Biomaterials Science - 4th Edition - ISBN: 9780128161371

Biomaterials Science

4th Edition

An Introduction to Materials in Medicine

Editors: William Wagner Shelly Sakiyama-Elbert Guigen Zhang Michael Yaszemski
Hardcover ISBN: 9780128161371
Imprint: Academic Press
Published Date: 4th March 2020
Page Count: 1500
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Biomaterials Science: An Introduction to Materials in Medicine, Fourth Edition, is the most comprehensive text on biomaterials science, from principles to applications. It provides a balanced, insightful approach to both the learning of the science and technology of biomaterials, acting as a key reference for practitioners involved in the applications of materials in medicine. In this new edition, there are key updates to reflect the latest relevant research in the field, particularly in applications in nanotechnology, robotic implantation, and biomaterials utilized in cancer research detection and therapy. Other additions include regenerative engineering, 3D printing, personalized medicine and organs on a chip.

Based on customer feedback, the new edition also features a consolidation of redundant material to ensure clarity and focus. Where appropriate, end-of-chapter exercises have been included with online solutions available.

Key Features

  • Provides the most comprehensive coverage of principles and applications of all classes of biomaterials
  • Edited and contributed by the best-known figures in the biomaterials field today; fully endorsed and supported by the Society for Biomaterials
  • Fully revised and updated to address issues of translation, nanotechnology, additive manufacturing, organs on chip, precision medicine, and much more
  • Includes learning exercises at the end of each chapter


Materials science and engineering and Biomedical Engineering undergraduate & graduate students and post-docs; Academic and professional researchers in R&D and clinical practice. Also applicable to life and biological sciences and mechanical engineering

Table of Contents

Part 1: Materials Science and Engineering
1. Properties of Materials
2. Classes of Materials Used in Medicine

Part 2: Biology and Medicine
3. Some Background Concepts
4. Host Reaction to Biomaterials and Their Evaluation
5. Biological Testing of Biomaterials
6. Degradation of Materials in the Biological Environment
7. Applications of Biomaterials
8. Applications of Biomaterials in Functional Tissue Engineering

Part 3: Practical Aspects of Biomaterials
9. Implants, Devices, and Biomaterials: Special Considerations
10. Translation


No. of pages:
© Academic Press 2020
4th March 2020
Academic Press
Hardcover ISBN:

About the Editor

William Wagner

William Wagner, PhD Director of the McGowan Institute for Regenerative Medicine & Professor of Surgery, Bioengineering and Chemical Engineering, University of Pittsburgh William R. Wagner is the Director of the McGowan Institute for Regenerative Medicine as well as a Professor of Surgery, Bioengineering and Chemical Engineering at the University of Pittsburgh. He also currently serves as Chairman of the Tissue Engineering and Regenerative Medicine International Society (TERMIS) – Americas, the Deputy Director of the NSF Engineering Research Center on “Revolutionizing Metallic Biomaterials” and Chief Scientific Officer of the Armed Forces Institute of Regenerative Medicine. Professor Wagner is the Founding Editor and Editor-in-Chief of one of the leading biomaterials and biomedical engineering journals, Acta Biomaterialia, and currently serves on the editorial boards of the Journal of Biomedical Materials Research Part A, Biotechnology and Bioengineering, Organogenesis, Experimental Biology & Medicine, and the Journal of Tissue Engineering and Regenerative Medicine. Dr. Wagner is a past president of the American Society for Artificial Internal Organs (ASAIO; 2010-2011) and has served on the Executive Board of the International Federation of Artificial Organs (IFAO). He is a fellow and former vice president of the American Institute for Medical and Biological Engineering (AIMBE; 2000) and has been elected a fellow of the Biomedical Engineering Society (2007), the International Union of Societies for Biomaterials Science and Engineering (2008), the American Heart Association (2001) and TERMIS (2015). He has served as Chairman for the Gordon Research Conference on Biomaterials: Biocompatibility & Tissue Engineering as well as for the Biomedical Engineering Society Annual Meeting, ASAIO, and the First World Congress of TERMIS. He was previously recognized by selection to the “Scientific American 50”, the magazine’s annual list recognizing leaders in science and technology from the research, business and policy fields. In 2011 he was awarded the Society for Biomaterials Clemson Award for Applied Research, in 2012 he received the Chancellor’s Distinguished Research Award from the University of Pittsburgh and in 2013 he received the TERMIS Senior Scientist Award. Dr. Wagner's research interests are generally in the area of cardiovascular engineering with projects that address medical device biocompatibility and design, hypothesis-driven biomaterials development, tissue engineering, and targeted imaging.

Affiliations and Expertise

Director of the McGowan Institute for Regenerative Medicine and Professor of Surgery, Bioengineering and Chemical Engineering, University of Pittsburgh, USA

Shelly Sakiyama-Elbert

Shelly Sakiyama-Elbert, PhD Professor of Biomedical Engineering & Associate Chair for Graduate Studies Washington University Shelly Sakiyama-Elbert joined the faculty in Biomedical Engineering at Washington University in 2000, where she is currently a professor of Biomedical Engineering and the Associate Chair for Graduate Studies. Her research focuses on developing biomaterials for drug delivery and cell transplantation for the treatment of peripheral nerve and spinal cord injury. She has written 5 book chapters and over 60 articles in peer-reviewed journals. She has 8 U.S. patents and 2 patent applications submitted. Her research is funded by the National Institute of Neurological Disorders and Stroke and the National Institute of Health. Previously, she received early career awards from the Whitaker Foundation and the WH Coulter Foundation. She is currently on the Tissue Engineering and Regenerative Medicine International Society (TERMIS): Americas Council and served on the Biomedical Engineering Society (BMES) Board of Directors from 2009-2012. She joined the College of Fellows for the American Institute for Medical and Biological Engineering in 2011 and was elected a fellow of the Biomedical Engineering Society in 2013. Her other professional service includes serving as an associate editor for Biotechnology and Bioengineering, a member of the Editorial Board of Acta Biomaterialia, member of the Long Range Planning Committee for the Society for Biomaterials (SFB) (2003-05), and serving as a standing member of the Biomaterials/ Biointerfaces (BMBI) study section for the NIH (2010- 2013). She served as chair for the 2013 Gordon Research Conference on Biomaterials & Tissue Engineering. She is currently the co-president of the Association of Women Faculty and served as a provost faculty fellow from 2012-2013.

Affiliations and Expertise

Professor of Biomedical Engineering and Associate Chair for Graduate Studies, Washington University, USA

Guigen Zhang

Guigen Zhang, PhD Professor, Clemson University Dr. Zhang began his academic career at Tongji University (Shanghai, China) in 1987. After his doctoral and postdoctoral trainings, he resumed his research career at Northwestern University in Illinois. Before joining Clemson University in fall of 2008, Dr. Zhang was an Associate Professor at the University of Georgia where he pioneered a bio-micro/nanotechnology program. Dr. Zhang has served as major professor to six doctoral students and two master students. All of his doctoral graduates are pursuing research careers in academia (e.g., Stanford, UIUC) and in industries (e.g., IBM, COMSOL). He also served on graduate advisory committees for another three doctoral students and two master students. He has mentored three postdoctoral fellows and numerous undergraduate students. He serves on the editorial board of the Journal of Biological Engineering and is an education editor for the Biomaterials Forum. Dr. Zhang has served as PI on several NIH and NSF grants and participated in the NIH study sessions and NSF review panels numerous times in the areas of biotechnology and nanotechnology covering topics such as chip based sensors, sensors and detectors for environmental monitoring, nanoscale drug delivery, and MEMS and NEMS devices.

Affiliations and Expertise

Professor, Clemson University, USA

Michael Yaszemski

Michael Yaszemski, PhD, MD Professor of Orthopaedics and Bioengineering & Director of the Tissue Engineering and Biomaterials Laboratory, Mayo Clinic Dr. Yaszemski is a Professor of Orthopaedics and Bioengineering at the Mayo Clinic, and the Director of the Tissue Engineering and Biomaterials Laboratory. His clinical practice encompasses spinal surgery and sacropelvic tumor surgery. His research interests are in the synthesis and characterization of novel degradable polymers for use in bone regeneration, spinal cord regeneration via tissue engineering strategies, and controlled local drug delivery to musculoskeletal tumors.

Affiliations and Expertise

Professor of Orthopedics and Bioengineering and Director of the Tissue Engineering and Biomaterials Laboratory, Mayo Clinic, USA

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