Biomaterials and Medical Device - Associated Infections

1st Edition

Editors: L Barnes Ian Cooper
Hardcover ISBN: 9780857095978
eBook ISBN: 9780857097224
Imprint: Woodhead Publishing
Published Date: 4th November 2014
Page Count: 278
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Table of Contents

    <li>List of contributors</li> <li>Woodhead Publishing Series in Biomaterials</li> <li>Part One: Introduction to biomaterials and medical device-related infections<ul><li>1: Introduction to biomaterials and medical device-associated infections<ul><li>Abstract</li><li>1.1 History of biomaterials</li><li>1.2 Overview of current medical devices and applications</li><li>1.3 Overview of problems associated with medical devices</li><li>1.4 Introduction to the structure of this book</li><li>References</li></ul></li><li>2: Biofilms and implant-associated infections<ul><li>Abstract</li><li>2.1 Introduction</li><li>2.2 Microbial profile of implant-associated infections</li><li>2.3 Relevance of biofilms in implant-associated infections</li><li>2.4 Structure and composition of biofilms</li><li>2.5 Pathogenesis of biofilm infection</li><li>2.6 Future trends</li><li>2.7 Further information and advice</li><li>References</li></ul></li><li>3: <i>In vivo</i> infection studies<ul><li>Abstract</li><li>3.1 Introduction</li><li>3.2 Legitimacy of animal studies</li><li>3.3 Choosing the right animal model to study device-associated infections</li><li>3.4 Pros and cons of <i>in vivo</i> infection studies</li><li>3.5 Correlation of outcome between animal and clinical studies</li><li>3.6 Conclusion and future trends</li><li>3.7 Sources of further information and advice</li><li>Acknowledgments</li><li>References</li></ul></li><li>4: Diagnosis of biofilm-associated infections in medical devices<ul><li>Abstract</li><li>4.1 Introduction</li><li>4.2 Importance of detection of biofilm</li><li>4.3 Sites of biofilm formation</li><li>4.4 Collection of samples for biofilm detection</li><li>4.5 Examples of methods for the detection of biofilms associated with infections</li><li>4.6 Future trends</li><li>4.7 Conclusion</li><li>Acknowledgement</li><li>References</li></ul></li><li>5: Diagnosis and treatment of implant-associated infections<ul><li>Abstract</li><li>5.1 Introdu


Despite advances in materials and sterilisation, patients who receive biomaterials of medical device implants are still at risk of developing an infection around the implantation site. This book reviews the fundamentals of biomaterials and medical device related infections and methods and materials for the treatment and prevention of infection. The first part of the book provides readers with an introduction to the topic including analyses of biofilms, diagnosis and treatment of infection, pathology and topography. The second part of the book discusses a range of established and novel technologies and materials which have been designed to prevent infection.

Key Features

  • Provides analysis of biofilms and their relevance to implant associated infections.
  • Assesses technologies for controlling biofilms.
  • Considers advantages and disadvantages of in vivo infection studies.


Materials scientists and engineers concerned with producing infection resistant/antimicrobial materials, microbiologists and orthopaedic clinicians.


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© Woodhead Publishing 2015
Woodhead Publishing
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About the Editors

L Barnes Editor

Dr Barnes is a Senior Lecturer at the University of Brighton

Affiliations and Expertise

Senior Lecturer, Pharmacy and Biomolecular Sciences, University of Brighton, Brighton, UK

Ian Cooper Editor

Affiliations and Expertise

Senior Lecturer, Pharmacy and Biomolecular Sciences, University of Brighton, Brighton, UK