Biologics and Biology-based Regenerative Treatment Approaches in Periodontics, An Issue of Dental Clinics of North America

1st Edition, Volume 66-1 - November 22, 2021
Editors: Alpdogan Kantarci, Andreas Stavropoulos, Anton Sculean
Language: English
Hardback ISBN:
9 7 8 - 0 - 3 2 3 - 8 3 5 3 0 - 5
eBook ISBN:
9 7 8 - 0 - 3 2 3 - 8 3 5 3 1 - 2

In this issue of Dental Clinics, guest editors Alpdogan Kantarci, Andreas Stavropoulos, and Anton Sculean bring their considerable expertise to the topic of Biologics and Biology-… Read more

Biologics and Biology-based Regenerative Treatment Approaches in Periodontics, An Issue of Dental Clinics of North America

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In this issue of Dental Clinics, guest editors Alpdogan Kantarci, Andreas Stavropoulos, and Anton Sculean bring their considerable expertise to the topic of Biologics and Biology-based Regenerative Treatment Approaches in Periodontics.

Cover image
Title page
Table of Contents
Copyright
Contributors
Forthcoming Issues
Introduction: Vision of Regenerative Periodontology
Biological Basis of Periodontal Regeneration
Key points
Introduction
Repair or regeneration: conceptual to biological wound healing
Cellular regulation of periodontal regeneration
Molecular basis of wound healing and periodontal regeneration
Summary
Clinics care points
Disclosure
Decontamination and Biomodification of Periodontally Affected Root Surface for Successful Regeneration: Is There Room for Improvement?
Key points
Introduction
Root surface modifier strategies to treat periodontally affected teeth
Root surface modifier strategies to improve clinical outcomes of periodontal surgeries
Root surface modifier strategies to enhance root coverage procedures
Future perspectives
Summary
Clinics care points
Inflammation and Periodontal Regeneration
Key points
Introduction
Treatment of periodontal diseases: the unchanged story of a progressive inflammatory disease
Host modulatory therapies directed at the regeneration of the periodontium
Host modulation therapies directed at resolution of inflammation in regenerative periodontal treatment
New avenues in the regeneration of periodontal tissues
Clinics care points
Disclosure
Stem Cell Applications in Periodontal Regeneration
Key points
Introduction
A cellular approach to periodontal regeneration
What are stem cells?
Defining properties of mesenchymal stem cells
Cells with potential for use in periodontal regeneration
Stem cells of dental origin for periodontal regeneration
Stem cells from human exfoliated deciduous teeth
Extraoral stem cells for periodontal regeneration
Cell sheets for periodontal regeneration
Human clinical trials for cell-based periodontal regeneration
Future cell-based therapies for periodontal regeneration
Limitations of stem cell therapy for periodontal regeneration
Summary
Clinics care points
The Evolution of Surgical Techniques and Biomaterials for Periodontal Regeneration
Key points
Introduction
The early stages
Papilla preservation flaps
Minimally invasive flaps
Combined intrabony- and soft tissue- regenerative approaches
Biomaterials
Concluding remarks
Clinics care points
Soft Tissue Regeneration at Natural Teeth
Key points
Introduction
Biologic background
Surgical therapy for single recessions
Surgical therapy for multiple adjacent gingival recessions
Soft tissue biomaterials and substitutes
Summary
Clinics care points
Regenerative Periodontal Therapy in Intrabony Defects and Long-Term Tooth Prognosis
Key points
Why periodontal regenerative procedures?
Longevity of treatment
Long-term outcomes in intrabony defects
Long-term tooth survival
Summary
Clinics care points
Scaffolds in Periodontal Regenerative Treatment
Key points
Introduction
Scaffold designing and fabrication concept for periodontal regeneration
Monophasic scaffold approaches for periodontal regeneration
Multiphasic scaffold approach for targeting tissue-specific regeneration
Custom-designed 3-dimensional scaffold for a personalized periodontal approach
Conclusion and future implications
Clinics care points
Disclosure
Nanomedicine and Periodontal Regenerative Treatment
Key points
Introduction
Chitosan-based nanomaterials
Polylactic-co-glycolic acid
Carbon quantum dots
Mesoporous silica
Clinical perspectives
Clinics care points
Disclosure
Biomarkers and Periodontal Regenerative Approaches
Key points
Introduction
Biological markers: biomarkers
Biomarker research in periodontology
Biomarkers of periodontal regeneration: obstacles
Biomarkers of periodontal regeneration: potential targets
Biomarkers of periodontal regeneration: evidence
Discussion
Clinics care points
Disclosure