria Pau Ginebra
eBook ISBN: 9781782423560
Hardcover ISBN: 9781782423386
Imprint: Woodhead Publishing
Published Date: 25th September 2015
Page Count: 482
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Description

Biomineralization is a natural process by which living organisms form minerals in association with organic biostructures to form hybrid biological materials such as bone, enamel, dentine and nacre among others. Scientists have researched the fundamentals of these processes and the unique structures and properties of the resulting mineralized tissues. Inspired by them, new biomaterials for tissue engineering and regenerative medicine have been developed in recent years.

Biomineralization and biomaterials: fundamentals and applications looks at the characteristics of these essential processes and natural materials and describes strategies and technologies to biomimetically design and produce biomaterials with improved biological performance.

Key Features

  • Provides a thorough overview of the biomineralization process
  • Presents the most recent information on the natural process by which crystals in tissues form into inorganic structures such as bone, teeth, and other natural mineralized tissues
  • Investigates methods for improving mineralization
  • Explores new techniques that will help improve the biomimetic process

Readership

Researchers working in Biomaterials and Tissue Engineering; Industry product development professionals;academics and students in biomimetics

Table of Contents

  • Preface
  • Part One: Fundamentals
    • 1: Shaping it up: Design and engineering of biominerals and crystalline materials from the bottom up
      • Abstract
      • Acknowledgments
      • 1.1 Introduction
      • 1.2 Crystalline properties
      • 1.3 Characterization and construction methods of crystals
      • 1.4 Biological crystalline materials
      • 1.5 Directing the evolution of mineralization-related proteins
      • 1.6 Outlook and conclusions
    • 2: Morphology control and molecular templates in biomineralization
      • Abstract
      • 2.1 Introduction
      • 2.2 Structural diversity
      • 2.3 Pathways of crystal formation and growth
      • 2.4 Molecular templates and morphology control in Nature
      • 2.5 Summary: Scope of biomineralization—Applications and challenges
    • 3: Physical chemistry of biological apatites
      • Abstract
      • 3.1 Introduction
      • 3.2 Composition of bone
      • 3.3 Constitution of biological nanocrystals
      • 3.4 Properties of biological apatites and synthetic analogs
      • 3.5 Conclusions and perspectives
    • 4: Mineralization processes in hard tissue: Bone
      • Abstract
      • 4.1 Introduction
      • 4.2 Composition of bone
      • 4.3 Bone mineralization process
      • 4.4 Pathological mineralization
      • 4.5 Mineralization of synthetic biomaterials
      • 4.6 Conclusion
    • 5: Mineralization processes in hard tissues: Teeth
      • Abstract
      • 5.1 Introduction
      • 5.2 Tooth formation: Odontogenesis
      • 5.3 Enamel mineralization
      • 5.4 Dentin mineralization
    • 6: Biomimetic mineralization of collagen
      • Abstract
      • 6.1 Prolog
      • 6.2 In vitro model systems for studying mechanisms of mineralization
      • 6.3 Ex situ studies of biological mineralization of collagenous tissue
      • 6.4 How does collagen control crystal nucleation and orientation?
      • 6.5 Influence of various parameters on collagen mineralization
      • 6.6 Concluding remarks
  • Part Two: Applications
    • 7: Ion substitution in biological and synthetic apatites
      • Abstract
      • 7.1 Introduction
      • 7.2 Ionic substitutions
      • 7.3 Hydroxyapatite
      • 7.4 Biological apatites
      • 7.5 Synthetic apatites
      • 7.6 Concluding remarks
    • 8: Accelerating mineralization of biomimetic surfaces
      • Abstract
      • 8.1 Introduction
      • 8.2 Metals
      • 8.3 Biomolecules and polymers
      • 8.4 Ceramics
    • 9: Biomimetic mineralization of hydrogels
      • Abstract
      • Acknowledgments
      • 9.1 Introduction
      • 9.2 Overview of biomimetic strategies to promote hydrogel mineralization
      • 9.3 Biomimetic mineralization with CaP
      • 9.4 Biomimetic mineralization with CaCO3
      • 9.5 Biomimetic mineralization with silica
      • 9.6 Conclusion
    • 10: Biomimetic mineralization of ceramics and glasses
      • Abstract
      • 10.1 Introduction: The biomimetic approach
      • 10.2 CaP coatings: Bioactivating nonbioactive materials
      • 10.3 Bioactive ceramics
      • 10.4 The biomineralization process in CaPs and bioactive glasses
      • 10.5 Conclusions
    • 11: Biomineralization of metals using chemical and heat treatments
      • Abstract
      • 11.1 Introduction
      • 11.2 Background of biomineralization on metals
      • 11.3 Various approaches for biomineralization on metals
      • 11.4 Simple chemical and heat treatments for biomineralization on metals
      • 11.5 Clinical applications of metallic biomaterials inducing biomineralization
      • 11.6 Future aspects of biomineralization on metals
    • 12: Biomaterials for catalysed mineralization of dental hard tissues
      • Abstract
      • Acknowledgements
      • 12.1 Introduction
      • 12.2 Agents to facilitate remineralization through dental materials
      • 12.3 Applied dental restorative materials for catalysed bioremineralization
      • 12.4 Future trends and research in bioactive dental restorative materials
    • 13: Designing biomaterials based on biomineralization for bone repair and regeneration
      • Abstract
      • Acknowledgments
      • 13.1 Introduction
      • 13.2 Clinical need for bone replacement/regeneration
      • 13.3 Bone structure and function
      • 13.4 Bioactive ceramics for bone replacement/regeneration
      • 13.5 Assessment of in vitro bioactivity
      • 13.6 The influence of material properties in rendering self-mineralized polymers
      • 13.7 Engineering a bioactive 3D structure for bone TE
      • 13.8 Concluding remarks and future perspectives
    • 14: Bio-inspired calcium phosphate materials for hard-tissue repair
      • Abstract
      • 14.1 Introduction
      • 14.2 Biomimetics
      • 14.3 Balancing the requirements for successful in vivo integration
      • 14.4 Natural solutions
      • 14.5 Ceramic processing
      • 14.6 The future of biomimetic-inspired calcium phosphate materials
    • 15: Mineralization of fibers for bone regeneration
      • Abstract
      • 15.1 Introduction
      • 15.2 Fibers as scaffolds for bone regeneration
      • 15.3 Biomimetic mineralization of fibers
      • 15.4 Biological effects of mineralized fibers
      • 15.5 Conclusions
  • Index

Details

No. of pages:
482
Language:
English
Copyright:
© Woodhead Publishing 2016
Published:
Imprint:
Woodhead Publishing
eBook ISBN:
9781782423560
Hardcover ISBN:
9781782423386

About the Author

Conrado Aparicio

Affiliations and Expertise

Associate Professor, University of Minnesota, USA

Maria Pau Ginebra

Affiliations and Expertise

Professor, Universitat Politècnica de Catalunya, Spain